Results 51 to 60 of about 71,498 (314)

Cilia in Brain Development and Disease

open access: yes, 2018
The development of the vertebrate brain follows a tightly coordinated course of partially concomitant events. Progressive regionalization of larger brain areas into defined progenitor fields depends on the locally restricted action of specific gene sets ...
Peter Swoboda   +5 more
core   +1 more source

Maintaining centrosomes and cilia [PDF]

open access: yes, 2017
The deposited item is a review and has been submitted to peer review. This publication hasn't any creative commons license associated.
Bettencourt-Dias, Mónica   +5 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Basal body stability and ciliogenesis requires the conserved component Poc1 [PDF]

open access: yes, 2009
Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly mechanism that first synthesizes the ninefold symmetrical cartwheel and subsequently leads to a stable cylindrical microtubule ...
Thomas H. Giddings   +9 more
core   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen   +7 more
wiley   +1 more source

Motile Cilia in Female and Male Reproductive Tracts and Fertility

open access: yesCells
Motile cilia are evolutionarily conserved organelles. In humans, multiciliated cells (MCCs), assembling several hundred motile cilia on their apical surface, are components of the monolayer epithelia lining lower and upper airways, brain ventricles, and ...
Dorota Wloga   +4 more
doaj   +1 more source

Fluorescence imaging of beta cell primary cilia

open access: yesFrontiers in Endocrinology, 2022
Primary cilia are slender cell-surface organelles that project into the intercellular space. In pancreatic beta cells, primary cilia coordinate a variety of cell responses including GPCR signaling, calcium influx, and insulin secretion, along with likely
Zipeng A. Li   +3 more
doaj   +1 more source

Particle Transport by Cilia Arrays in Parallel-Wall Channels

open access: yes, 2023
Cilia are thin hair-like organelles projecting from a cell body, which are found in many unicellular and multicellular organisms. Individual cilia in ciliary arrays often coordinate their motion, leading to formation of metachronal waves that can propel ...
Harun, Asma
core  

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

Flexible Dielectric Acoustic Resonator Patch for Tissue Regeneration

open access: yesAdvanced Materials, EarlyView.
A flexible dielectric acoustic resonator patch enables MHz‐range ultrasound generation through resonance amplification without using piezoelectric materials. Conformal integration on a curved substrate allows efficient acoustic delivery to tissue‐mimicking environments.
Donyoung Kang   +7 more
wiley   +1 more source

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