Effects of oral contraceptives on metabolic parameters in adult premenopausal women: a meta-analysis
Objective: To estimate the effect of oral contraceptives (OC) containing di fferent progestins on parameters of lipid and carbohydrate metabolism through a systematic review and meta-analysis. Patients and methods: Premenopausal women aged 18 or older,
Lina S Silva-Bermudez +6 more
doaj +1 more source
Endometrial hyperplasia (EH) is a pathological condition characterized by proliferation of the endometrial glands with an increase in the glands/stroma ratio compared to normal proliferative endometrium. EH is a precursor to the development of one of the
T.F. Tatarchuk +5 more
doaj +1 more source
Endometrial hyperplasia and progesterone resistance: a complex relationship
The endometrium is one of the most dynamic tissues that constantly undergoes changes during the menstrual cycle in women of the reproductive period. All these processes take place mainly under the influence of steroid hormones that are produced in the ...
Mekan R. Orazov +2 more
doaj +1 more source
Pharmaceutical-technological aspects of therapeutic systems for hormonal contraception [PDF]
The use of therapeutic systems for hormonal contraception (TSHC) represents an important alternative approach for prevention of unintended pregnancies in comparison to oral hormonal contraceptives, whereby the risk of gastrointestinal adverse effects ...
Đekić Ljiljana, Primorac Marija
doaj +1 more source
Fertility preservation in breast cancer with oral progestin: is it an option? A pilot study
Objective To compare the effectiveness of oral progestins and injectable gonadotropin-releasing hormone antagonist medication in cancer fertility preservation in patients with breast cancer.
Renato de Oliveira +5 more
doaj +2 more sources
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia +9 more
core +1 more source
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal +46 more
core +1 more source
Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus +6 more
core +1 more source
The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]
Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D +12 more
core +3 more sources
Background: In this scoping review, we sought to identify published studies evaluating the drugs currently used in the treatment of endometriosis-related pelvic pain, with reflection on their chemical properties, pharmacokinetics, safety profile, and ...
Mislav Mikuš +4 more
doaj +1 more source

