Results 11 to 20 of about 10,390 (175)
Acta Médica Portuguesa, 2015 Introduction: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection ...
Luís Augusto +4 more
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Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
Emerging Infectious Diseases, 2022 Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment.
Nicolas Lambert +4 more
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Progressive multifocal leukoencephalopathy [PDF]
Current Neurology and Neuroscience Reports, 2000 Progressive multifocal leukoencephalopathy (PML) was a rare disease until the advent of the HIV/AIDS pandemic. Recent interest in the disorder has been spurred by its appearance in patients treated with the monoclonal antibodies natalizumab and rituximab.
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AIDS Research and Therapy, 2020 The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
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Asymptomatic progressive multifocal leukoencephalopathy: a case report and review of the literature
Journal of Medical Case Reports, 2018 Background We report the development of asymptomatic progressive multifocal leukoencephalopathy in a patient with multiple sclerosis on natalizumab therapy.
Yinan Zhang +2 more
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Cerebral lesions in hematological malignancies: a case report
Journal of Medical Case Reports, 2021 Background Progressive multifocal leukoencephalopathy is a rare central nervous system disease, resulting from reactivation of latent John Cunningham virus.
Nicoletta D’Ettore +3 more
doaj +1 more source
Progressive Multifocal Leukoencephalopathy [PDF]
F1000Research, 2015 Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating disease with significant morbidity and mortality and no effective, targeted therapies. It is most often observed in association with abnormalities of cell-mediated immunity, in particular human immunodeficiency virus (HIV) infection, but also occurs in association with ...
Adang, Laura, Berger, Joseph
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PARP-1 deregulation in multiple sclerosis
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019 Background Poly (ADP-ribose) polymerase 1 (PARP-1) plays pivotal roles in immune and inflammatory responses. Accumulating evidence suggests PARP-1 as a promising target for immunomodulation in multiple sclerosis and natalizumab-associated progressive ...
Maria Meira +8 more
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International Journal of Infectious Diseases, 2023 This report presents the case of a 47-year-old male patient who worked as a mathematics teacher and experienced the sudden onset of disorientation, aphasia, and acalculia during an online class.
Yago Marcos Pessoa-Gonçalves +10 more
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Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab
Emerging Infectious Diseases, 2018 Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore ...
Martin Martinot +7 more
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