Results 11 to 20 of about 281,417 (260)
Progesterone receptors in the human placenta: Expression, signalling characteristics and functional relevance [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The human placenta is a transient life sustaining organ which is responsible for mediating all the physiological exchanges between the mother and the fetus.
Zachariades, Elena
core +7 more sources
A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]
The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Christopher M. Fanger +23 more
core +1 more source
Progesterone Resistance in Endometriosis [PDF]
Endometriosis is characterised by the presence of endometrium-like tissue on the pelvis and other organs. Progesterone resistance due to suppressed progesterone receptor (PGR) expression and action is a general feature of endometriosis and is a cause of ...
Jayasree Sengupta +3 more
core +1 more source
Background In previous retrospective studies, low serum progesterone level on the embryo transfer day is associated with lower clinical pregnancy and ongoing pregnancy rates.
Lin Haiyan +5 more
doaj +1 more source
Background and Aims Preterm birth (PTB) is the leading cause of perinatal mortality and morbidity, progesterone is one of the main hormones to maintain a normal pregnancy.
Soudabeh Kazemi Aski +5 more
doaj +1 more source
ObjectiveTo investigate the impact of the progesterone concentration on the human chorionic gonadotropin (hCG) trigger day on clinical outcomes with an antagonist protocol.MethodsThe retrospective cohort study included a total of 1,550 fresh autologous ...
Jianing Xu +3 more
doaj +1 more source
Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett +13 more
core +1 more source
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone
Whether and how innate antiviral response is regulated by humoral metabolism remains enigmatic. We show that viral infection induces progesterone via the hypothalamic-pituitary-adrenal axis in mice.
Shan Su +12 more
doaj +1 more source
Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]
Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
Sebire, Neil +46 more
core +2 more sources
Background: Luteal phase deficiency is common in assisted reproductive technology and is characterized by inadequate progesterone production. Various studies have shown that administration of progesterone in fresh embryo transfer cycles increases the ...
Samaneh Jalaliani +4 more
doaj +1 more source

