Results 51 to 60 of about 10,287 (171)

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2162-2170, July 2026.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy in a child with acquired immunodeficiency syndrome (AIDS) Leucoencefalopatia multifocal progressiva em uma criança com síndrome da imunodeficiênda adquirida

Arquivos de Neuro-Psiquiatria, 1997
Progressive multifocal leukoencephalopathy is a rare viral-induced demyelinating disease associated to immunodeficiency. A 10-year-old boy with AIDS is reported, who developed subacute cerebellar signs and symptoms with multiple cranial nerve involvement
Alexandra Prufer de Q.C. Araujo, Heloisa S. Pereira, Ricardo H. Oliveira, Ana C. Frota, José C. Esperança, Francisco Duarte   +5 more
doaj   +1 more source

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

Journal of Gastroenterology and Hepatology, Volume 41, Issue 7, Page 2006-2029, July 2026.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi, Khoon Lin Ling, Julajak Limsrivilai, Shu‐Chen Wei, Joyce Wing Yan Mak, Taku Kobayashi, Luan Minh Dang, Rupert W. Leong, Huiyu Lin, Meng‐Tzu Weng, Wan Chee Ong, Vineet Ahuja, Satimai Aniwan, Ryota Hokari, Wei Jie Jonathan Lee, Alex Hwong‐Ruey Leow, Wai‐Keung Leung, Wee‐Chian Lim, Govind Makharia, Katsuyoshi Matsuoka, Nazri Mustaffa, Siew‐Chien Ng, Mathew Philip, Pises Pisespongsa, Raja Affendi Raja Ali, Zhi Hua Ran, Marcellus Simadibrata, Jose Sollano, Malcolm Tan, Hang Dao Viet, Nik Razima Wan Ibrahim, Kai Chun Wu, Byong Duk Ye, Ida Hilmi, Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease Committee and Asian Education Network in IBD (AEN‐IBD)   +34 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

International Journal of General Medicine, 2009
Melissa G Ooi1, Peter J Kelly2, Michael Farrell3, Philip Murphy4, Peter O’Gorman11Department of Hematology; 2Department of Neurology, Mater Misericordiae Hospital, Dublin, Ireland; 3Department of Neuropathology; 4Department of Hematology ...
Melissa G Ooi, Peter J Kelly, Michael Farrell, Philip Murphy, Peter O’Gorman   +4 more
doaj  

Progressive multifocal leukoencephalopathy (PML)

Rinsho Shinkeigaku, 2011
Progressive multifocal leukoencephalopathy (PML) is caused by reactivation of latently infected JCV when hosts' immune system is impaired by HIV infection, hematologic diseases, collagen diseases, immunemodulatory therapy and so on. PML was rare but HIV infection and Natalizumab have made it much more common while the prognosis is much better than ...
Mizusawa, Hidehiro, Kishida, Shuji, Saijo, Masayuki, Yukishita, Motohiro, Shishido-Hara, Yukiko, Sawa, Hirohumi, Nagashima, Kazuo, Nukuzuma, Souichi, Yamada, Masahito   +8 more
openaire   +3 more sources

Natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS): “a case report from Ireland with review of literature, clinical pitfalls and future direction”

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Progressive multifocal leukoencephalopathy (PML) is one of the most serious treatment-related complications that is encountered in patients with multiple sclerosis (MS).
Salman Mansoor, Gerard Mullane, Mohammad Hijaz Adenan, Siobhan Kelly, Aine Water, Grainne McPartland, Kevin Murphy   +6 more
doaj   +1 more source

Adult‐onset CD8‐predominant hemispheric inflammatory epilepsy: Expanding the spectrum of post‐infectious and Rasmussen‐like encephalitis

Epileptic Disorders, EarlyView.
Ramya Raghupathi
wiley   +1 more source

Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis

Case Reports in Radiology, 2013
Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal ...
Guglielmo Manenti, Simone Altobelli, Marco Nezzo, Marco Antonicoli, Erald Vasili, Luca Neroni, Roberto Floris, Giovanni Simonetti   +7 more
doaj   +1 more source

The Effect of Ocrelizumab on Anti‐JC Virus Antibody Index

Brain and Behavior, Volume 16, Issue 5, May 2026.
Synopsis: This study of 553 MS patients found that anti‐JC virus (JCV) antibody indices remain stable during the first 2 years of ocrelizumab treatment. While peripheral B‐cells were significantly depleted and serum immunoglobulins (IgG, IgM, IgA) showed modest declines, the JCV antibody index did not change significantly.
Akash Virupakshaiah, Alexander J. Gill, Vinicius A. Schoeps, Emma Wilson, James Wilson, David Do, Amit Bar‐Or, Dina Jacobs, Joseph R. Berger   +8 more
wiley   +1 more source

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY: A CASE REPORT

Brazilian Journal of Infectious Diseases
Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease that severely affects the central nervous system (CNS) through the JC polyomavirus.
Bruna Kochhann Menezes, Viviane Raquel Buffon, Larissa Gregolin Stoker, Luiza Maria Bertarello, Luiza Peixoto Barbieri   +4 more
doaj   +1 more source