Results 1 to 10 of about 532,597 (317)

Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring

Scientific Reports
Gestational hypothyroxinemia (HTX) is associated with cognitive impairments and autism traits in offspring. However, the underlying mechanisms remain unclear.
Enrique González-Madrid, Ma. Andreina Rangel-Ramírez, María C. Opazo, Sebastián A. Espinoza, Daniela Elgueta, Gonzalo I. Cancino, Elena Mery, Álvaro O. Ardiles, Luisa F. Duarte, Jorge A. Soto, Leandro J. Carreño, Felipe Simon, Susan M. Bueno, Pablo A. González, Alexis M. Kalergis, Claudia A. Riedel   +15 more
doaj   +1 more source

Phase I/II Clinical Study of PRaG Regimen Combined With Intraperitoneal Infusion of PD-1 Inhibitor for Advanced Refractory Solid Tumors With Cancerous Ascites (PRaG4.0P Study)

Technology in Cancer Research & Treatment
Objective: The prognosis of malignant tumors with peritoneal metastases and cancerous ascites has generally been poor, with limited treatment options.
Yingying Xu MS, Yuehong Kong MS, Yifu Ma MS, Meiling Xu MS, Jiabao Yang MS, Junjun Zhang PhD, Rongzheng Chen MS, Guangqiang Chen MS, Zhihui Hong MS, Xiangrong Zhao MS, Chenyang Zhang MS, Pengfei Xing MS, Liyuan Zhang MD, Peifeng Zhao MS   +13 more
doaj   +1 more source

NEAT1_1 confers gefitinib resistance in lung adenocarcinoma through promoting AKR1C1-mediated ferroptosis defence

Cell Death Discovery
Gefitinib is one of the most extensively utilized epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for treating advanced lung adenocarcinoma (LUAD) patients harboring EGFR mutation.
Shuman Zhen, Yunlong Jia, Yan Zhao, Jiali Wang, Boyang Zheng, Tianxu Liu, Yuqing Duan, Wei Lv, Jiaqi Wang, Fan Xu, Yueping Liu, Yi Zhang, Lihua Liu   +12 more
doaj   +1 more source

The antitumor mechanism of immuno-flap treatment in a rat model of head and neck cancer

Cancer Immunology, Immunotherapy
Background Local recurrence after surgical resection is a major clinical challenge in patients with advanced head and neck cancer (HNC). We previously reported using transfer of a flap treated with dendritic cells (DCs) (“immuno-flap”) as a novel cancer ...
Hiroaki Mori, Yasuto Akiyama, Chie Maeda, Akari Kanematsu, Tadashi Ashizawa, Kazue Yamashita, Haruo Miyata, Akira Iizuka, Tomoatsu Ikeya, Yoshichika Yasunaga, Jun Araki   +10 more
doaj   +1 more source

TGF-β Decreases NK Cell Mobility and Cytotoxic Efficacy in Complex in vitro Models of the Leukemia Microenvironment

ImmunoTargets and Therapy
Veronika Švubová,1,2 Lucie Janstová,1 Marek Jedlička,1,2 Eva Mašínová,1,2 Jana Szabová,1 Tereza Feglarová,1 Kateřina Kuglerová,1 Veronika Bosáková,3,4 Barbora Brodská,1 Kristýna Boráková,5 David Kundrát,1 Iva Trsová,1,6 Martina ...
Švubová V, Janstová L, Jedlička M, Mašínová E, Szabová J, Feglarová T, Kuglerová K, Bosáková V, Brodská B, Boráková K, Kundrát D, Trsová I, Böhmová M, Kuželová K, Hrdý J, Gašová Z, Vydra J, Dostálová Merkerová M, Hortová-Kohoutková M, Frič J   +19 more
doaj  

Local immunotherapy for the treatment of cancer: scientific advances and clinical potential. [PDF]

J Immunother Cancer
Kaufman HL, de Gruijl TD.
europepmc   +1 more source

A complex immunological idiotypic network for maintenance of tolerance

Frontiers in Immunology, 2014
Véronique eTHOMAS-VASLIN, Véronique eTHOMAS-VASLIN, Véronique eTHOMAS-VASLIN   +2 more
doaj   +1 more source

Targeting B7-H3 in patients with metastatic triple-negative breast cancer and brain metastases: an opportunity to "revive" immunotherapy as a treatment strategy? [PDF]

J Immunother Cancer
Kojundzic I, Zatzman C, Belone Lopes J, Ramay R, Bayani J, Spears M, Jerzak KJ.   +6 more
europepmc   +1 more source

Comprehensive Review of Immunotherapy in Colorectal Cancer: From Mechanisms to Nursing Interventions. [PDF]

Immunotargets Ther
Zhu Q, Lai Y, Zhao J, Zhang Z, Cui X, Kou M.   +5 more
europepmc   +1 more source

Immunotherapy in HCC: aetiology matters. [PDF]

eGastroenterology
Ng IO, Lyu G.
europepmc   +1 more source