Progressive multifocal leukoencephalopathy successfully treated with mefloquine and literature review [PDF]
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection due to reactivation of John Cunningham virus (JCV). The diagnosis depends on evidence from clinical, imaging, and virologic studies.
Sungjoon Yoon+3 more
doaj +1 more source
Case report of a patient with progressive multifocal leukoencephalopathy under treatment with dimethyl fumarate [PDF]
BACKGROUND: Progressive multifocal leukoencephalopathy is a severe demyelinating disease caused by the polyoma JC virus in patients with reduced immunocompetence.
Antje Bornemann+4 more
core +1 more source
The effect of sample size on field dependence of Jc for MgB2 superconductor [PDF]
A strong effect of sample size on magnetic Jc(H) was observed for bulk MgB2 when Jc is obtained directly from the critical state model. Thus obtained zero-field Jc (Jc0) decreases strongly with the sample size, attaining a constant value for the samples larger than a few millimetres.
arxiv +1 more source
Polymerase chain reaction for the laboratory diagnosis of aseptic meningitis and encephalitis [PDF]
A protocol for testing cerebrospinal fluid specimens using a range of PCR assays for the diagnosis of central nervous system infection was developed and used to test prospectively 383 specimens.
MARISA CHESKY+4 more
doaj +1 more source
HIV-associated progressive multifocal leukoencephalopathy. Current perspectives [PDF]
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, caused by the polyomavirus JC and occurring almost exclusively in the context of severe immune depression.
Ciardi, M. R.+6 more
core +1 more source
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by polyomavirus John Cunningham (JC) virus.
Tanmay S Panchabhai+4 more
doaj +1 more source
AIDS-related progressive multifocal leukoencephalopathy
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão+5 more
doaj +1 more source
JC Virus Infection of Lymphocytes—Revisited [PDF]
JC virus (JCV), the causative agent of the fatal human demyelinating disease progressive multifocal leukoencephalopathy (PML), is an opportunistic papovavirus that infects and destroys oligodendrocytes, the myelin-producing cells of the central nervous system.
Eugene O. Major+3 more
openaire +3 more sources
Immunological biomarkers identifying natalizumab-treated multiple sclerosis patients at risk of progressive multifocal leukoencephalopathy [PDF]
Natalizumab-induced progressive multifocal leukoencephalopathy (PML) appears to be unleashed by complex interactions between viral and immunological host factors leading the latent form of JC virus to become pathogenic.
A.SOTTINI+8 more
core +1 more source
Copy Number Heterogeneity of JC Virus Standards [PDF]
ABSTRACT Quantitative PCR is a diagnostic mainstay of clinical virology, and accurate quantitation of viral load among labs requires the use of international standards. However, the use of multiple passages of viral isolates to obtain sufficient material for international standards may result in genomic changes that complicate their use as ...
Keith R. Jerome+6 more
openaire +3 more sources