Results 31 to 40 of about 413,118 (356)

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett, Richter, Dagmar-Ulrike, Volker Briese, Jeschke, Udo, Klaus Friese, Ioannis Mylonas, Annett Streu, Udo Jeschke, Briese, Volker, Mylonas, Ioannis, Müller, Heiner, Dagmar-Ulrike Richter, Friese, Klaus, Heiner Müller   +13 more
core   +1 more source

Progesterone and neuroprotection [PDF]

Hormones and Behavior, 2013
Numerous studies aimed at identifying the role of estrogen on the brain have used the ovariectomized rodent as the experimental model. And while estrogen intervention in these animals has, at least partially, restored cholinergic, neurotrophin and cognitive deficits seen in the ovariectomized animal, it is worth considering that the removal of the ...
Meharvan, Singh, Chang, Su
openaire   +2 more sources

Sexual Absorption of Vaginal Progesterone: A Randomized Control Trial

International Journal of Endocrinology, 2015
Objective. To determine if sexual intercourse reduces absorption of vaginal progesterone gel in women and to determine if progesterone is absorbed by the male during intercourse. Study Design.
Kathryn S. Merriam, Kristina A. Leake, Mollie Elliot, Michelle L. Matthews, Rebecca S. Usadi, Bradley S. Hurst   +5 more
doaj   +1 more source

Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone

Signal Transduction and Targeted Therapy, 2022
Whether and how innate antiviral response is regulated by humoral metabolism remains enigmatic. We show that viral infection induces progesterone via the hypothalamic-pituitary-adrenal axis in mice.
Shan Su, Duo Hua, Jin-Peng Li, Xia-Nan Zhang, Lei Bai, Li-Bo Cao, Yi Guo, Ming Zhang, Jia-Zhen Dong, Xiao-Wei Liang, Ke Lan, Ming-Ming Hu, Hong-Bing Shu   +12 more
doaj   +1 more source

Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization [PDF]

, 2011
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright @ 2011 Spandidos Publications Ltd.A vital function of the human placenta is to produce steroid hormones such as ...
Karteris, E, Zachariades, E, Foster, H, Goumenou, A, Thomas, P, Rand-Weaver, M, null Karteris   +6 more
core   +1 more source

Transdermal Delivery of Bioidentical Progesterone with a Steroid 5α-Reductase Inhibitor (Dutasteride): a Pilot Study

Journal of Pharmacy & Pharmaceutical Sciences, 2011
Purpose: Bioavailability of transdermal progesterone is low and variable. This may be attributed to transdermal metabolism by the 5α-reductase enzymes or the direct transport to the saliva. The objective of the current study was to evaluate the effect of
sara Zargar-Shoshtari, Hannaneh Wahhabaghei, Abdolrasoul Mehrsai, Jingyuan Wen, Raid Alany   +4 more
doaj   +1 more source

Steroid hormone bioavailability is controlled by the lymphatic system

Scientific Reports, 2021
The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restriction, and in
Rahel Klossner, Michael Groessl, Nadine Schumacher, Michaela Fux, Geneviève Escher, Sophia Verouti, Heidi Jamin, Bruno Vogt, Markus G. Mohaupt, Carine Gennari-Moser   +9 more
doaj   +1 more source

Progesterone Increases Bifidobacterium Relative Abundance during Late Pregnancy.

Cell Reports, 2019
Gestation is accompanied by alterations in the microbial repertoire; however, the mechanisms driving these changes are unknown. Here, we demonstrate a dramatic shift in the gut microbial composition of women and mice during late pregnancy, including an ...
M. Nuriel-Ohayon, Hadar Neuman, O. Ziv, Anna Belogolovski, Yiftah Barsheshet, N. Bloch, Atara Uzan, Roey Lahav, A. Peretz, S. Frishman, M. Hod, E. Hadar, Y. Louzoun, O. Avni, O. Koren   +14 more
semanticscholar   +1 more source

Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]

, 2010
This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Reynolds, A, Stenbeck, G, Karteris, E, Foster, H, Thomas, P, Dong, J   +5 more
core   +1 more source

Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT) : a randomized, double-blind, placebo-controlled study and meta-analysis EDITORIAL COMMENT [PDF]

, 2009
Women with twin pregnancy are at high risk of spontaneous preterm delivery. Three large randomized trials have shown that progesterone reduces the rate of preterm delivery in high-risk singleton pregnancies, although evidence of significant reduction in ...
Thornton, J.G., Thornton, James G., Thornton, Steven, Mires, Gary, Tydeman, Graham, Norman, Jane E., MacTier, H., Cooper, Sarah, Mactier, Helen, Martin, B., Norman, Jane E, Sturgiss, Stephen, MacKenzie, F., Mackenzie, Fiona, MacLennan, Graeme, Neilson, J.P., Danielian, P., Mires, G., Owen, Philip, Hanretty, Kevin, Calder, Andrew, Neilson, James P., Tydeman, G., Calder, A., Thornton, S., Thornton, James G, Danielian, Peter, Norman, J.E., Hanretty, K., Neilson, James P, Martin, Bill, Cooper, S., Norrie, J., Owen, P., Sturgiss, S., MacLennan, G., Norrie, John   +36 more
core   +1 more source