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Progressive multifocal leukoencephalopathy
doi:10.3969/j.issn.1672⁃6731.2020.03 ...
Xiao⁃ling YAN
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Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient [PDF]
Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients.
Krisztina K. Johansen +3 more
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Progressive multifocal leukoencephalopathy [PDF]
A 58-year-old woman admitted to the hospital had a 3-month history of progressive neurologic deterioration characterized by severe global aphasia and bilateral limb weakness, greater on the right. The patient had a 10-year history of systemic lupus erythematosus (SLE). Polyarthritis had been present for 6 weeks before the …
Henderson, R. D. +3 more
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Progressive multifocal leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy is a rare, opportunistic infection of the central nervous system caused by the John Cunningham virus (JCV). There is no effective antiviral treatment available, and restoring immunocompetence is essential for survival. If this occurs too quickly, however, the inflammatory response may prove fatal.
Christine Hanssen Rinaldo +2 more
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Progressive multifocal leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy (PML) was a rare disease until the advent of the HIV/AIDS pandemic. Recent interest in the disorder has been spurred by its appearance in patients treated with the monoclonal antibodies natalizumab and rituximab.
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Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment.
Nicolas Lambert +4 more
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The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
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Asymptomatic progressive multifocal leukoencephalopathy: a case report and review of the literature
Background We report the development of asymptomatic progressive multifocal leukoencephalopathy in a patient with multiple sclerosis on natalizumab therapy.
Yinan Zhang +2 more
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Cerebral lesions in hematological malignancies: a case report
Background Progressive multifocal leukoencephalopathy is a rare central nervous system disease, resulting from reactivation of latent John Cunningham virus.
Nicoletta D’Ettore +3 more
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Progressive Multifocal Leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating disease with significant morbidity and mortality and no effective, targeted therapies. It is most often observed in association with abnormalities of cell-mediated immunity, in particular human immunodeficiency virus (HIV) infection, but also occurs in association with ...
Adang, Laura, Berger, Joseph
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