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Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System. [PDF]
Front Genet, 2019 Background: Diseases of the nervous system are widely considered to be caused by genetic mutations, and they have been shown to share pathogenic genes. Discovering the shared mechanisms of these diseases is useful for designing common treatments. Method:
Qi M +12 more
europepmc +2 more sources
Actin and Diseases of the Nervous System. [PDF]
Adv Neurobiol, 2011 Abnormal regulation of the actin cytoskeleton results in several pathological conditions affecting primarily the nervous system. Those of genetic origin arise during development, but others manifest later in life. Actin regulation is also affected profoundly by environmental factors that can have sustained consequences for the nervous system.
Bernstein BW, Maloney MT, Bamburg JR.
europepmc +3 more sources
Notes on diseases of the nervous system
Lancet, The, 1886 NOTES ON DISEASES OF THE NERVOUS SYSTEM Notes on diseases of the nervous system (1) (-
Gowers, W. R.
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Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 [PDF]
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
GBD 2021 Nervous System Disorders Collaborators +1 more
core +10 more sources
Infectious Diseases of the Nervous System [PDF]
Atlas of Clinical Neurology, 2011 The curriculum for child neurology trainees should include information regarding the many infectious and post-infectious disorders that affect the developing nervous system. This article provides recommendations regarding the nature of the educational content and suggestions how this content can be provided to trainees.
europepmc +3 more sources
Journal of Experimental & Clinical Cancer Research, 2023 Background After diagnosis, glioblastoma (GBM) patients undertake tremendous psychological problems such as anxiety and depression, which may contribute to GBM progression.
Yan Wang +10 more
doaj +1 more source
Cell Death and Disease, 2021 Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing ...
Guanzheng Liu +13 more
doaj +1 more source
BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas
Cancer Biology & Medicine, 2021 Objective: BYSL, which encodes the Bystin protein in humans, is upregulated in reactive astrocytes following brain damage and/or inflammation. We aimed to determine the role and mechanism of BYSL in glioma cell growth and survival.
Shangfeng Gao +8 more
doaj +1 more source
Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
Frontiers in Oncology, 2021 Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy,
Yandong Xie +12 more
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Frontiers in Oncology, 2021 Glioblastoma multiforme (GBM) is a devastating disease yet no effective drug treatment has been established to date. Glioblastoma stem-like cells (GSCs) are insensitive to treatment and may be one of the reasons for the relapse of GBM. Maternal embryonic
Xu Zhang +16 more
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