Results 31 to 40 of about 17,221 (177)

A decade of natalizumab and PML: Has there been a tacit transfer of risk acceptance? [PDF]

, 2016
The interplay between each of the stakeholder's responsibilities and desires clearly has resulted in continued widespread use of natalizumab with substantial risks and an ongoing quest for better risk mitigation.
Clifford, DB, Major, EO, Yousry, TA
core   +1 more source

High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]

, 2011
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG, Cao, Q, Green, KG, Jacobson, PA, Long-Boyle, JR, McGlave, PB, Miller, JS, Rogosheske, J, Wagner, JE, Weisdorf, DJ   +9 more
core   +1 more source

Adverse reactions of biological therapies in patients with psoriasis [PDF]

, 2017
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R., Limbău, Alexandra M., Mitran, Cristina I., Mitran, Mădălina I., Sârbu, Maria I., Tampa, Mircea   +5 more
core   +4 more sources

Brainstem progressive multifocal leukoencephalopathy

European Journal of Neurology, 2020
AbstractBackground and purposeProgressive multifocal leukoencephalopathy (PML) is a severe infection caused by the polyomavirus JC that develops in the central nervous system (CNS) of immunosuppressed patients. The infection frequently starts in the brain hemispheres and can spread into other CNS regions such as the brainstem.
Gautier Breville, Igor J. Koralnik, Patrice H. Lalive   +2 more
openaire   +3 more sources

The Effect of Ocrelizumab on Anti‐JC Virus Antibody Index

Brain and Behavior, Volume 16, Issue 5, May 2026.
Synopsis: This study of 553 MS patients found that anti‐JC virus (JCV) antibody indices remain stable during the first 2 years of ocrelizumab treatment. While peripheral B‐cells were significantly depleted and serum immunoglobulins (IgG, IgM, IgA) showed modest declines, the JCV antibody index did not change significantly.
Akash Virupakshaiah, Alexander J. Gill, Vinicius A. Schoeps, Emma Wilson, James Wilson, David Do, Amit Bar‐Or, Dina Jacobs, Joseph R. Berger   +8 more
wiley   +1 more source

JCV-specific T-cells producing IFN-gamma are differently associated with PmL occurrence in HIV patients and liver transplant recipients [PDF]

, 2015
Aim of this work was to investigate a possible correlation between the frequency of JCV-specific T-cells and PML occurrence in HIV-infected subjects and in liver transplant recipients.
Agrati, C, Angrisani, M, Baldini, F, Berno, G, Bolognese, A., Bordoni, V, Capobianchi, Mr, Cimini, E, Colasanti, M, Di Cello, P, Ettorre, Gm, Giancola, Ml, Izzo, Luciano, Izzo, Paolo, Pugliese, Federico   +14 more
core  

Severe leukoencephalopathy with fulminant cerebral edema reflecting immune reconstitution inflammatory syndrome during HIV infection: a case report [PDF]

, 2010
Introduction Immune reconstitution inflammatory syndrome is a well-known complication in HIV-infected patients after initiation of highly active antiretroviral therapy resulting in rapid CD4+ cell count recovery and suppression of viral load.
Christian Oelschlaeger, Rainer Dziewas, Doris Reichelt, Jens Minnerup, Thomas Niederstadt, Erich B Ringelstein, Ingo W Husstedt   +6 more
core   +2 more sources

Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient [PDF]

Case Reports in Neurology, 2013
<b><i>Background:</i></b> Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients. PML is rarely reported in cases with no underlying disease or immunosuppression-associated condition. <b><i>Case Report:</i></b>
Krisztina K. Johansen, Sverre H. Torp, Jana Rydland, Jan O. Aasly   +3 more
openaire   +3 more sources

Reversible cerebral vasoconstriction syndrome: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1162-1180, May 2026.
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa, Abner da Silva Machado, Arthur de Oliveira Veras, Thiago Oscar Goulart, Sarah Galassi Tatsuta, Trajano Aguiar Pires Gonçalves, Eva Rocha, Octávio Marques Pontes‐Neto   +7 more
wiley   +1 more source

Dynamics of complete responses (CRs) in patients with relapsed or refractory follicular lymphoma (R/R FL) treated with odronextamab in the ELM‐2 study

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Complete response (CR) is an important treatment goal in follicular lymphoma (FL). In relapsed or refractory (R/R) FL, CR rates decline, and disease progression accelerates with each treatment line, with particularly poor outcomes in patients with high‐risk features.
Stefano Luminari, Ana Jiménez‐Ubieto, Geoffrey Chong, David Tucker, Srikanth Ambati, Chinjune Lin, Hesham Mohamed, Jurriaan Brouwer‐Visser, Chetachi Akunna Otele, Giovanni Antico, Jose C. Villasboas   +10 more
wiley   +1 more source