Results 1 to 10 of about 6,539,286 (354)

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]

open access: yes, 1996
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Feng, G.J.   +4 more
core   +3 more sources

Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]

open access: yes, 2011
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne   +3 more
core   +1 more source

Delayed Tibial-platform Periprosthetic Stress Fracture after Unicompartmental Knee Arthroplasty: Uncommon and Devastating Complication

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation, 2018
Periprosthetic fracture around total knee arthroplasty (TKA) is a well-described complication. Yet, report of medial tibial plateau stress fracture after unicompartmental knee arthroplasty (UKA) is limited.
Hung Yuk-Wah   +4 more
doaj   +1 more source

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

open access: yesJournal of Neuroscience, 2006
Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of β-amyloid 42 (Aβ42) and cause familial Alzheimer's disease (FAD).
Holly Oakley   +11 more
semanticscholar   +1 more source

Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

open access: yes, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola   +3 more
core   +1 more source

The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. [PDF]

open access: yes, 2013
BackgroundThe current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.FindingsA/Anhui/1/2013 (H7N9) virus was administered by intranasal instillation to groups of mice and ...
Bao, Linlin   +19 more
core   +3 more sources

Highly Effective Ex Vivo Gene Manipulation to Study Kidney Development Using Self-Complementary Adenoassociated Viruses

open access: yesThe Scientific World Journal, 2014
Background. Ex vivo culture of intact embryonic kidney has become a powerful system for studying renal development. However, few methods have been available for gene manipulation and have impeded the identification and investigation of genes in this ...
Tie-Lin Chen   +7 more
doaj   +1 more source

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. [PDF]

open access: yes, 2019
There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these
Atkinson, Mark A   +6 more
core   +2 more sources

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.

open access: yesCell, 1996
Huntington's disease (HD) is one of an increasing number of neurodegenerative disorders caused by a CAG/polyglutamine repeat expansion. Mice have been generated that are transgenic for the 5' end of the human HD gene carrying (CAG)115-(CAG)150 repeat ...
L. Mangiarini   +10 more
semanticscholar   +1 more source

Kinetic Analysis of Poly(-caprolactone)/poly(lactic acid) Blends with Low-cost Natural Thermoplastic Starch

open access: yesActa Chimica Slovenica, 2020
Non-isothermal thermogravimetry in an inert atmosphere was used to investigate the thermal stability of poly(e-caprolactone) (PCL), polylactide (PLA), thermoplastic starch (TPS) and their binary (PCL/PLA,PCL/TPS andPLA/TPS) and ternary (PCL/PLA/TPS ...
Vesna Ocelić Bulatović   +2 more
doaj   +1 more source

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