Results 41 to 50 of about 230,496 (168)
Abscopal Effects of Local Radiotherapy Are Dependent on Tumor Immunogenicity
Frontiers in Oncology, 2021 Although abscopal tumor regression remains a rare phenomenon, interest in exploiting how radiation stimulates the immune system to induce systemic abscopal response is increasing.
Jin-Zhi Lai +7 more
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, 2020 Immunotherapy is now widely established as a potent and effective treatment option across several types of cancer. However, there is increasing recognition that not all patients respond to immunotherapy, focusing attention on the immune contexture of the
Spranger-Zimmermann, Stefani
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Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again
Genome Medicine, 2018 For at least 300 years the immune system has been targeted to improve human health. Decades of work advancing immunotherapies against infection and autoimmunity paved the way for the current explosion in cancer immunotherapies.
Samantha L. Bucktrout +2 more
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Metabolic Barriers to Glioblastoma Immunotherapy
, 2023 Glioblastoma (GBM) is the most common primary brain tumor with a poor prognosis with the current standard of care treatment. To address the need for novel therapeutic options in GBM, immunotherapies which target cancer cells through stimulating an anti ...
Jun Y. Oh +3 more
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Role of Exosomes in Immunotherapy of Hepatocellular Carcinoma
, 2022 SIMPLE SUMMARY: Hepatocellular carcinoma is one of the most lethal malignancies, having a significantly poor prognosis. Immunotherapy, as an emerging tumor treatment option, provides new hope for many cancer patients.
Tian, Bao-Wen +11 more
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CAR T cell cancer immunotherapy: who does the job?
Frontiers in ImmunologyChimeric antigen receptor (CAR) T cells are capable to eliminate cancer cells in the treatment of hematologic malignancies, yet the efficacy is frequently inconsistent and limited by cancer cell resistance and antigen-loss resulting in early tumor ...
Dennis Christoph Harrer +3 more
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ERAP1 overexpression in HPV-induced malignancies: A possible novel immune evasion mechanism
OncoImmunology, 2017 Immune evasion of tumors poses a major challenge for immunotherapy. For human papillomavirus (HPV)-induced malignancies, multiple immune evasion mechanisms have been described, including altered expression of antigen processing machinery (APM) components.
Alina Steinbach +9 more
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Clinical Applications of Immunotherapy for Recurrent Glioblastoma in Adults
, 2023 Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Despite standard therapies, including resection and chemoradiation, recurrence is virtually inevitable. Current treatment for recurrent glioblastoma (rGBM) is rapidly evolving,
Meagan Mandabach Olivet +6 more
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Communications BiologyExperimental autoimmune encephalomyelitis (EAE) is a demyelinating disease affecting the central nervous system (CNS) in animals that parallels several clinical and molecular traits of multiple sclerosis in humans.
Luisa F. Duarte +13 more
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Cancer Immunology, ImmunotherapyBackground Lymphocyte antigen 6 complex, locus E (Ly6E) has been initially demonstrated to involve in T cell activity and impair viral infectivity. Recently, high expression levels of Ly6E have been reported in tumor microenvironment (TME) of various ...
Lan Hailin +7 more
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