Results 1 to 10 of about 78,565 (291)

Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle

Cell & Bioscience
Cilia are versatile, microtubule-based organelles that facilitate cellular signaling, motility, and environmental sensing in eukaryotic cells. These dynamic structures act as hubs for key developmental signaling pathways, while their assembly and ...
Lukáš Čajánek, Sindija Smite, Olha Ivashchenko, Martina Huranova   +3 more
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Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

Frontiers in Cell and Developmental Biology, 2021
Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the plasma membrane comprises an axoneme composed of microtubule doublets, arranged in a 9 + 0 ...
Paweł K. Łysyganicz, Paweł K. Łysyganicz, Niedharsan Pooranachandran, Xinming Liu, Kathryn I. Adamson, Kathryn I. Adamson, Katarzyna Zielonka, Katarzyna Zielonka, Stone Elworthy, Stone Elworthy, Fredericus J. van Eeden, Fredericus J. van Eeden, Andrew J. Grierson, Andrew J. Grierson, Jarema J. Malicki, Jarema J. Malicki   +15 more
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Motile Cilia in Female and Male Reproductive Tracts and Fertility

Cells
Motile cilia are evolutionarily conserved organelles. In humans, multiciliated cells (MCCs), assembling several hundred motile cilia on their apical surface, are components of the monolayer epithelia lining lower and upper airways, brain ventricles, and ...
Dorota Wloga, Ewa Joachimiak, Anna Osinka, Salman Ahmadi, Sumita Majhi   +4 more
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Genetic Ablation of Type III Adenylyl Cyclase Exerts Region-Specific Effects on Cilia Architecture in the Mouse Nose.

PLoS ONE, 2016
We recently reported that olfactory sensory neurons in the dorsal zone of the mouse olfactory epithelium exhibit drastic location-dependent differences in cilia length.
Rosemary C Challis, Huikai Tian, Wenbin Yin, Minghong Ma   +3 more
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A transgenic zebrafish for in vivo visualization of cilia

Open Biology, 2022
Cilia are organelles for cellular signalling and motility. Mutations affecting ciliary function are also associated with cilia-related disorders (ciliopathies).
Hongyu Zhang, Zhuoya Huang, Liuliu LV, Yuye Xin, Qian Wang, Feng Li, Lina Dong, Changxin Wu, Philip W. Ingham, Zhonghua Zhao   +9 more
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Ectopic Cilia:A Histopathological Study

Case Reports in Dermatology, 2012
Cilia are normally found at the eyelid margin, while ectopic cilia are one or more lash follicles appearing in an abnormal position within the eyelid. We herein report two cases of cilia located in the palpebral conjunctiva. A 31-year-old female and a 46-
Keitaro Hase, Satoru Kase, Mika Noda, Tsutomu Ohashi, Satoru Shinkuma, Susumu Ishida   +5 more
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Fluorescence imaging of beta cell primary cilia

Frontiers in Endocrinology, 2022
Primary cilia are slender cell-surface organelles that project into the intercellular space. In pancreatic beta cells, primary cilia coordinate a variety of cell responses including GPCR signaling, calcium influx, and insulin secretion, along with likely
Zipeng A. Li, Jung Hoon Cho, Louis G. Woodhams, Jing W. Hughes   +3 more
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A Simple Method for Imaging and Quantifying Respiratory Cilia Motility in Mouse Models

Methods and Protocols
A straightforward ex vivo approach has been developed and refined to enable high-resolution imaging and quantitative assessment of motile cilia function in mouse airway epithelial tissue, allowing critical insights into cilia motility and cilia generated
Richard Francis
doaj   +1 more source

Ion channels and calcium signaling in motile cilia

eLife, 2015
The beating of motile cilia generates fluid flow over epithelia in brain ventricles, airways, and Fallopian tubes. Here, we patch clamp single motile cilia of mammalian ependymal cells and examine their potential function as a calcium signaling ...
Julia F Doerner, Markus Delling, David E Clapham   +2 more
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Heterogeneity of radial spoke components in Tetrahymena cilia

Cellular and Molecular Life Sciences
Radial spokes, RS1, RS2, and RS3, are T-shaped, multiprotein complexes that transmit regulatory signals from the central apparatus to outer doublet complexes, including dynein arms.
Marta Bicka, Avrin Ghanaeian, Corbin Black, Ewa Joachimiak, Anna Osinka, Sumita Majhi, Anna Konopka, Ewa Bulska, Khanh Huy Bui, Dorota Wloga   +9 more
doaj   +1 more source