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Progressive multifocal leukoencephalopathy [PDF]

Romanian Journal of Neurology, 2008
Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus.
Rosca Elena Cecilia, Mihaela Simu, Ruxandra Dana Chirileanu, M. Bednar, Ovidiu Rosca   +4 more
doaj   +3 more sources

Natalizumab-associated progressive multifocal leukoencephalopathy [PDF]

Frontiers in Neurology
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain resulting from infection of oligodendrocytes by JC virus (JCV) typically occurring in association with defects of cell-mediated immunity.
Trevor Glenn, Joseph R. Berger, Caleb R. S. McEntire   +2 more
doaj   +2 more sources

A case of progressive multifocal leukoencephalopathy in an adult patient with ADA-SCIDPML in ADA-SCID [PDF]

Journal of Human Immunity
This case report describes progressive multifocal leukoencephalopathy in a patient with ADA-SCID status after gene therapy. Persistent metabolic dysfunction likely contributed to JC virus reactivation, highlighting this rare complication of ADA-SCID and ...
Hannah Shin, Lori Broderick, Jessica Azevedo, Caitlin Mulligan, Kari Hird, Vanessa Goodwill, Courtney Parkin, Stephanie Mortensen, Madisen Traveller, Ahmad Rayes, John Bohnsack, Donald B. Kohn, Teresa K. Tarrant, Michael Hershfield, Jonathan J. Lyons   +14 more
doaj   +2 more sources

Progressive multifocal leukoencephalopathy in rheumatoid arthritis and biological therapies: a case report and review of the literature [PDF]

Journal of Medical Case Reports
Background Progressive multifocal leukoencephalopathy is a rare but potentially fatal disease caused by infection of the central nervous system with John Cunningham polyomavirus.
Barbara Bergmans, Gerwin Roks, Eugène van Puijenbroek, Esther de Vries, Jean-Luc Murk   +4 more
doaj   +2 more sources

A rare case of progressive multifocal leukoencephalopathy [PDF]

Radiology Case Reports
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system (CNS) due to John Cunningham (JC) virus reactivation most often in immunocompromised patients.
Jayanthraj Gone, DO, Tyler Fontaine, DO, Gaurav Kumar, MD   +2 more
doaj   +2 more sources

Progressive multifocal leukoencephalopathy in a patient with novel mutation in the RAC2 gene: a case report

Journal of Medical Case Reports, 2022
Background Progressive multifocal leukoencephalopathy is a rare demyelinating disease that is often secondary to lytic destruction of oligodendrocytes and, to a lesser extent, to astrocytes’ response to human neurotrophic John Cunningham polyomavirus ...
Sima Bahrami, Saba Arshi, Mohammad Nabavi, Mohammad Hassan Bemanian, Morteza Fallahpour, Afshin Rezaeifar, Sima Shokri   +6 more
doaj   +1 more source

A case of progressive multifocal leukoencephalopathy in a post-kidney transplant patient with improvement after discontinuation of immunosuppressive drugs and combination therapy with mefloquine and mirtazapine

Renal Replacement Therapy, 2023
Background Progressive multifocal leukoencephalopathy is a rare disease, but the prognosis is very poor, especially in the immunosuppressed state with a non-HIV background, and there is no established treatment.
Neri Sone, Hiroki Nishiwaki, Mayu Shimokawa, Keishu Kawanishi, Tsuyoshi Oshiro, Reiji Takami, Natsuki Taira, Masahito Amagasa, Shinya Omiya, Tadahide Maezumi, Yoko Nabeshima, Kazuo Nakamichi, Yoshiharu Miura, Fumihiko Koiwa   +13 more
doaj   +1 more source

AIDS-related progressive multifocal leukoencephalopathy

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão, Lissa Rodrigues Machado da Silva, Luiz Carlos Silva Souza, Nathalia de Mello Bisso, Marília Dalva Turchi, Adriana Oliveira Guilarde   +5 more
doaj   +1 more source

Clinical and Radiological Characterization of Progressive Multifocal Leukoencephalopathy in HIV-Infected Patients: A Retrospective Analysis and Review of the Literature

Acta Médica Portuguesa, 2015
Introduction: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection ...
Luís Augusto, Nélia Neves, Carina Reis, Cândida Abreu, António Sarmento   +4 more
doaj   +1 more source

Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy

Emerging Infectious Diseases, 2022
Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment.
Nicolas Lambert, Solène Dauby, Dominique Dive, Bernard Sadzot, Pierre Maquet   +4 more
doaj   +1 more source