Results 31 to 40 of about 71,498 (314)
Smoking is associated with shortened airway cilia. [PDF]
PLoS ONE, 2009 BACKGROUND:Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length.
Philip L Leopold +5 more
doaj +1 more source
Cells, 2022 Cilia are hair-like projections of the plasma membrane with an inner microtubule skeleton known as axoneme. Motile cilia and flagella beat to displace extracellular fluids, playing important roles in the airways and reproductive system.
Pablo López-Jiménez +5 more
doaj +1 more source
Philosophical Transactions of the Royal Society B: Biological Sciences, 2019 Cilia, or eukaryotic flagella, are microscopic active filaments expressed on the surface of many eukaryotic cells, from single-celled protozoa to mammalian epithelial surfaces. Cilia are characterized by a highly conserved and intricate internal structure in which molecular motors exert forces on microtubule doublets causing cilia oscillations.
Yi Man, Feng Ling, Eva Kanso
openaire +3 more sources
Cilia Action in Islets: Lessons From Mouse Models
Frontiers in Endocrinology, 2022 Primary cilia as a signaling organelle have garnered recent attention as a regulator of pancreatic islet function. These rod-like sensors exist on all major islet endocrine cell types and transduce a variety of external cues, while dysregulation of cilia
Jung Hoon Cho, Jing W. Hughes
doaj +1 more source
Pix proteins and the evolution of centrioles [PDF]
, 2008 We have made a wide phylogenetic survey of Pix proteins, which are constituents of vertebrate centrioles in most eukaryotes. We have also surveyed the presence and structure of flagella or cilia and centrioles in these organisms, as far as is possible ...
Fry, Andrew M. +7 more
core +1 more source
PLoS Genetics, 2020 Motile cilia can beat with distinct patterns, but how motility variations are regulated remain obscure. Here, we have studied the role of the coiled-coil protein CFAP53 in the motility of different cilia-types in the mouse.
Takahiro Ide +12 more
doaj +1 more source
Coordination of Cilia Movements in Multi-Ciliated Cells
Journal of Developmental Biology, 2022 Multiple motile cilia are formed at the apical surface of multi-ciliated cells in the epithelium of the oviduct or the fallopian tube, the trachea, and the ventricle of the brain. Those cilia beat unidirectionally along the tissue axis, and this provides
Masaki Arata +2 more
doaj +1 more source
IFT46 Expression in the Nasal Mucosa of Primary Ciliary Dyskinesia Patients: Preliminary Study
Allergy & Rhinology, 2021 Background Primary ciliary dyskinesia (PCD) is characterised by an imbalance in mucociliary clearance leading to chronic respiratory infections. Cilia length is considered to be a contributing factor in cilia movement.
Manuel Mata PhD +6 more
doaj +1 more source
Neuronal cilia in energy homeostasis
Frontiers in Cell and Developmental Biology, 2022 A subset of genetic disorders termed ciliopathies are associated with obesity. The mechanisms behind cilia dysfunction and altered energy homeostasis in these syndromes are complex and likely involve deficits in both development and adult homeostasis ...
Kathryn M. Brewer +5 more
doaj +1 more source
Current Osteoporosis Reports, 2023 Abstract Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing. Recent Findings Osteocytes are thought to be the primary mechanosensing cells in bone tissue ...
Verbruggen, S.W. +2 more
openaire +4 more sources