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Progesterone Resistance in Endometriosis: Current Evidence and Putative Mechanisms
International Journal of Molecular Sciences, 2023 Endometriosis is an estrogen-dependent disease characterized by the growth of endometrial-like tissue outside the uterus. Progestins are currently the most commonly used treatment for endometriosis because of their excellent therapeutic effects and ...
Ping Zhang, Guoyun Wang, Wang Guoyun
exaly +2 more sources
Progesterone in the Brain: Hormone, Neurosteroid and Neuroprotectant
International Journal of Molecular Sciences, 2020 Progesterone has a broad spectrum of actions in the brain. Among these, the neuroprotective effects are well documented. Progesterone neural effects are mediated by multiple signaling pathways involving binding to specific receptors (intracellular ...
Rachida Guennoun
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Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
International Journal of Molecular Sciences, 2019 In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window of receptivity.
Ryan M Marquardt, , Jung-Ho Shin
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Frontiers in Neuroendocrinology, 2020 Estradiol is the "prototypic" sex hormone of women. Yet, women have another sex hormone, which is often disregarded: Progesterone. The goal of this article is to provide a comprehensive review on progesterone, and its metabolite allopregnanolone ...
Inger Sundstrom-Poromaa +2 more
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Non-genomic mechanisms of progesterone action in the brain
Frontiers in Neuroscience, 2013 Progesterone is a gonadal steroid hormone whose physiological effects extend well beyond the strict confines of reproductive function. In fact, progesterone can have important effects on a variety of tissues, including the bone, the heart and the brain ...
Meharvan Singh +2 more
exaly +3 more sources
Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females. [PDF]
PLoS Pathogens, 2016 Over 100 million women use progesterone therapies worldwide. Despite having immunomodulatory and repair properties, their effects on the outcome of viral diseases outside of the reproductive tract have not been evaluated.
Olivia J Hall +7 more
doaj +2 more sources
Elevated Progesterone Levels on the Day of Oocyte Maturation May Affect Top Quality Embryo IVF Cycles. [PDF]
PLoS ONE, 2016 In contrast to the impact of elevated progesterone on endometrial receptivity, the data on whether increased progesterone levels affects the quality of embryos is still limited. This study retrospectively enrolled 4,236 fresh in vitro fertilization (IVF)
Bo Huang +7 more
doaj +2 more sources
Progesterone Receptor Regulation of Uterine Adaptation for Pregnancy
Trends in Endocrinology and Metabolism, 2018 Progesterone acts through the progesterone receptor to direct physiological adaption of the uterus in preparation of and carrying out pregnancy. Genome-wide transcriptome and cistrome analyses have uncovered new members and novel modifiers of the ...
San-Pin Wu, Francesco J Demayo
exaly +2 more sources
Vaginal versus Intramuscular Progesterone in the Prevention of Recurrent Preterm Labour [PDF]
Al-Azhar International Medical Journal, 2021 Background: Preterm labHarbor is characterized as the occurrence of uterine contractions of sufficient frequency and intensity to affect the cervix's progressive effacement and dilation before to term gestation.
Mahmoud Harb +2 more
doaj +1 more source
Progesterone Actions and Resistance in Gynecological Disorders
Cells, 2022 Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen and progesterone disrupts their complex regulatory mechanisms, leading to
J. MacLean, Kanako Hayashi
semanticscholar +1 more source