Results 31 to 40 of about 68,845 (338)

Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial. [PDF]

open access: yes, 2006
OBJECTIVES: We evaluated the hypothesis that cyclooxygenase (COX) inhibitor use might have counteracted a beneficial effect of postmenopausal hormone therapy, and account for the absence of cardioprotection in the Women's Health Initiative hormone trials.
Choe, John H   +11 more
core   +3 more sources

Outcomes of a GnRH Agonist Trigger Following a GnRH Antagonist or Flexible Progestin-Primed Ovarian Stimulation Cycle

open access: yesFrontiers in Endocrinology, 2022
A suggested explanation for the pituitary-suppressive effects of progestin-primed ovarian stimulation cycles (PPOS) is pituitary luteinizing hormone (LH) depletion with progestin exposure during the follicular phase.
Erkan Kalafat   +7 more
doaj   +1 more source

The present status of metformin in fertility-preserving treatment in atypical endometrial hyperplasia and endometrioid endometrial cancer

open access: yesFrontiers in Endocrinology, 2022
Progestin therapy is the main fertility-sparing treatment for women with endometrial cancer (EC) and atypical endometrial hyperplasia (AEH). However, still 15-25% of these women failed to achieve complete response (CR) and then lost their fertility after
Jun Guan   +3 more
doaj   +1 more source

Progestins and cancer

open access: yesGynecological Endocrinology, 1999
The role of progestins in breast tissue is less well defined than in the endometrium. Although in vitro studies have shown that progestins induce a similar decrease in both estrogen and progesterone receptors and an increase in 17beta-estradiol dehydrogenase in the breast as in the endometrium, epidemiologic studies have suggested that progestins ...
G. Plu-Bureau, R. Sitruk-Ware
openaire   +2 more sources

Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring

open access: yesFrontiers in Endocrinology, 2022
Epidemiological studies have shown that maternal hormone exposure is associated with autism spectrum disorders (ASD). The hormone oxytocin (OXT) is a central nervous neuropeptide that plays an important role in social behaviors as well as ASD etiology ...
Saijun Huang   +6 more
doaj   +1 more source

Assessing the risk of venous thromboembolic events in women taking progestin-only contraception: a meta-analysis [PDF]

open access: yes, 2013
Objectives: To evaluate the risk of venous thromboembolic events associated with the use of progestin-only contraception and whether that risk differs with the mode of drug delivery (oral, intrauterine, or depot injection).
Bauer, Kenneth Alan   +5 more
core   +1 more source

Effects of Progestin on Modulation of the Expression of Biomarkers in Endometriosis

open access: yesBiomedicines, 2023
Background: Our study aimed to examine the osteopontin (OPN) serum levels and tissue expression of CD44 and OPN in endometriosis-affected women both undergoing and not undergoing progestin treatment, and also to determine their involvement in the ...
Daniela Roxana Matasariu   +9 more
doaj   +1 more source

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

open access: yes, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna   +8 more
core   +1 more source

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]

open access: yes, 2009
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia   +9 more
core   +1 more source

Progestin vs. Gonadotropin-Releasing Hormone Antagonist for the Prevention of Premature Luteinizing Hormone Surges in Poor Responders Undergoing in vitro Fertilization Treatment: A Randomized Controlled Trial

open access: yesFrontiers in Endocrinology, 2019
Objective: Progestin was recently used as an alternative of gonadotropin-releasing hormone (GnRH) analog for preventing premature luteinizing hormone (LH) surge with the aid of vitrification techniques, however, limited data were available about the ...
Qiuju Chen   +8 more
semanticscholar   +1 more source

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