Results 21 to 30 of about 246,068 (262)

Construction and validation of a risk model based on the key SNARE proteins to predict the prognosis and immune microenvironment of gliomas

Frontiers in Molecular Neuroscience, 2023
BackgroundSynaptic transmission between neurons and glioma cells can promote glioma progression. The soluble N-ethylmaleimide-sensitive fusion factor attachment protein receptors (SNARE) play a key role in synaptic functions.
Luxin Yin, Luxin Yin, Yiqiang Xu, Yiqiang Xu, Jiale Yin, Hai Cheng, Weihan Xiao, Yue Wu, Yue Wu, Daofei Ji, Daofei Ji, Shangfeng Gao, Shangfeng Gao   +12 more
doaj   +1 more source

Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases [PDF]

, 2019
Many drugs have been designed to treat diseases of the central nervous system (CNS), especially neurodegenerative diseases. However, the presence of tight junctions at the blood-brain barrier has often compromised the efficiency of drug delivery to ...
Ling, King Hwa, Mohamed, Farahidah, Mansor, Nur Izzati, Rosli, Rozita, Nordin, Norshariza, Ling, King-Hwa, Hassan, Zurina   +6 more
core   +1 more source

Diseases of the Peripheral Nervous System

, 2022
With the rapid development of information technology in the world today, many new symptoms of many diseases are being identified. Especially in this regard, much higher results are being achieved in diseases of the nervous system.
Khodjaeva Gulnora Abdubannonovna, assistant
core   +1 more source

UBA1 inhibition contributes radiosensitization of glioblastoma cells via blocking DNA damage repair

Frontiers in Pharmacology, 2023
Glioblastoma multiforme (GBM) is a brain tumor with high mortality and recurrence rate. Radiotherapy and chemotherapy after surgery are the main treatment options available for GBM. However, patients with glioblastoma have a grave prognosis.
Changyong Wu, Changyong Wu, Yang Shen, Yang Shen, Lin Shi, Lin Shi, Lin Shi, Junhao Zhang, Tongxuan Guo, Lingni Zhou, Wanzhou Wang, Xu Zhang, Xu Zhang, Rutong Yu, Rutong Yu, Xuejiao Liu, Xuejiao Liu   +16 more
doaj   +1 more source

Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair. [PDF]

, 2021
Peptidylarginine deiminases are a family of calcium-activated enzymes with multifaceted roles in physiological and pathological processes, including in the central nervous system.
Lange, Sigrun
core   +1 more source

Bolaamphiphiles as a novel drug delivery system in the treatment of diseases of the brain [PDF]

, 2020
The incidence of central nervous system (CNS) diseases, such as glioblastoma, Alzheimer’s disease and Parkinson’s disease, will increase substantially in the next few decades. However, treatment for diseases of the brain is limited due to the restrictive
Maclatchy, A.
core   +1 more source

Infectious Diseases (esp. Equatorial): Infections of the Nervous System

, 2022
Microbes, the most prevalent organisms on Earth, are essential parts of all ecosystems. We are all exposed to microbes in the environment and harbor them.
Kristensson, K, Rottenberg, M, Bentivoglio, M   +2 more
core   +1 more source

High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma

Journal of Experimental & Clinical Cancer Research, 2017
Background Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis. However, there are no effective targeted therapies for glioma patients.
Chenglong Yue, Mingshan Niu, Qian Qian Shan, Ting Zhou, Yiming Tu, Peng Xie, Lei Hua, Rutong Yu, Xuejiao Liu   +8 more
doaj   +1 more source

ON THE STUDY OF DISEASES OF THE NERVOUS SYSTEM. [PDF]

Brain, 1903
n ...
openaire   +2 more sources

Overview of neglected tropical diseases and conditions of the nervous system: past, present and perspectives.

, 2014
Neglected tropical diseases consist of a group of infectious diseases with the unifying features of being poverty-related, prevalent in tropical and subtropical regions, and absent from the public health agenda in wealthy countries.
BENTIVOGLIO FALES, Marina, Esper A. Cavalheiro, Kristensson K., Cavalheiro E. A., Nilesh B. Patel, Patel N. B., Krister Kristensson, Marina Bentivoglio   +7 more
core   +1 more source