Results 11 to 20 of about 181,905,299 (309)

Actin and Diseases of the Nervous System. [PDF]

open access: yesAdv Neurobiol, 2011
Abnormal regulation of the actin cytoskeleton results in several pathological conditions affecting primarily the nervous system. Those of genetic origin arise during development, but others manifest later in life. Actin regulation is also affected profoundly by environmental factors that can have sustained consequences for the nervous system.
Bernstein BW, Maloney MT, Bamburg JR.
europepmc   +3 more sources

Infectious Diseases of the Nervous System [PDF]

open access: yesAtlas of Clinical Neurology, 2011
The curriculum for child neurology trainees should include information regarding the many infectious and post-infectious disorders that affect the developing nervous system. This article provides recommendations regarding the nature of the educational content and suggestions how this content can be provided to trainees.
europepmc   +3 more sources

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 [PDF]

open access: yes
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
GBD 2021 Nervous System Disorders Collaborators   +1 more
core   +7 more sources

Chronic stress accelerates glioblastoma progression via DRD2/ERK/β-catenin axis and Dopamine/ERK/TH positive feedback loop

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
Background After diagnosis, glioblastoma (GBM) patients undertake tremendous psychological problems such as anxiety and depression, which may contribute to GBM progression.
Yan Wang   +10 more
doaj   +1 more source

RETRACTED ARTICLE: GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death

open access: yesCell Death and Disease, 2021
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing ...
Guanzheng Liu   +13 more
doaj   +1 more source

Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System. [PDF]

open access: yesFront Genet, 2019
Background: Diseases of the nervous system are widely considered to be caused by genetic mutations, and they have been shown to share pathogenic genes. Discovering the shared mechanisms of these diseases is useful for designing common treatments. Method:
Qi M   +12 more
europepmc   +2 more sources

BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas

open access: yesCancer Biology & Medicine, 2021
Objective: BYSL, which encodes the Bystin protein in humans, is upregulated in reactive astrocytes following brain damage and/or inflammation. We aimed to determine the role and mechanism of BYSL in glioma cell growth and survival.
Shangfeng Gao   +8 more
doaj   +1 more source

Targeting sialylation to treat central nervous system diseases. [PDF]

open access: yes, 2021
Sialic acid-binding immunoglobulin-type lectins (SIGLECs) are membrane receptors that are preferentially expressed on immune cells and recognize sialylated proteins, lipids, and RNA.
Neumann, Harald   +2 more
core   +1 more source

Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma

open access: yesFrontiers in Oncology, 2021
Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy,
Yandong Xie   +12 more
doaj   +1 more source

Diseases of the Peripheral Nervous System [PDF]

open access: yes, 2022
With the rapid development of information technology in the world today, many new symptoms of many diseases are being identified. Especially in this regard, much higher results are being achieved in diseases of the nervous system.
Khodjaeva Gulnora Abdubannonovna, assistant
core   +1 more source

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