Results 31 to 40 of about 2,374,258 (245)

Pathogenesis of rhinitis

open access: yesClinical & Experimental Allergy, 2016
SummaryRhinitis is a heterogeneous condition that has been associated with inflammatory responses as in allergic rhinitis but can also occur in the absence of inflammation such as in so‐called idiopathic (previously ‘vasomotor’) rhinitis. Allergic rhinitis affects approximately one in four of the population of westernized countries and is characterized
A. O. Eifan, S. R. Durham
openaire   +4 more sources

Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]

open access: yes, 2017
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham   +105 more
core   +2 more sources

Epigenetic Regulation of Antifungal Drug Resistance

open access: yesJournal of Fungi, 2022
In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra   +3 more
doaj   +1 more source

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

open access: yesMicroorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto   +3 more
doaj   +1 more source

Roadblocks to translational challenges on viral pathogenesis. [PDF]

open access: yes, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven   +4 more
core   +1 more source

A case report of multiple primary prostate tumors with differential drug sensitivity

open access: yesNature Communications, 2020
Prostate cancer is often a multifocal disease but how best to manage this clinically remains unclear. Here, the authors report a single case study of a patient with two genetically diverse tumours which showed differential response to therapy.
Scott Wilkinson   +20 more
doaj   +1 more source

Comparative Genomic Analysis of Antimicrobial-Resistant Escherichia coli from South American Camelids in Central Germany

open access: yesMicroorganisms, 2022
South American camelids (SAC) are increasingly kept in Europe in close contact with humans and other livestock species and can potentially contribute to transmission chains of epizootic, zoonotic and antimicrobial-resistant (AMR) agents from and to ...
Belén González-Santamarina   +3 more
doaj   +1 more source

Intrahepatic cholangiocarcinoma: review and update [PDF]

open access: yes, 2018
Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies that could develop at any level from the biliary tree. CCA is currently classified into intrahepatic (iCCA), perihilar and distal on the basis of its anatomical location.
Alvaro, Domenico   +7 more
core   +1 more source

De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions

open access: yesJournal of Biological Engineering, 2019
Background The promise of biopharmaceuticals comprising one or more binding domains motivates the development of novel methods for de novo isolation and affinity maturation of virion-binding domains.
Pete Heinzelman   +4 more
doaj   +1 more source

The Pathogenesis of Vitiligo

open access: yesJournal of Cutaneous Medicine and Surgery, 2011
Background: Vitiligo is a commonly encountered pigmentary disorder. Numerous studies and investigations from all over the world have attempted to determine the mechanisms behind this disease; however, the pathogenesis of vitiligo remains elusive. Objective: In this comprehensive review article, we present the findings behind the five overarching ...
Marlene Dytoc, Neel Malhotra
openaire   +5 more sources

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