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Progestins - a review of clinical application in gynecology [PDF]
Aims Progestins are a group of substances with a wide range of applications. They are classified into pregnanes, estranes, and gonanes, and further divided into four generations based on their testosterone (TE) or progesterone (P4) origin.
Dominika Żyła +5 more
doaj +2 more sources
Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation
Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epithelium is poorly understood because we lack adequate ...
Marie Shamseddin +2 more
exaly +2 more sources
Fecal Progestin Extraction and Analysis for Non-invasive Monitoring of Ovarian Cycle in Beef Cows [PDF]
The aims of the present study were to determine presence of immunoreactive progestins in feces, correlate fecal progestins with plasma progesterone (P4) concentrations and subsequently assess the role of fecal progestins in monitoring estrous cycle in ...
N. Yimer§, Y. Rosnina*, H. Wahid, M.M. Bukar, A. Malik, K.C. Yap, M. Fahmi, P. Ganesamurthi and A.A. Saharee
doaj +5 more sources
Progestins as Anticancer Drugs and Chemosensitizers, New Targets and Applications
Progesterone and its synthetic analogues, progestins, participate in the regulation of cell differentiation, proliferation and cell cycle progression.
Tatiana A Fedotcheva
exaly +3 more sources
Estrogens, Progestins, and Headache
Approaches to the therapy of hormone-related headaches are reviewed from the Department of Neurology, Temple University School of Medicine and the Comprehensive Headache Center at Germantown Hospital, Philadelphia, PA, and the Reproductive Endocrine Unit,
J Gordon Millichap
doaj +3 more sources
The residues of progestins in milk are significant risk factors for teenage acne and may cause hormone-dependent cancers in consumers, so the determination of these residues in milk is very important.
Yan Su +4 more
doaj +1 more source
Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P4), are used globally in menopausal hormone therapy. Although the older progestins medroxyprogesterone acetate (MPA) and norethisterone (NET) have been implicated in
Meghan S. Perkins +4 more
doaj +1 more source
Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids. [PDF]
Progestins used in contraception and hormone replacement therapy are synthetic compounds designed to mimic the actions of the natural hormone progesterone and are classed into four consecutive generations.
Renate Louw-du Toit +4 more
doaj +1 more source
A comparative analysis of the cytostatic effects of progestins (gestobutanoyl, megestrol acetate, amol, dienogest, and medroxyprogesterone acetate), glucocorticoids (hydrocortisone, dexamethasone), and diclofenac on tumor cells was carried out in order ...
Darya Ulchenko +4 more
doaj +1 more source
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
core +2 more sources

