Results 11 to 20 of about 21,720 (281)

Effects of oral contraceptives on metabolic parameters in adult premenopausal women: a meta-analysis

open access: yesEndocrine Connections, 2020
Objective: To estimate the effect of oral contraceptives (OC) containing di fferent progestins on parameters of lipid and carbohydrate metabolism through a systematic review and meta-analysis. Patients and methods: Premenopausal women aged 18 or older,
Lina S Silva-Bermudez   +6 more
doaj   +1 more source

Therapeutic options of endometrial hyperplasia management. Current recommendations and prospective directions of treatment

open access: yesРепродуктивная эндокринология, 2021
Endometrial hyperplasia (EH) is a pathological condition characterized by proliferation of the endometrial glands with an increase in the glands/stroma ratio compared to normal proliferative endometrium. EH is a precursor to the development of one of the
T.F. Tatarchuk   +5 more
doaj   +1 more source

Endometrial hyperplasia and progesterone resistance: a complex relationship

open access: yesRUDN Journal of Medicine, 2023
The endometrium is one of the most dynamic tissues that constantly undergoes changes during the menstrual cycle in women of the reproductive period. All these processes take place mainly under the influence of steroid hormones that are produced in the ...
Mekan R. Orazov   +2 more
doaj   +1 more source

Pharmaceutical-technological aspects of therapeutic systems for hormonal contraception [PDF]

open access: yesArhiv za farmaciju, 2016
The use of therapeutic systems for hormonal contraception (TSHC) represents an important alternative approach for prevention of unintended pregnancies in comparison to oral hormonal contraceptives, whereby the risk of gastrointestinal adverse effects ...
Đekić Ljiljana, Primorac Marija
doaj   +1 more source

Fertility preservation in breast cancer with oral progestin: is it an option? A pilot study

open access: yesEinstein (São Paulo), 2021
Objective To compare the effectiveness of oral progestins and injectable gonadotropin-releasing hormone antagonist medication in cancer fertility preservation in patients with breast cancer.
Renato de Oliveira   +5 more
doaj   +2 more sources

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]

open access: yes, 2009
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia   +9 more
core   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

open access: yes, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal   +46 more
core   +1 more source

Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]

open access: yes, 2009
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus   +6 more
core   +1 more source

The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]

open access: yes, 2017
Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D   +12 more
core   +3 more sources

Clinical Efficacy, Pharmacokinetics, and Safety of the Available Medical Options in the Treatment of Endometriosis-Related Pelvic Pain: A Scoping Review

open access: yesPharmaceuticals, 2023
Background: In this scoping review, we sought to identify published studies evaluating the drugs currently used in the treatment of endometriosis-related pelvic pain, with reflection on their chemical properties, pharmacokinetics, safety profile, and ...
Mislav Mikuš   +4 more
doaj   +1 more source

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