Results 31 to 40 of about 272,686 (306)

Transdermal Delivery of Bioidentical Progesterone with a Steroid 5α-Reductase Inhibitor (Dutasteride): a Pilot Study

Journal of Pharmacy & Pharmaceutical Sciences, 2011
Purpose: Bioavailability of transdermal progesterone is low and variable. This may be attributed to transdermal metabolism by the 5α-reductase enzymes or the direct transport to the saliva. The objective of the current study was to evaluate the effect of
sara Zargar-Shoshtari, Hannaneh Wahhabaghei, Abdolrasoul Mehrsai, Jingyuan Wen, Raid Alany   +4 more
doaj   +1 more source

Steroid hormone bioavailability is controlled by the lymphatic system

Scientific Reports, 2021
The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restriction, and in
Rahel Klossner, Michael Groessl, Nadine Schumacher, Michaela Fux, Geneviève Escher, Sophia Verouti, Heidi Jamin, Bruno Vogt, Markus G. Mohaupt, Carine Gennari-Moser   +9 more
doaj   +1 more source

Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females. [PDF]

PLoS Pathogens, 2016
Over 100 million women use progesterone therapies worldwide. Despite having immunomodulatory and repair properties, their effects on the outcome of viral diseases outside of the reproductive tract have not been evaluated.
Olivia J Hall, Nathachit Limjunyawong, Meghan S Vermillion, Dionne P Robinson, Nicholas Wohlgemuth, Andrew Pekosz, Wayne Mitzner, Sabra L Klein   +7 more
doaj   +1 more source

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett, Richter, Dagmar-Ulrike, Volker Briese, Jeschke, Udo, Klaus Friese, Ioannis Mylonas, Annett Streu, Udo Jeschke, Briese, Volker, Mylonas, Ioannis, Müller, Heiner, Dagmar-Ulrike Richter, Friese, Klaus, Heiner Müller   +13 more
core   +1 more source

Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]

, 2012
Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
Sebire, Neil, Andrew Shennan, Thornton, S, Thornton, Steven, Petrou, Stavros, Marlow, N, Marlow, Neil, Robson Stephen, Tina Lavender, Neil Marlow, Neil Sebire, Robson, S, Sonia Whyte, Norman, Jane E., Norman, Jane E, Whyte, Sonia, Shennan, Andrew, Sebire Neil, Norrie John, Steven Thornton, Lavender Tina, Robson, Stephen, Stavros Petrou, Petrou, S, Lavender, Tina, Sebire, N, Thornton Steven, Marlow Neil, Whyte Sonia, John Norrie, Lavender, T, Stephen Robson, Bennett, Phillip R., Shennan, A, Sebire, Neil J., Bennett, Phillip, Bennett, P, Jane E Norman, Bennett Phillip, Petrou Stavros, Norrie, J, Norman, JE, Shennan Andrew, Phillip Bennett, Norman Jane E, Norrie, John, Whyte, S   +46 more
core   +2 more sources

The role of progesterone in the regulation of ciliary activity in the fallopian tube [PDF]

, 2009
The overall aim of this thesis was to investigate the distribution and regulation of membrane progesterone receptors (mPRs) that may be involved in regulating ciliary activity in the fallopian tube.
Nutu, Magdalena
core   +1 more source

Androgens Tend to Be Higher, but What about Altered Progesterone Metabolites in Boys and Girls with Autism?

Life, 2022
Background: Evidence exists that steroid hormones are altered in individuals with autism, especially androgens. Despite lower prevalence in girls than boys, evidence of potential alterations in progesterone metabolites is sparse, so the aim of this study
Benedikt Gasser, Johann Kurz, Genevieve Escher, Hiten D. Mistry, Markus G. Mohaupt   +4 more
doaj   +1 more source

The GABAA antagonist bicuculline attenuates progesterone-induced memory impairments in middle-aged ovariectomized rats

Frontiers in Aging Neuroscience, 2015
In women, high levels of natural progesterone have been associated with detrimental cognitive effects via the maternal amnesia phenomenon as well as in controlled experiments.
B. Blair Braden, B. Blair Braden, B. Blair Braden, Melissa L. Kingston, Elizabeth eWhitton, Courtney N. Lavery, Candy W.S. Tsang, Heather Allyson Bimonte-Nelson, Heather Allyson Bimonte-Nelson   +8 more
doaj   +1 more source

Effect of slightly elevated progesterone on hCG trigger day on clinical pregnancy rate in GnRH-ant IVF/ICSI cycles

Reproductive Health, 2022
Background It was been agreed that significantly elevated progesterone level on the hCG trigger day have detrimental effect on clinical outcomes in IVF/ICSI cycles.
Jing Zhao, Jie Hao, Bin Xu, Yonggang Wang, Yanping Li   +4 more
doaj   +1 more source

N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]

, 2004
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V., Friese, K., Richter, D.-U., Gundel, G., Mylonas, I., Unverzagt, C., Jeschke, U., Müller, H., Streu, A.   +8 more
core   +1 more source