Results 21 to 30 of about 711,937 (246)

Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient [PDF]

Case Reports in Neurology, 2013
Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients.
Krisztina K. Johansen, Sverre H. Torp, Jana Rydland, Jan O. Aasly   +3 more
doaj   +3 more sources

Multifocal Leukoencephalopathy

Pediatric Neurology Briefs, 1994
A 15-year-old boy with Wiskott-Aldrich syndrome complicated by progressive multifocal leukoencephalopathy (PML) is reported from the University of Miami School of Medicine, FL, and the National Institute of Neurological Disorders and Stroke, Bethesda, MD.
J Gordon Millichap
doaj   +2 more sources

Remission of progressive multifocal leukoencephalopathy following highly active antiretroviral therapy in a man with AIDS

International Journal of General Medicine, 2012
Katie Yoganathan1, David Brown2, Kathir Yoganathan31Cardiff Medical School, Cardiff, Wales, UK; 2Virus Reference Department, Microbiology Services, Health Protection Agency, London, UK; 3Singleton Hospital, Abertawe Bro Morgannwg University Health Board,
Yoganathan K, Brown D, Yoganathan K
doaj   +1 more source

Disease-modifying therapies and progressive multifocal leukoencephalopathy in multiple sclerosis: A systematic review and meta-analysis

Journal of Neuroimmunology, 2021
Background High efficacy disease modifying therapies (DMT) in the management of Multiple Sclerosis (MS) have a favorable effect on relapse rate and disability progression; however, they can expose patients to significant risks, such as progressive ...
Shitiz Sriwastava, Saurabh Kataria, Samiksha Srivastava, Shaghayegh Kazemlou, Si Gao, S. Wen, H. Saber, R. Tripathi, Zubeda B. Sheikh, S. Peterson, R. Gwinn, E. Bernitsas   +11 more
semanticscholar   +1 more source

Progressive Multifocal Leukoencephalopathy in a Patient With Progressive Multiple Sclerosis Treated With Ocrelizumab Monotherapy.

JAMA Neurology, 2021
Importance Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection caused by the JC virus that has no proven effective treatment.
Arpan Patel, J. Sul, M. Gordon, J. Steinklein, S. Sanguinetti, B. Pramanik, D. Purohit, V. Haroutunian, Alex K. Williamson, I. Koralnik, A. Harel   +10 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy [PDF]

Neurology, 2002
A 58-year-old woman admitted to the hospital had a 3-month history of progressive neurologic deterioration characterized by severe global aphasia and bilateral limb weakness, greater on the right. The patient had a 10-year history of systemic lupus erythematosus (SLE). Polyarthritis had been present for 6 weeks before the …
Henderson, R. D., Smith, M. G., Mowat, P., Read, S. J.   +3 more
openaire   +4 more sources

Adoptive Transfer of JC Virus‐Specific T Lymphocytes for the Treatment of Progressive Multifocal Leukoencephalopathy

Annals of Neurology, 2021
Progressive multifocal leukoencephalopathy (PML) is still burdened by high mortality in a subset of patients, such as those affected by hematological malignancies.
G. Berzero, S. Basso, L. Stoppini, A. Palermo, A. Pichiecchio, M. Paoletti, Federica Lucev, S. Gerevini, A. Rossi, E. Vegezzi, L. Diamanti, P. Bini, M. Gastaldi, S. Delbue, C. Perotti, E. Seminari, M. Faraci, M. Luppi, F. Baldanti, M. Zecca, E. Marchioni, P. Comoli   +21 more
semanticscholar   +1 more source

Advances in Treatment of Progressive Multifocal Leukoencephalopathy

Annals of Neurology, 2021
Progressive multifocal encephalopathy (PML) is a severe demyelinating disease of the central nervous system (CNS) caused by JC virus (JCV), which occurs in immunocompromised individuals. Management of PML relies on restoration of immunity within the CNS.
R. Bernard-Valnet, I. Koralnik, R. Du Pasquier   +2 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy in a patient with novel mutation in the RAC2 gene: a case report

Journal of Medical Case Reports, 2022
Background Progressive multifocal leukoencephalopathy is a rare demyelinating disease that is often secondary to lytic destruction of oligodendrocytes and, to a lesser extent, to astrocytes’ response to human neurotrophic John Cunningham polyomavirus ...
Sima Bahrami, Saba Arshi, Mohammad Nabavi, Mohammad Hassan Bemanian, Morteza Fallahpour, Afshin Rezaeifar, Sima Shokri   +6 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease

Nature Reviews Neurology, 2020
Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic infection in the general population. Emerging evidence that PML can be ameliorated
I. Cortese, D. Reich, A. Nath
semanticscholar   +1 more source