Non-genomic mechanisms of progesterone action in the brain
Frontiers in Neuroscience, 2013 Progesterone is a gonadal steroid hormone whose physiological effects extend well beyond the strict confines of reproductive function. In fact, progesterone can have important effects on a variety of tissues, including the bone, the heart and the brain ...
Meharvan Singh, Chang Su
exaly +3 more sources
Endometrial Progesterone and Estrogen Receptors in Relation to Hormonal Levels in Women with Unexplained Recurrent Miscarriage [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2023 Objective Recurrent miscarriage has been linked to hormonal disturbance due to dysregulation of its receptors rather than to the availability of the hormone.
Ihab Adel Gomaa +4 more
doaj +1 more source
The Neandertal Progesterone Receptor [PDF]
Molecular Biology and Evolution, 2020 Abstract The hormone progesterone is important for preparing the uterine lining for egg implantation and for maintaining the early stages of pregnancy. The gene encoding the progesterone receptor (PGR) carries introgressed Neandertal haplotypes with two missense substitutions and a mobile Alu element.
Hugo Zeberg, Janet Kelso, Svante Pääbo
openaire +2 more sources
Immunohistochemical expression of progesterone receptor and C-erb-B2 in cervical squamous cell carcinoma and epithelial dysplasia [PDF]
Journal of Clinical and Investigative Surgery, 2021 Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results.
Emine Zeynep Tarini +1 more
doaj +1 more source
Expression of female sex hormone receptors and its relation to clinicopathological characteristics and prognosis of lung adenocarcinoma [PDF]
Journal of Pathology and Translational Medicine, 2020 Background Adenocarcinoma (ADC) of the lung exhibits different clinicopathological characteristics in men and women. Recent studies have suggested that these differences originate from the expression of female sex hormone receptors in tumor cells.
Jin Hwan Lee +2 more
doaj +1 more source
Progestin receptor-mediated reduction of anxiety-like behavior in male rats. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known progesterone can have anxiolytic-like effects in animals in a number of different behavioral testing paradigms. Although progesterone is known to influence physiology and behavior by binding to classical intracellular ...
Catherine J Auger, Robin M Forbes-Lorman
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Analysis of the molecular subtypes of preoperative core needle biopsy and surgical specimens in invasive breast cancer [PDF]
Journal of Pathology and Translational Medicine, 2020 Background Accurate molecular classification of breast core needle biopsy (CNB) tissue is important for determining neoadjuvant systemic therapies for invasive breast cancer.
Ye Sul Jeong +5 more
doaj +1 more source
Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland [PDF]
Archives of Biological Sciences, 2011 The nature and extent of estrogen and progesterone action on the lacrimal gland is not known, and neither are the targets for their action. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal glands in both sexes
Gligorijević Jasmina +2 more
doaj +1 more source
Molecular Pain, 2022 Orofacial pain disorders are predominately experienced by women. Progesterone, a major ovarian hormone, is neuroprotective and antinociceptive. We recently reported that progesterone attenuates estrogen-exacerbated orofacial pain behaviors, yet it ...
Rebecca S Hornung +4 more
doaj +1 more source
Data in Brief, 2020 A previous investigation showed that the endometrium normalized in women with endometrial hyperplasia after three months treatment with high dose levonorgestrel IUS (intrauterine system) [1]. The effect was maintained even if immunohistochemical analyses
Natalia Smaglyukova +3 more
doaj +1 more source