Results 1 to 10 of about 575,896 (292)

Melanoma [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2012
Melanoma is a relatively common neoplasm which is increasing in incidence. Melanoma appears as a variegated irregular maculopapular lesion usually on the skin, but possibly on mucosae, conjunctiva, orbit, nails and oesophagus. They may be black, brown,
Daniel G, Coit   +24 more
openaire   +4 more sources

TP63 is implicated in apoptotic dysregulation in melanoma [PDF]

open access: yes, 2010
PhDCutaneous melanoma is an aggressive malignancy accounting for 4% of skin cancers but 80% of all skin-cancer related deaths. Its incidence is rapidly rising and advanced disease is notoriously treatment-resistant.
Matin, Rubeta N H
core   +4 more sources

Melanoma [PDF]

open access: yesJournal of Surgical Oncology, 2019
AbstractCurrent recommendations by the United States Preventive Services Task Force do not support screening for skin cancer. Melanoma is unique among cancers because detection is through visual inspection. Development of technologies that aid visual inspection have supported screening strategies in high‐risk populations such as older fair skinned ...
Conor H. O'Neill, Charles R. Scoggins
openaire   +4 more sources

The effect of COVID-19 emergency in the management of melanoma in Italy

open access: yesDermatology Reports, 2021
The COVID-19 pandemic has severely hampered the functioning of any health system, absorbing a considerable amount of resources and with the threat of widespread infection in the health services.
Intergruppo Melanoma Italiano
doaj   +1 more source

Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]

open access: yes, 2008
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A.   +9 more
core   +1 more source

Association of MC1R Variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study [PDF]

open access: yes, 2010
<p><b>Background</b> Carrying the cyclin-dependent kinase inhibitor 2A (CDKN2A) germline mutations is associated with a high risk for melanoma. Penetrance of CDKN2A mutations is modified by pigmentation characteristics, nevus phenotypes,
Pastorino, L.   +283 more
core   +1 more source

PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells [PDF]

open access: yes, 2011
PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of ...
Ungerer Christopher   +49 more
core   +2 more sources

Melanoma

open access: yesClinical Radiology, 2004
The incidence of malignant melanoma in the UK is still rising despite public health warnings about the risks of excessive sun exposure. This aggressive tumour can metastasize to virtually any organ, even years after resection of the primary lesion and cause a variety of radiological appearances.
E, Kalkman, G, Baxter
openaire   +4 more sources

01 | End-of-life care in advanced melanoma and other skin cancers: a retrospective cohort from an italian comprehensive cancer center

open access: yesDermatology Reports
Background: Despite improvements in overall survival (OS) with immune-checkpoint inhibitors (ICIs) and targeted therapies, many patients with advanced melanoma or non-melanoma skin cancer (NMSC) still experience disease progression (PD) and remain on ...
Italian Melanoma Intergroup
doaj   +3 more sources

Cross-platform comparison of immune signatures in immunotherapy-treated patients with advanced melanoma using a rank-based scoring approach

open access: yesJournal of Translational Medicine, 2023
Background Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring approach has been developed to alleviate instability of signature scores due to ...
Yizhe Mao   +17 more
doaj   +1 more source

Home - About - Disclaimer - Privacy