Results 31 to 40 of about 118,499 (334)

Lead and the mitochondrion [PDF]

Postgraduate Medical Journal, 1975
Summary In studies on the distribution of lead in rats given drinking water containing lead acetate at concentrations: 0, 100, 500, 1000 and 5000 μgPb/l for one year, no change was observed in the organ distribution of lead, or in the subcellular distribution of lead in the organelles in the heart. The mitochondrial enzyme,
openaire   +3 more sources

Common Structural Patterns in the Maxicircle Divergent Region of Trypanosomatidae

Pathogens, 2020
Maxicircles of all kinetoplastid flagellates are functional analogs of mitochondrial genome of other eukaryotes. They consist of two distinct parts, called the coding region and the divergent region (DR). The DR is composed of highly repetitive sequences
Evgeny S. Gerasimov, Ksenia A. Zamyatnina, Nadezda S. Matveeva, Yulia A. Rudenskaya, Natalya Kraeva, Alexander A. Kolesnikov, Vyacheslav Yurchenko   +6 more
doaj   +1 more source

Effects of Eccentric Exercise on Skeletal Muscle Injury: From An Ultrastructure Aspect: A Review

Physical Activity and Health, 2021
The contraction of skeletal muscle (SM) plays an important role in providing power for the body to participate in physical activities. Nevertheless, unaccustomed motions, especially eccentric exercises (EE), might cause changes in ultrastructure and ...
Jianhua Ying, Xuanzhen Cen, Peimin Yu
doaj   +1 more source

Analysis of two genomes from the mitochondrion-like organelle of the intestinal parasite Blastocystis: complete sequences, gene content, and genome organization. [PDF]

, 2008
Acquisition of mitochondria by the ancestor of all living eukaryotes represented a crucial milestone in the evolution of the eukaryotic cell. Nevertheless, a number of anaerobic unicellular eukaryotes have secondarily discarded certain mitochondrial ...
Clark, C Graham, Pérez-Brocal, Vicente
core   +2 more sources

Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels [PDF]

, 2001
Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these ...
Benne R., Beverley S.M., Brun R., Carruthers V.B., Czichos J., Feagin J.E., Folsch H., Hahne K., Hauser R., Hausler T., Hirumi H., Kwast K.E., LeBowitz J.H., Matthews K.R., Osinga K.A., Overath P., Priest J.W., Roditi I., Sherwin T., Smagula C., Sogin M.L., Stuart K., Tasker M., Torri A.F., Tschudi C., Ullu E., Vassella E., Wirtz E., Woods A., Ziegelbauer K.   +29 more
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Metformin ameliorates the mitochondrial damage induced by C9ORF72 amyotrophic lateral sclerosis/frontotemporal dementia-related poly-GR

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To investigate the effect of C9ORF72 amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD)-related poly-glycine-arginine (poly-GR) on mitochondrial morphology and function, and analyze the rescue effect of metformin on mitochondrial ...
FENG Yiyuan, XU Zhongyun, YIN Yafu, WANG Hui, CHENG Weiwei   +4 more
doaj   +1 more source

What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research [PDF]

, 2015
Mitochondria can change their shape from discrete isolated organelles to a large continuous reticulum. The cellular advantages underlying these fused networks are still incompletely understood.
Ainscow, Amchenkova, Bakeeva, Bazil, Beard, Bernardi, Brand, Braschi, Busch, Cagalinec, Castanier, Chan, Chen, Chen, Chen, Chouhan, Cipolat, Cortassa, das Neves, De Marchi, Dedkova, Denton, Denton, Ehses, Estaquier, Figge, Fischer, Frezza, Friedman, Gilkerson, Gilkerson, Gomes, Gottlieb, Grandemange, Groen, Harrison, Head, Hemion, Imai, Jahani-Asl, Jahani-Asl, Jimenez, Johnston, Johnston, Junesch, Kim, Kowald, Krapivsky, Laar, Lee, Legros, Lemasters, Liesa, Liu, Liu, Logan, Magnus, Mai, Malli, Maltecca, McBride, McCormack, Meeusen, Mishra, Mitra, Mitra, Mouli, Murphy, Nakada, Narendra, Neuspiel, Olichon, Ong, Ono, Parone, Partikian, Patel, Patergnani, Patten, Picard, Picard, Qian, Rafelski, Rafelski, Rambold, Rizzuto, Rizzuto, Rodell, Rolland, Saa, Sahimi, Skulachev, Skulachev, Soboll, Soga, Song, Soubannier, Stauffer, Sukhorukov, Szabadkai, Tondera, Twig, Twig, van der Bliek, Verkman, Vinnakota, Viola, Wan, Westrate, Wikstrom, Wikstrom, Wilkens, Wu, Wu, Youle, Zemirli, Zhang, Zhu   +117 more
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Cell Biology of the Mitochondrion [PDF]

Genetics, 2017
AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M, Sedensky, Margaret M, Morgan, Phil G   +2 more
openaire   +5 more sources

Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]

, 2018
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin, Johnson, Carla, Mallo, Natalia, Sheiner, Lilach   +3 more
core   +1 more source

Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice

Frontiers in Aging Neuroscience, 2017
D-galactose has been reported to accelerate senescence in rodents, accompanied by a decline in learning and memory. We used a model of D-galactose-induced amnesia for the efficacy evaluation and pharmacologic studies of active compounds against Alzheimer’
Wenwen Lian, Hao Jia, Lvjie Xu, Wei Zhou, De Kang, Ailin Liu, Guanhua Du   +6 more
doaj   +1 more source