Motile cilia are hair-like organelles that protrude from the cell surface and are conserved throughout eukaryotes. Motile cilia beat rhythmically and function in cellular and organismal locomotion and in driving fluid transport over epithelia.
Roy, Sudipto, Zhou, Feng
core +4 more sources
Motile cilia and airway disease. [PDF]
A finely regulated system of airway epithelial development governs the differentiation of motile ciliated cells of the human respiratory tract, conferring the body's mucociliary clearance defence system. Human cilia dysfunction can arise through genetic mutations and this is a cause of debilitating disease morbidities that confer a greatly reduced ...
M. Legendre, L. Zaragosi, H. Mitchison
semanticscholar +6 more sources
Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport. [PDF]
Significance The oviduct is essential for female fertility due to its two main functions: transport and nourishment. While the nourishment role is mainly fulfilled by secretory cells, the relative contribution to the transport function by ciliated cells ...
Yuan S+6 more
europepmc +2 more sources
Impact of Motile Ciliopathies on Human Development and Clinical Consequences in the Newborn [PDF]
Motile cilia are hairlike organelles that project outward from a tissue-restricted subset of cells to direct fluid flow. During human development motile cilia guide determination of the left-right axis in the embryo, and in the fetal and neonatal periods
Rachael M. Hyland, Steven L. Brody
doaj +3 more sources
Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia. [PDF]
Idiopathic normal pressure hydrocephalus (iNPH) is considered an age-dependent chronic communicating hydrocephalus associated with cerebrospinal fluid (CSF) malabsorption; however, the aetiology of ventricular enlargement in iNPH has not yet been ...
Yamada S, Ishikawa M, Nozaki K.
europepmc +2 more sources
Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating. [PDF]
Motile cilia of multiciliated epithelial cells undergo synchronized beating to produce fluid flow along the luminal surface of various organs. Each motile cilium consists of an axoneme and a basal body (BB), which are linked by a “transition zone” (TZ ...
Saito H+15 more
europepmc +2 more sources
Cyclic GMP and Cilia Motility [PDF]
Motile cilia of the lungs respond to environmental challenges by increasing their ciliary beat frequency in order to enhance mucociliary clearance as a fundamental tenant of innate defense.
Todd A. Wyatt
doaj +4 more sources
ARL13B controls male reproductive tract physiology through primary and Motile Cilia [PDF]
ARL13B is a small regulatory GTPase that controls ciliary membrane composition in both motile cilia and non-motile primary cilia. In this study, we investigated the role of ARL13B in the efferent ductules, tubules of the male reproductive tract essential
Céline Augière+13 more
doaj +2 more sources
Motile Cilia in Female and Male Reproductive Tracts and Fertility [PDF]
Motile cilia are evolutionarily conserved organelles. In humans, multiciliated cells (MCCs), assembling several hundred motile cilia on their apical surface, are components of the monolayer epithelia lining lower and upper airways, brain ventricles, and ...
Dorota Wloga+4 more
doaj +2 more sources
Emergence of Collective Dynamics in Systems of Motile Cilia [PDF]
Motile cilia are fascinating structures, evolved very early in eukaryotes, and highly conserved throughout organisms of very different complexity. They generate the transport of fluid by periodic beating, through remarkably organized behaviour in space and time (e.g. collective waves).
Pietro Cicuta+7 more
openalex +3 more sources