Results 61 to 70 of about 528,594 (306)
JCO Global Oncology, 2020 PURPOSE National epidemiologic data on melanoma are scarce in Brazil. The current work presents final demographic, clinical, and pathologic results from the Brazilian Melanoma Group database to detail how patients with melanoma present at diagnosis ...
Alberto Julius Alves Wainstein +20 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Frontiers in Genetics, 2013 Genomic variation is a trend observed in various human diseases including cancer. Genetic studies have set out to understand how and why these variations result in cancer, why some populations are pre-disposed to the disease, and also how genetics affect drug responses. The melanoma incidence has been increasing at an alarming rate worldwide.
Wangari-Talbot, Janet, Chen, Suzie
openaire +3 more sources
Dermatology ReportsBackground: The relationship between occupational sun exposure and melanoma risk is complex and multifactorial, with conflicting evidence in the literature.
Italian Melanoma Intergroup
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Measles virus causes immunogenic cell death in human melanoma
, 2011 NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Russell, S +44 more
core +1 more source
Dermatology ReportsBackground: Hedgehog Pathway Inhibitors (HHIs) should be offered to patients with advanced BCC as a first line treatment. Two systemic HHIs are currently available: sonidegib and vismodegib.
Italian Melanoma Intergroup
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Molecular genetics and mechanisms of pigmentation and melanoma [PDF]
, 2010 Ever since man domesticated the first wild animals several thousand years ago, many species have been living in close relationship with humans, being objects for our requests and wishes about any kind of phenotypic traits.
Sundström, Elisabeth
core
15 | Clinico-pathological features of superficial angiosarcomas: a retrospective study
Dermatology ReportsBackground: Angiosarcoma (AS) is a rare malignant vascular neoplasm, classified as either deep or superficial. Among superficial forms, cutaneous angiosarcoma (cAS) and radiation-induced angiosarcoma of the breast (RIAS) are the most frequent.
Italian Melanoma Intergroup
doaj +1 more source