Results 31 to 40 of about 78,565 (291)
Tethered fleximags as artificial cilia [PDF]
, 2011 Flexible superparamagnetic filaments ('fleximags') are very slender elastic filaments, which can be driven by distributed magnetic torques to mimic closely the behaviour of biological flagella.
OLIVIA DU ROURE +7 more
core +1 more source
Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells
Molecules, 2020 Microtubules (MTs), highly dynamic structures composed of α- and β-tubulin heterodimers, are involved in cell movement and intracellular traffic and are essential for cell division.
Filip Borys +3 more
doaj +1 more source
Airway ciliated cells in adult lung homeostasis and COPD
European Respiratory Review, 2023 Cilia are organelles emanating from the cell surface, consisting of an axoneme of microtubules that extends from a basal body derived from the centrioles. They are either isolated and nonmotile (primary cilia), or grouped and motile (motile cilia). Cilia
Laure M.G. Petit +10 more
doaj +1 more source
Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation. [PDF]
, 2012 Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet-Biedl syndrome proteins form a complex that is important for several cytoskeleton-related processes such as ciliogenesis, cell migration and ...
D Jenkins +20 more
core +1 more source
Cells, 2019 Cilia are highly evolutionarily conserved, microtubule-based cell protrusions present in eukaryotic organisms from protists to humans, with the exception of fungi and higher plants.
Anna Osinka +5 more
doaj +1 more source
IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning
Nature Communications, 2017 Cytokinesis relies on central spindle organization and provides a spatial landmark for lumen formation. Here, the authors show that intraflagellar transport proteins are required for the localization of the cytokinetic regulator Aurora B and subsequent ...
Nicolas Taulet +8 more
doaj +1 more source
ARL13B regulates Sonic hedgehog signaling from outside primary cilia
eLife, 2020 ARL13B is a regulatory GTPase highly enriched in cilia. Complete loss of Arl13b disrupts cilia architecture, protein trafficking and Sonic hedgehog signaling. To determine whether ARL13B is required within cilia, we knocked in a cilia-excluded variant of
Eduardo D Gigante +4 more
doaj +1 more source
The Importance of Zebrafish in Biomedical Research
Acta Médica Portuguesa, 2013 Introduction: Zebrafish (Danio rerio) is an ideal model organism for the study of vertebrate development. This is due to the large clutches that each couple produces, with up to 200 embryos every 7 days, and to the fact that the embryos and larvae are ...
Bárbara Tavares, Susana Santos Lopes
doaj +1 more source
Philosophical Transactions of the Royal Society B: Biological Sciences, 2019 Cilia, or eukaryotic flagella, are microscopic active filaments expressed on the surface of many eukaryotic cells, from single-celled protozoa to mammalian epithelial surfaces. Cilia are characterized by a highly conserved and intricate internal structure in which molecular motors exert forces on microtubule doublets causing cilia oscillations.
Yi Man, Feng Ling, Eva Kanso
openaire +3 more sources
Identification and characterization of a novel allele of Caenorhabditis elegans bbs-7. [PDF]
PLoS ONE, 2014 Primary cilia play a role in the sensation of and response to the surrounding environment. Caenorhabditis elegans (C. elegans) have primary cilia only on the distal tips of some dendrites.
Kara Braunreiter +2 more
doaj +1 more source