Results 41 to 50 of about 593,039 (291)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Dermatology ReportsBackground: Cutaneous squamous cell carcinoma (cSCC) is the second most frequent non-melanoma skin cancer, with a 10-year survival rate >90% after surgical resection.
Italian Melanoma Intergroup
doaj +1 more source
Frontiers in Genetics, 2013 Genomic variation is a trend observed in various human diseases including cancer. Genetic studies have set out to understand how and why these variations result in cancer, why some populations are pre-disposed to the disease, and also how genetics affect drug responses. The melanoma incidence has been increasing at an alarming rate worldwide.
Wangari-Talbot, Janet, Chen, Suzie
openaire +3 more sources
Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression [PDF]
, 2011 P>Cell senescence is a permanent growth arrest following extended proliferation. Cultured cancer cells including metastatic melanoma cells often appear immortal (proliferate indefinitely), while uncultured benign nevi (moles) show senescence markers ...
Marais, R. +40 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Dermatology ReportsBackground: Stage IB–IIC melanoma with negative sentinel lymph node (SLN) status shows heterogeneous recurrence risk. Hematoxylin and eosin (H&E) slides capture tissue morphology, while immunohistochemistry (IHC) assays highlight immune, proliferative ...
Italian Melanoma Intergroup
doaj +1 more source
Journal of Translational Medicine, 2023 Background Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring approach has been developed to alleviate instability of signature scores due to ...
Yizhe Mao +17 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Dermatology ReportsBackground: Educational initiatives among young people are pivotal in promoting healthy behaviors, yet only a few studies to date have used peer education in schools to convey health messages for melanoma prevention.
Italian Melanoma Intergroup
doaj +1 more source
XXVI IMI National Congress - 1st virtual edition | 7-9 November 2020
Dermatology Reports, 2021 s from the XXVI IMI National Congress (virtual edition).
Italian Melanoma Intergroup (IMI)
doaj +1 more source