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Arquivos de Neuro-Psiquiatria, 2023 Background Progressive multifocal leukoencephalopathy (PML) - immune reconstitution inflammatory syndrome (IRIS) in people living with HIV/AIDS (PLWHA) has been rarely described in low- and middle-income countries.
Monize Nascimento Santana +5 more
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Progressive multifocal leukoencephalopathy: new concepts
Arquivos de Neuro-Psiquiatria, 2013 Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the CNS caused by reactivation of JC virus (JCV) in a setting of cellular immunosuppression.
Marco A. Lima
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Treatment of progressive multifocal leukoencephalopathy [PDF]
Journal of Neurology, 2019 Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease of the central nervous system caused by John Cunningham polyomavirus (JCV), a globally seroprevelant virus that commonly causes a silent or benign infection. However, in immunocompromised patients JCV can be reactivated. In this situation, most organs remain
Castle, Daniel, Robertson, Neil P.
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Progressive multifocal leukoencephalopathy: rheumatological aspects
Современная ревматология, 2015 Progressive multifocal leukoencephalopathy (PML) is a severe progressive viral disease that affects the central nervous system in patients with immunodeficiency.
Boris Sergeevich Belov
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Progressive multifocal leukoencephalopathy treated with interleukin-7
Clinical Infection in Practice, 2020 Background: Progressive multifocal leukoencephalopathy (PML) is a rare devastating brain infection caused by the JC polyomavirus (JCPyV) in patients with impaired cellular immune responses. In the absence of effective anti-viral therapy, it is unclear if
Karl B. Alstadhaug +4 more
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Smoldering myeloma presenting as progressive multifocal leukoencephalopathy: a case report
Journal of Medical Case Reports, 2012 Introduction Progressive multifocal leukoencephalopathy is an opportunistic infection occurring in patients with severe cellular immunodeficiency. This case highlights the role of cellular immunodeficiency in the reactivation of John Cunningham virus in ...
Troppmann Martina +3 more
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Immunology of progressive multifocal leukoencephalopathy [PDF]
Journal of NeuroVirology, 2015 The high prevalence of asymptomatic JC polyomavirus (JCV) infection in the general population indicates coexistence with the human host and efficient immune control in healthy individuals. For unknown reasons, kidney-resident archetypic JCV strains can turn into neurotropic JCV strains which in hereditary or acquired states of immunodeficiency cause ...
Jelcic, Ivan +4 more
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The Modern Value of Clinical Autopsies
Acta Médica Portuguesa, 2015 Keywords: Autopsy; Antiretroviral Therapy, Highly Active; HIV Infections; Leukoencephalopathy, Progressive Multifocal.
Carlos Marques Pontinha
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Rituximab-Associated Inflammatory Progressive Multifocal Leukoencephalopathy
Case Reports in Infectious Diseases, 2016 Progressive multifocal leukoencephalopathy (PML) is a rare disease of the immunosuppression that results from neurotropic invasion of the JC virus which leads to demyelination of oligodendrocytes.
Chandra Punch +2 more
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Myoclonus as an unusual presentation of progressive multifocal leukoencephalopathy in a HIV positive patient [PDF]
Romanian Journal of Neurology, 2012 From mild muscular contractions to gross jerks affecting the whole body, myoclonus is an involuntary movement caused by an excessive discharge from a group of neurons located in one or multiple sites from cortical to peripheral level.
Lucian Chicea +4 more
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