Results 1 to 10 of about 194,510 (268)
Frontiers in Neurology, 2023 ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported.
Chuan-bao Zhang +9 more
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Extracranial metastasis of anaplastic oligoastrocytoma
Cancer Biology & Medicine, 2018 Extracranial metastasis (ECM) of glioma is a rare condition that occurs in the internal nervous axis. A 23-year-old woman presented with anaplastic oligoastrocytoma (WHO III) in a left temporal tumor.
Zhuang Kang +8 more
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Weighted correlation network analysis identifies multiple susceptibility loci for low‐grade glioma
Cancer Medicine, 2023 Background The current molecular classifications cannot completely explain the polarized malignant biological behavior of low‐grade gliomas (LGGs), especially for tumor recurrence.
Xiaodong Niu +8 more
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SAMD9 Is Relating With M2 Macrophage and Remarkable Malignancy Characters in Low-Grade Glioma
Frontiers in Immunology, 2021 Immunoreactions regulated by TAMs (Tumor-associated macrophages) play a pivotal role in tumorigenesis and metastasis. In recent decades, treatments based on immune regulation have achieved revolutionary breakthroughs in cancer targeted therapies.
Wenping Ma +14 more
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BMC Cancer, 2020 Background Glioblastomas (GBM) are therapy-resistant tumors with a profoundly immunosuppressive tumor microenvironment. Chemotherapy has shown limited efficacy against GBM.
Julio Enríquez Pérez +4 more
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Cells, 2022 Current treatments for lower-grade glioma (LGG) do not effectively improve life expectancy rates, and this is a major global health concern. Improving our knowledge of this disease will ultimately help to improve prevention, accurate prognosis, and ...
Yongze He +6 more
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Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH-mutant glioblastoma
Cancer Biology & Medicine, 2021 Objective: O6methylguanine-DNA methyltransferase (MGMT) promoter methylation is a biomarker widely used to predict the sensitivity of IDH-wildtype glioblastoma to temozolomide therapy.
Ruichao Chai +11 more
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TMEFF2 promoter hypermethylation is an unfavorable prognostic marker in gliomas
Cancer Cell International, 2021 Background Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) is a transmembrane protein in the tomoregulin family. Little research has been performed to determine whether TMEFF2 methylation is a prognostic marker in adult ...
Sidi Xie +10 more
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Frontiers in Oncology, 2022 Metabolic reprogramming is a hallmark of glioma, and sterol O-acyltransferase 1 (SOAT1) is an essential target for metabolic therapy. However, the prognostic value of SOAT1 and its association with immune infiltration has not been fully elucidated. Using
Xuyang Guo +13 more
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Gene Expression Profiling Stratifies IDH-Wildtype Glioblastoma With Distinct Prognoses
Frontiers in Oncology, 2019 Objectives: In the present study, we aimed to determine the candidate genes that may function as biomarkers to further distinguish patients with isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM), which are heterogeneous with respect to clinical ...
Yu-Qing Liu +13 more
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