Results 41 to 50 of about 261,478 (313)
Hypoxia helps glioma to fight therapy [PDF]
, 2009 Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena +1 more
core +2 more sources
Cancer Cell International, 2019 Background The plant homeodomain (PHD) finger protein 14 (PHF14) is a vital member of PHD finger protein families. Abnormal expression of PHF14 has been identified in various cancers and is known to be implicated in the pathogenesis of tumors. This study
Shuai Wu +5 more
doaj +1 more source
, 2022 Among the malignant tumors in the central nervous system (CNS), glioma is the most challenging tumor to the public society, which accounts for the majority of intracranial malignant tumors with impaired brain function.
1000050242110 +12 more
core +1 more source
An online survival predictor in glioma patients using machine learning based on WHO CNS5 data
Frontiers in Neurology, 2023 BackgroundThe World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas.
Liguo Ye +30 more
doaj +1 more source
(Pro)renin receptor is crucial for glioma development via the Wnt/β-catenin signaling pathway [PDF]
, 2017 香川大学Kagawa University博士（医学）OBJECTIVE The (pro)renin receptor (PRR) plays an essential role in the early development of the central nervous system by activating the Wnt/β-catenin signaling pathway. The authors investigated the potential role of the PRR in
コウチ, マサアキ +2 more
core +1 more source
Glioma, 2022 Background and Aim: High-grade glioma is the most common malignant primary brain tumor in the central nervous system. Multiple strategies such as surgery, radiotherapy, and chemotherapy have been used, but the prognosis of patients with high-grade glioma
Fuhua Lin +15 more
doaj +1 more source
Medical Hypotheses, 2012 Glial neoplasms account for nearly 50% of all adult primary brain tumors. They originate from glial cells in the brain and/or spinal cord and include low-grade diffuse astrocytomas, anaplastic-astrocytomas, and glioblastomas. Of all brain tumors, glioblastoma multiforme (GBM) is the most aggressive and is characterized by rapid glial cell growth ...
O, Prakash +4 more
openaire +2 more sources
Monoclonal antibodies against human astrocytomas and their reactivity pattern [PDF]
, 1987 The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 × 106 chemically modified uncultured or cultured glioma cells.
Eisenmenger, Wolfgang +8 more
core +1 more source
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation [PDF]
, 2011 Background: We analyzed prospectively whether MGMT (O(6)-methylguanine-DNA methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT promoter methylation in malignant glioma patients undergoing radiotherapy with ...
Kreth Simone +35 more
core +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source