Results 31 to 40 of about 382,034 (365)

St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity [PDF]

, 2021
Ganglioside GD3/GD2 are over-expressed in various neuroectoderm-derived tumors. Previous studies indicated that GD3 is involved in the enhancement of cancer properties such as rapid growth and increased invasiveness.
Ohkawa, Yuki, Yamamoto, Satoko, Furukawa, Keiko, Kato, Akira, Natsume, Atsushi, Momota, Hiroyuki, Furukawa, Koichi, Farhana, Yesmin, Wakabayashi, Toshihiko, Bhuiyan, Robiul H., Kaneko, Kei, Okajima, Tetsuya, Ohmi, Yuhsuke, Zhang, Pu   +13 more
core   +1 more source

TMEFF2 promoter hypermethylation is an unfavorable prognostic marker in gliomas

Cancer Cell International, 2021
Background Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) is a transmembrane protein in the tomoregulin family. Little research has been performed to determine whether TMEFF2 methylation is a prognostic marker in adult ...
Sidi Xie, Yunxiao Zhang, Tao Peng, Jinglin Guo, Yongfu Cao, Jing Guo, Xiaofeng Shi, Yaqin Li, Yawei Liu, Songtao Qi, Hai Wang   +10 more
doaj   +1 more source

Receptors for hyaluronic acid and poliovirus: a combinatorial role in glioma invasion? [PDF]

, 2012
BACKGROUND: CD44 has long been associated with glioma invasion while, more recently, CD155 has been implicated in playing a similar role. Notably, these two receptors have been shown closely positioned on monocytes.
James R Smith, Zaynah Maherally, Geoffrey J Pilkington, Maherally, Zaynah, Qian An, Pilkington, Geoff, An Qian, Pilkington Geoffrey J., An, Qian, Smith James R., Smith, James, Maherally Zaynah   +11 more
core   +1 more source

Comprehensive Analysis of Sterol O-Acyltransferase 1 as a Prognostic Biomarker and Its Association With Immune Infiltration in Glioma

Frontiers in Oncology, 2022
Metabolic reprogramming is a hallmark of glioma, and sterol O-acyltransferase 1 (SOAT1) is an essential target for metabolic therapy. However, the prognostic value of SOAT1 and its association with immune infiltration has not been fully elucidated. Using
Xuyang Guo, Xuyang Guo, Shaolong Zhou, Shaolong Zhou, Zhuo Yang, Zhuo Yang, Zi-An Li, Zi-An Li, Weihua Hu, Lirui Dai, Lirui Dai, Wulong Liang, Xinjun Wang, Xinjun Wang   +13 more
doaj   +1 more source

The molecular role of non-canonical Notch signaling via Deltex-1 in high grade glioma [PDF]

, 2011
Glioblastoma Multiforme is a WHO grade IV brain tumor with glial characteristics leading to more years of life lost than any other cancer. A better understanding of GBM biology and valid animal models are the two key elements to improved therapeutic ...
Huber, Roland Martin
core   +1 more source

Ferroptosis, as the most enriched programmed cell death process in glioma, induces immunosuppression and immunotherapy resistance.

Neuro-Oncology, 2022
BACKGROUND Immunosuppressive microenvironment is a major cause of immunotherapeutic resistance in glioma. In addition to secreting compounds, tumor cells under programmed cell death (PCD) processes release abundant mediators to modify the neighboring ...
Tianqi Liu, Chen Zhu, Xin Chen, Ge-fei Guan, Cunyi Zou, Shuai Shen, Jianqi Wu, Yuhang Wang, Zhiguo Lin, Ling Chen, Peng Cheng, Wen Cheng, Anhua Wu   +12 more
semanticscholar   +1 more source

Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma

Cell, 2016
SUMMARY Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic glioma driving alterations and suboptimal disease classification.
M. Ceccarelli, F. Barthel, T. Malta, Thais S. Sabedot, S. Salama, Bradley A. Murray, O. Morozova, Yulia Newton, Amie Radenbaugh, S. Pagnotta, Samreen Anjum, Jiguang Wang, G. Manyam, P. Zoppoli, Shiyun Ling, A. Rao, Mia Grifford, A. Cherniack, Hailei Zhang, L. Poisson, C. Carlotti, D. Tirapelli, A. Rao, T. Mikkelsen, C. Lau, W. Yung, R. Rabadán, J. Huse, D. Brat, N. Lehman, J. Barnholtz-Sloan, Siyuan Zheng, K. Hess, G. Rao, M. Meyerson, R. Beroukhim, Lee Cooper, Rehan Akbani, M. Wrensch, D. Haussler, K. Aldape, P. Laird, D. Gutmann, H. Noushmehr, A. Iavarone, R. Verhaak, H. Arachchi, J. Auman, M. Balasundaram, S. Balu, G. Barnett, Stephen Baylin, Sue Bell, C. Benz, Natalie Bir, K. Black, T. Bodenheimer, L. Boice, M. Bootwalla, Jay Bowen, C. Bristow, Y. Butterfield, Qingrong Chen, L. Chin, Juok Cho, E. Chuah, Sudha Chudamani, Simon G. Coetzee, M. Cohen, H. Colman, M. Couce, F. D’Angelo, Tanja Davidsen, Amy Davis, J. Demchok, K. Devine, Li Ding, R. Duell, J. Elder, J. Eschbacher, Ashley Fehrenbach, M. Ferguson, S. Frazer, Gregory G. Fuller, J. Fulop, S. Gabriel, L. Garofano, J. Gastier-Foster, Nils Gehlenborg, M. Gerken, G. Getz, C. Giannini, W. Gibson, Angela Hadjipanayis, D. Hayes, David I Heiman, B. Hermes, J. Hilty, K. Hoadley, A. Hoyle, Meijuan Huang, S. Jefferys, Corbin D. Jones, Steven J. M. Jones, Z. Ju, A. Kastl, A. Kendler, Jaegil Kim, R. Kucherlapati, Phillip H. Lai, M. Lawrence, Semin Lee, K. Leraas, T. Lichtenberg, Pei Lin, Yuexin Liu, Jia Liu, J. Ljubimova, Yiling Lu, Yussanne Ma, D. Maglinte, Harshad S. Mahadeshwar, M. Marra, Mary McGraw, Christopher M. McPherson, S. Meng, P. Mieczkowski, C. Miller, G. Mills, Richard A. Moore, Lisle E. Mose, A. Mungall, R. Naresh, Theresa Naska, L. Neder, M. Noble, Ardene Noss, B. O’Neill, Q. Ostrom, C. Palmer, A. Pantazi, Michael G Parfenov, P. Park, J. Parker, C. Perou, C. Pierson, T. Pihl, A. Protopopov, N. Ramirez, W. Rathmell, X. Ren, J. Roach, A. G. Robertson, G. Saksena, J. Schein, S. Schumacher, J. Seidman, Kelly Senecal, S. Seth, Hui Shen, Yan Shi, J. Shih, K. Shimmel, H. Sicotte, Suzanne Sifri, T. Silva, J. Simons, Rosy Singh, Tara J. Skelly, A. Sloan, H. Sofia, Matthew G. Soloway, Xingzhi Song, C. Sougnez, Camila Souza, S. Staugaitis, Huandong Sun, Charlie Sun, Donghui Tan, Jiabin Tang, Yufang Tang, L. Thorne, F. Trevisan, T. Triche, D. V. Berg, Umadevi Veluvolu, D. Voet, Yunhu Wan, Zhining Wang, R. Warnick, J. Weinstein, D. Weisenberger, M. Wilkerson, Felicia Williams, L. Wise, Yingli Wolinsky, Junyuan Wu, A. W. Xu, Lixing Yang, Liming Yang, Travis Zack, J. Zenklusen, Jianhua Zhang, Wei Zhang, Jiashan Zhang, E. Zmuda   +205 more
semanticscholar   +1 more source

Expression of RECK in endothelial cells of glioma: comparison with CD34 and VEGF expressions [PDF]

, 2012
Angiogenesis is thought to be involved in the progression of glioma grades, and reversion-inducing cysteine-rich protein with Kazal motifs (RECK) has been said to be involved in maturation of vessels.
Rahmah, Nunung Nur, Sakai, Keiichi, Sano, Kenji, Hongo, Kazuhiro   +3 more
core   +1 more source

Gene Expression Profiling Stratifies IDH-Wildtype Glioblastoma With Distinct Prognoses

Frontiers in Oncology, 2019
Objectives: In the present study, we aimed to determine the candidate genes that may function as biomarkers to further distinguish patients with isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM), which are heterogeneous with respect to clinical ...
Yu-Qing Liu, Yu-Qing Liu, Fan Wu, Fan Wu, Jing-Jun Li, Jing-Jun Li, Yang-Fang Li, Yang-Fang Li, Xing Liu, Xing Liu, Zheng Wang, Zheng Wang, Rui-Chao Chai, Rui-Chao Chai   +13 more
doaj   +1 more source

Comprehensive Analysis of the Clinical and Biological Significances of Endoplasmic Reticulum Stress in Diffuse Gliomas

Frontiers in Cell and Developmental Biology, 2021
BackgroundAs a critical organelle for protein and lipid synthesis, the dysfunction of endoplasmic reticulum has a significant impact on multiple biological processes of cells.
Ruoyu Huang, Ruoyu Huang, Ruoyu Huang, Guanzhang Li, Guanzhang Li, Guanzhang Li, Kuanyu Wang, Kuanyu Wang, Zhiliang Wang, Zhiliang Wang, Zhiliang Wang, Fan Zeng, Fan Zeng, Huimin Hu, Huimin Hu, Tao Jiang, Tao Jiang, Tao Jiang   +17 more
doaj   +1 more source