Results 11 to 20 of about 528,594 (306)

Melanoma [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2012
Melanoma is a relatively common neoplasm which is increasing in incidence. Melanoma appears as a variegated irregular maculopapular lesion usually on the skin, but possibly on mucosae, conjunctiva, orbit, nails and oesophagus. They may be black, brown,
Daniel G, Coit   +24 more
openaire   +4 more sources

Melanoma [PDF]

open access: yesCanadian Medical Association Journal, 2019
AbstractCurrent recommendations by the United States Preventive Services Task Force do not support screening for skin cancer. Melanoma is unique among cancers because detection is through visual inspection. Development of technologies that aid visual inspection have supported screening strategies in high‐risk populations such as older fair skinned ...
Robert, Micieli, Kucy, Pon
openaire   +4 more sources

Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]

open access: yes, 2008
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A.   +9 more
core   +1 more source

New Advances in Melanoma [PDF]

open access: yes, 2022
Melanoma is a very aggressive tumor which is derived from the transformation of pigment-producing cells termed the melanocytes. This cancer type accounts for most of the deaths associated with skin cancer as well as its incidence and is in constant ...

core   +2 more sources

Association of MC1R Variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study [PDF]

open access: yes, 2010
<p><b>Background</b> Carrying the cyclin-dependent kinase inhibitor 2A (CDKN2A) germline mutations is associated with a high risk for melanoma. Penetrance of CDKN2A mutations is modified by pigmentation characteristics, nevus phenotypes,
Pastorino, L.   +274 more
core   +1 more source

PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells [PDF]

open access: yes, 2011
PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of ...
Ungerer Christopher   +49 more
core   +1 more source

Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. [PDF]

open access: yes, 2012
Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms.
Berking, Carola   +18 more
core   +1 more source

Development of a practical guide for the early recognition for malignant melanoma of the foot and nail unit [PDF]

open access: yes, 2010
Background: malignant melanoma is a rare but potentially lethal form of cancer which may arise on the foot. Evidence suggests that due to misdiagnosis and later recognition, foot melanoma has a poorer prognosis than cutaneous melanoma elsewhere.Methods ...
David AR de Berker   +5 more
core   +1 more source

Primary dermal melanoma in a patient with a history of multiple malignancies: a case report with molecular characterization [PDF]

open access: yes, 2013
Introduction: Primary dermal melanoma (PDM) is a recently described clinical entity accounting for less than 1% of all melanomas. Histologically, it is located in the dermis or subcutaneous tissue, and it shows no connections with the overlying epidermis.
Palomba, Grazia   +19 more
core   +1 more source

The Outcome of Patients with Melanoma Is Not Associated with the Time Point of Lymphatic Mapping with Respect to Excisional Biopsy of the Primary Tumor [PDF]

open access: yes, 2010
Background: Sentinel lymph node biopsy (SLNB) has become the standard care for melanoma and is an important diagnostic procedure. It has been doubted whether lymphoscintigraphy detects the correct sentinel lymph node (SLN) when excision of the tumor and ...
Ruzicka, T.   +15 more
core   +1 more source

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