Results 1 to 10 of about 10,432 (237)
Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation
EMBO Molecular Medicine, 2021 Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epithelium is poorly understood because we lack adequate ...
Marie Shamseddin +2 more
exaly +2 more sources
Progestins - a review of clinical application in gynecology [PDF]
Annals of MedicineAims Progestins are a group of substances with a wide range of applications. They are classified into pregnanes, estranes, and gonanes, and further divided into four generations based on their testosterone (TE) or progesterone (P4) origin.
Dominika Żyła +5 more
doaj +2 more sources
Progestins as Anticancer Drugs and Chemosensitizers, New Targets and Applications
Pharmaceutics, 2021 Progesterone and its synthetic analogues, progestins, participate in the regulation of cell differentiation, proliferation and cell cycle progression.
Tatiana A Fedotcheva +1 more
exaly +3 more sources
Gynecological Endocrinology, 1999 The role of progestins in breast tissue is less well defined than in the endometrium. Although in vitro studies have shown that progestins induce a similar decrease in both estrogen and progesterone receptors and an increase in 17beta-estradiol dehydrogenase in the breast as in the endometrium, epidemiologic studies have suggested that progestins ...
R Sitruk-Ware
exaly +3 more sources
Estrogens, Progestins, and Headache
Pediatric Neurology Briefs, 1991 Approaches to the therapy of hormone-related headaches are reviewed from the Department of Neurology, Temple University School of Medicine and the Comprehensive Headache Center at Germantown Hospital, Philadelphia, PA, and the Reproductive Endocrine Unit,
J Gordon Millichap
doaj +3 more sources
Foods, 2023 The residues of progestins in milk are significant risk factors for teenage acne and may cause hormone-dependent cancers in consumers, so the determination of these residues in milk is very important.
Yan Su +4 more
doaj +1 more source
Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids. [PDF]
PLoS ONE, 2016 Progestins used in contraception and hormone replacement therapy are synthetic compounds designed to mimic the actions of the natural hormone progesterone and are classed into four consecutive generations.
Renate Louw-du Toit +4 more
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Frontiers in Endocrinology, 2022 Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P4), are used globally in menopausal hormone therapy. Although the older progestins medroxyprogesterone acetate (MPA) and norethisterone (NET) have been implicated in
Meghan S. Perkins +4 more
doaj +1 more source
Pharmaceutics, 2023 A comparative analysis of the cytostatic effects of progestins (gestobutanoyl, megestrol acetate, amol, dienogest, and medroxyprogesterone acetate), glucocorticoids (hydrocortisone, dexamethasone), and diclofenac on tumor cells was carried out in order ...
Darya Ulchenko +4 more
doaj +1 more source
Effects of oral contraceptives on metabolic parameters in adult premenopausal women: a meta-analysis
Endocrine Connections, 2020 Objective: To estimate the effect of oral contraceptives (OC) containing di fferent progestins on parameters of lipid and carbohydrate metabolism through a systematic review and meta-analysis. Patients and methods: Premenopausal women aged 18 or older,
Lina S Silva-Bermudez +6 more
doaj +1 more source