Results 31 to 40 of about 115,102 (75)
Interpretation of immunofluorescence slides by deep learning techniques: anti-nuclear antibodies case study [PDF]
arXiv, 2023 Nowadays, diseases are increasing in numbers and severity by the hour. Immunity diseases, affecting 8\% of the world population in 2017 according to the World Health Organization (WHO), is a field in medicine worth attention due to the high rate of disease occurrence classified under this category.
arxiv
Journal of Immunology Research, 2020 Objectives. Both thymic stromal lymphopoietin (TSLP) and dendritic cells (DCs) are involved in many autoimmune diseases, but the potential roles of TSLP and DCs in bullous pemphigoid (BP) have not been clarified. We sought to explore the contributions of
Si-Zhe Li +4 more
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Frontiers in Immunology, 2023 BackgroundBullous pemphigoid (BP) is a common subepidermal bullous disorder that lacks adequate treatment alternatives. Dupilumab, an anti-interleukin (IL) 4 receptor α antibody blocking Th2 molecules IL-4 and 13, has been used off-label and shown to be ...
Si-Hang Wang +4 more
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Computational strategies for dissecting the high-dimensional complexity of adaptive immune repertoires [PDF]
, 2017 The adaptive immune system recognizes antigens via an immense array of antigen-binding antibodies and T-cell receptors, the immune repertoire. The interrogation of immune repertoires is of high relevance for understanding the adaptive immune response in disease and infection (e.g., autoimmunity, cancer, HIV).
arxiv +1 more source
Acceleration of Precision Medicine in Pediatric Rheumatic and Immunologic Diseases
Xiehe Yixue Zazhi, 2023 Rheumatic and immunologic diseases in children may involve multiple genes and interactions between genetic and environmental factors. There are no validated biomarkers that are predictive of treatment response.
MA Mingsheng, SONG Hongmei
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Clustering and Retrieval Method of Immunological Memory Cell in Clonal Selection Algorithm [PDF]
, 2018 The clonal selection principle explains the basic features of an adaptive immune response to a antigenic stimulus. It established the idea that only those cells that recognize the antigens are selected to proliferate and differentiate. This paper explains a computational implementation of the clonal selection principle that explicitly takes into ...
arxiv +1 more source
Regulation of splenic monocyte homeostasis and function by gut microbial products
iScience, 2021 Summary: Splenic Ly6Chigh monocytes are innate immune cells involved in the regulation of central nervous system-related diseases. Recent studies have reported the shaping of peripheral immune responses by the gut microbiome via mostly unexplored ...
Panayota Kolypetri +9 more
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Journal of Ginseng Research, 2016 Background: It is not clear whether ginseng affects cyclosporine A (CsA)-induced desirable immunosuppressive action. In this study, we evaluated the immunological influence of combined treatment of ginseng with CsA. Methods: Using CD4+ T cells from mouse
Seong Beom Heo +5 more
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Marchuk's models of infection diseases: new developments [PDF]
arXiv, 2020 We consider mathematical models of infection diseases built by G.I. Marchuk in his well known book on immunology. These models are in the form of systems of ordinary delay differential equations. We add a distributed control in one of the equations describing the dynamics of the antibody concentration rate.
arxiv
Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation
Cell Reports, 2020 Summary: Tim-1, a phosphatidylserine receptor expressed on B cells, induces interleukin 10 (IL-10) production by sensing apoptotic cells. Here we show that mice with B cell-specific Tim-1 deletion develop tissue inflammation in multiple organs including ...
Sheng Xiao +15 more
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