Results 1 to 10 of about 711,937 (246)

Progressive multifocal leukoencephalopathy [PDF]

Romanian Journal of Neurology, 2008
Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus.
Rosca Elena Cecilia, Mihaela Simu, Ruxandra Dana Chirileanu, M. Bednar, Ovidiu Rosca   +4 more
doaj   +10 more sources

Progressive multifocal leukoencephalopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
doi：10.3969/j.issn.1672⁃6731.2020.03 ...
Xiao⁃ling YAN
doaj   +3 more sources

Progressive Multifocal Leukoencephalopathy [PDF]

Neurologic Clinics, 2018
Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the ...
Joseph Robert Berger, Elena Grebenciucova   +1 more
exaly   +9 more sources

Progressive multifocal leukoencephalopathy [PDF]

Tidsskrift for Den norske legeforening, 2017
Progressive multifocal leukoencephalopathy is a rare, opportunistic infection of the central nervous system caused by the John Cunningham virus (JCV). There is no effective antiviral treatment available, and restoring immunocompetence is essential for survival. If this occurs too quickly, however, the inflammatory response may prove fatal.
Christine Hanssen Rinaldo, Kjell-Morten Myhr, Karl Bjørnar Alstadhaug   +2 more
openaire   +3 more sources

JC Polyomavirus, progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome: a review

AIDS Research and Therapy, 2020
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat, Yihong Zhou, Shengquan Tang, Yaokai Chen   +3 more
doaj   +2 more sources

Natalizumab-associated progressive multifocal leukoencephalopathy

Frontiers in Neurology
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain resulting from infection of oligodendrocytes by JC virus (JCV) typically occurring in association with defects of cell-mediated immunity.
Trevor Glenn, Joseph R. Berger, Caleb R. S. McEntire   +2 more
doaj   +2 more sources

Prolonged Headache in a 13-Year-Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin. [PDF]

Clin Case Rep
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Hadizadeh A, Esfahani H, Hosseini F, Fayyazi A, Ghalandari N.   +4 more
europepmc   +2 more sources

A case of progressive multifocal leukoencephalopathy in an adult patient with ADA-SCIDPML in ADA-SCID [PDF]

Journal of Human Immunity
This case report describes progressive multifocal leukoencephalopathy in a patient with ADA-SCID status after gene therapy. Persistent metabolic dysfunction likely contributed to JC virus reactivation, highlighting this rare complication of ADA-SCID and ...
Hannah Shin, Lori Broderick, Jessica Azevedo, Caitlin Mulligan, Kari Hird, Vanessa Goodwill, Courtney Parkin, Stephanie Mortensen, Madisen Traveller, Ahmad Rayes, John Bohnsack, Donald B. Kohn, Teresa K. Tarrant, Michael Hershfield, Jonathan J. Lyons   +14 more
doaj   +2 more sources

Progressive Multifocal Leukoencephalopathy Treated by Immune Checkpoint Inhibitors

Annals of Neurology, 2022
Our aim was to assess the real‐world effectiveness of immune checkpoint inhibitors for treatment of patients with progressive multifocal leukoencephalopathy (PML).
X. Boumaza, Baptiste Bonneau, D. Roos-weil, C. Pinnetti, S. Rauer, L. Nitsch, A. Del Bello, I. Jelcic, K. Sühs, J. Gasnault, Yasemin Goreci, O. Grauer, S. Gnanapavan, R. Wicklein, N. Lambert, T. Perpoint, M. Beudel, D. Clifford, A. Sommet, I. Cortese, G. Martin-Blondel   +20 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy: epidemiology and spectrum of predisposing conditions.

Brain : a journal of neurology, 2022
Population-based data on the epidemiology of progressive multifocal leukoencephalopathy, its predisposing conditions and mortality rate are lacking, although such data are crucial to raise awareness among clinicians and to lay foundations for future ...
M. Joly, C. Conte, C. Cazanave, V. Le Moing, P. Tattevin, P. Delobel, A. Sommet, G. Martin-Blondel   +7 more
semanticscholar   +1 more source