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Progressive multifocal leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus.
Joseph R Berger
exaly +7 more sources
Progressive Multifocal Leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the ...
Elena Grebenciucova, Joseph R Berger
exaly +9 more sources
Progressive multifocal leukoencephalopathy
doi:10.3969/j.issn.1672⁃6731.2020.03 ...
Xiao⁃ling YAN
doaj +2 more sources
Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient [PDF]
Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients.
Krisztina K. Johansen +3 more
doaj +3 more sources
Progressive multifocal leukoencephalopathy [PDF]
A 58-year-old woman admitted to the hospital had a 3-month history of progressive neurologic deterioration characterized by severe global aphasia and bilateral limb weakness, greater on the right. The patient had a 10-year history of systemic lupus erythematosus (SLE). Polyarthritis had been present for 6 weeks before the …
Henderson, R. D. +3 more
openaire +3 more sources
The still under-investigated role of cognitive deficits in PML diagnosis [PDF]
Background: Despite cognitive deficits frequently represent the first clinical manifestations of Progressive Multifocal Leukoencephalopathy (PML) in Natalizumab-treated MS patients, the importance of cognitive deficits in PML diagnosis is still under ...
Amato, Maria Pia +49 more
core +4 more sources
Background Progressive multifocal leukoencephalopathy is a rare demyelinating disease that is often secondary to lytic destruction of oligodendrocytes and, to a lesser extent, to astrocytes’ response to human neurotrophic John Cunningham polyomavirus ...
Sima Bahrami +6 more
doaj +1 more source
Background Progressive multifocal leukoencephalopathy is a rare disease, but the prognosis is very poor, especially in the immunosuppressed state with a non-HIV background, and there is no established treatment.
Neri Sone +13 more
doaj +1 more source
Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi +51 more
core +6 more sources
AIDS-related progressive multifocal leukoencephalopathy
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão +5 more
doaj +1 more source

