Results 41 to 50 of about 382,034 (365)
Electrical and synaptic integration of glioma into neural circuits
Nature, 2019 High-grade gliomas are lethal brain cancers whose progression is robustly regulated by neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but this alone is insufficient to explain the effect that neuronal activity ...
H. Venkatesh +20 more
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IDH mutation in glioma: molecular mechanisms and potential therapeutic targets
British Journal of Cancer, 2020 Isocitrate dehydrogenase (IDH) enzymes catalyse the oxidative decarboxylation of isocitrate and therefore play key roles in the Krebs cycle and cellular homoeostasis.
Sue Han +7 more
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Hypoxia helps glioma to fight therapy [PDF]
, 2009 Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena +1 more
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Scientific Reports, 2022 Glioblastoma has remained the deadliest primary brain tumor while its current therapy offers only modest survival prolongation. Immunotherapy has failed to record notable benefits in routine glioblastoma treatment. Conventionally, immunotherapy relies on
Jan Kopecky +5 more
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Immunotherapy for glioma: current management and future application.
Cancer Letters, 2020 Gliomas are intrinsic brain tumors that originate from neuroglial progenitor cells. Conventional therapies, including surgery, chemotherapy, and radiotherapy, have achieved limited improvements in the prognosis of glioma patients.
Shengchao Xu +4 more
semanticscholar +1 more source
bioRxiv, 2020 Gliomas are the most common and malignant intracranial tumours in adults. Recent studies have shown that functional genomics greatly aids in the understanding of the pathophysiology and therapy of glioma.
Zheng Zhao +12 more
semanticscholar +1 more source
, 2022 Among the malignant tumors in the central nervous system (CNS), glioma is the most challenging tumor to the public society, which accounts for the majority of intracranial malignant tumors with impaired brain function.
1000050242110 +12 more
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Cancer Cell International, 2019 Background The plant homeodomain (PHD) finger protein 14 (PHF14) is a vital member of PHD finger protein families. Abnormal expression of PHF14 has been identified in various cancers and is known to be implicated in the pathogenesis of tumors. This study
Shuai Wu +5 more
doaj +1 more source
An online survival predictor in glioma patients using machine learning based on WHO CNS5 data
Frontiers in Neurology, 2023 BackgroundThe World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas.
Liguo Ye +30 more
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(Pro)renin receptor is crucial for glioma development via the Wnt/β-catenin signaling pathway [PDF]
, 2017 香川大学Kagawa University博士（医学）OBJECTIVE The (pro)renin receptor (PRR) plays an essential role in the early development of the central nervous system by activating the Wnt/β-catenin signaling pathway. The authors investigated the potential role of the PRR in
コウチ, マサアキ +2 more
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