Results 61 to 70 of about 530,239 (305)

22 | Surgical radicality and reconstructive techniques in melanoma and non-melanoma skin cancer

open access: yesDermatology Reports
Background: This prospective case series evaluated the clinical outcomes of skin micro-fragment therapy in managing the excision of local advanced skin cancer. Recently, skin micro-fragment therapy has emerged as a promising alternative of classical skin
Italian Melanoma Intergroup
doaj   +1 more source

Melanoma of the Foot [PDF]

open access: yesClinics in Podiatric Medicine and Surgery, 2016
Melanoma is a rare form of skin cancer that is responsible for most skin cancer deaths globally. Tumors arising on the foot continue to be a particular challenge. Patients present later and lesions are frequently misdiagnosed, leading to more advanced disease with an overall poorer prognosis then melanoma elsewhere.
Bristow, Ivan, Bower, Chris
openaire   +4 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

TP63 is implicated in apoptotic dysregulation in melanoma [PDF]

open access: yes, 2010
PhDCutaneous melanoma is an aggressive malignancy accounting for 4% of skin cancers but 80% of all skin-cancer related deaths. Its incidence is rapidly rising and advanced disease is notoriously treatment-resistant.
Matin, Rubeta N H
core  

18 | Surgical management of pregnancy-associated melanoma: a single institution experience with thirty-three pregnant patients

open access: yesDermatology Reports
Background: Pregnancy-associated melanoma (PAM) has been associated with poorer outcomes, although the prognostic role of pregnancy remains controversial. Management of PAM is challenging, as no established guidelines are available.
Italian Melanoma Intergroup
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

‘I am not someone who gets skin cancer’: Risk, time and malignant melanoma [PDF]

open access: yes, 2013
‘Delay’ is a term used in the cancer literature since the 1930s to describe the period between self-detection of a concerning sign of possible disease and presentation to a health professional.
Heyman, Bob   +5 more
core   +1 more source

Demographic, Clinical, and Pathologic Features of Patients With Cutaneous Melanoma: Final Analysis of the Brazilian Melanoma Group Database

open access: yesJCO Global Oncology, 2020
PURPOSE National epidemiologic data on melanoma are scarce in Brazil. The current work presents final demographic, clinical, and pathologic results from the Brazilian Melanoma Group database to detail how patients with melanoma present at diagnosis ...
Alberto Julius Alves Wainstein   +20 more
doaj   +1 more source

Genetics of melanoma [PDF]

open access: yesFrontiers in Genetics, 2013
Genomic variation is a trend observed in various human diseases including cancer. Genetic studies have set out to understand how and why these variations result in cancer, why some populations are pre-disposed to the disease, and also how genetics affect drug responses. The melanoma incidence has been increasing at an alarming rate worldwide.
Wangari-Talbot, Janet, Chen, Suzie
openaire   +3 more sources

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

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