Results 31 to 40 of about 10,432 (237)

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

International Journal of Cancer, EarlyView.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley, Fiona Caristo, Katrina Spilsbury, Sallie‐Anne Pearson, Peter Donovan, Michael D. Coory, Christopher B. Steer, Susan J. Jordan   +7 more
wiley   +1 more source

Progestins in the symptomatic management of endometriosis: a meta-analysis on their effectiveness and safety

BMC Women's Health, 2022
Background Endometriosis is a complex chronic disease that affects approximately 10% of women of reproductive age worldwide and commonly presents with pelvic pain and infertility.
Jon-Benay Mitchell, Sarentha Chetty, Fatima Kathrada   +2 more
doaj   +1 more source

Progesterone and Its Metabolites Play a Beneficial Role in Affect Regulation in the Female Brain

Pharmaceuticals, 2023
Premenstrual dysphoric disorder is a female affective disorder that is defined by mood symptoms. The condition is linked to unstable progesterone concentrations.
Małgorzata Stefaniak, Ewa Dmoch-Gajzlerska, Katarzyna Jankowska, Artur Rogowski, Anna Kajdy, Radosław B. Maksym   +5 more
doaj   +1 more source

Metroplasty before IVF in women with a T‐shaped uterus: A clinical challenge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract A T‐shaped uterus is a uterine malformation, which can be either congenital or acquired, potentially impairing fertility and increasing the risk of miscarriage. Diagnosis primarily relies on three‐dimensional ultrasound and hysteroscopy. Hysteroscopic metroplasty is the standard surgical intervention aimed at restoring normal uterine anatomy ...
Fabio Barra, Irene Gazzo, Alessandro Favilli, Consuelo Russo, Giulia Monaco, Franco Alessandri, Sandro Gerli, Luis Alonso Pacheco, Caterina Exacoustos, Simone Ferrero   +9 more
wiley   +1 more source

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Suppression of progesterone by influenza A virus mediates adverse maternal and fetal outcomes in mice

mBio
Influenza A virus infection during pregnancy can cause adverse maternal and fetal outcomes but the mechanism responsible remains elusive. Infection of outbred mice with 2009 H1N1 at embryonic day (E) 10 resulted in significant maternal morbidity ...
Patrick S. Creisher, Maclaine A. Parish, Jun Lei, Jin Liu, Jamie L. Perry, Ariana D. Campbell, Morgan L. Sherer, Irina Burd, Sabra L. Klein   +8 more
doaj   +1 more source

Potential alternative progestin therapy for low-grade endometrial stromal sarcoma: A case report

Gynecologic Oncology Reports, 2020
Low-grade endometrial stromal sarcoma (LG-ESS) is a rare uterine tumor that sometimes recurs and advances. Hormonal treatment, especially high-dose progestins and aromatase inhibitors (AIs), has demonstrated efficacy against these tumors.
Shoji Maenohara, Takahiro Fujimoto, Masao Okadome, Kenzo Sonoda, Kenichi Taguchi, Toshiaki Saito   +5 more
doaj   +1 more source

Development of Simultaneous Determination Method of a Pregnan Steroid with Gestagenic Activity – Gestobutanoil and Two its Metabolites in Rat Serum

Разработка и регистрация лекарственных средств, 2021
Introduction. Gestobutanoil is a synthetic pregnane steroid with gestagenic activity. Gestobutanoil has two pharmacologically active metabolites (AMOL and megestrol acetate). This implies the need for a detailed study of the kinetics of metabolites.
E. S. Stepanova, L. M. Makarenkova, S. V. Goryainov, T. A. Fedotcheva, N. L. Shimanovsky   +4 more
doaj   +1 more source

Coexisting adenomyosis in endometriosis: Similar pain and quality of life, with longer bleeding and bowel symptoms—A comparative cross‐sectional study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare pain, menstrual flow, and quality of life (QoL) between women undergoing surgery for endometriosis only compared with women with endometriosis and coexisting adenomyosis. Methods A cross‐sectional study, set in two tertiary hospitals, of reproductive‐aged women (18–50 years) with a preoperative imaging diagnosis of ...
Mariana Matzenbacher Brunoro, Ana Clara Pimenta Servidoni, Sofia Di Nur Wakabayashi, Camila Rebeque Dagola, Marina Paula Andres, Mauricio Simoes Abrao   +5 more
wiley   +1 more source

Association of novel intra‐cesarean post‐placental intrauterine device insertion techniques, and early ultrasound, with expulsion rates and strings visibility: A prospective exploratory study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess an innovative technique of intra‐cesarean post‐placental insertion of the Copper T380A IUD (CPPIUD), and explore the role of predischarge ultrasound with replacement of low‐lying IUDs. Methods We conducted a prospective observational study at Princess Marina Hospital, Gaborone, Botswana, from May 31, 2023, to April 3, 2024.
Kyungu M. Kime, Liza Bazzett‐Matabele, G. Justus Hofmeyr   +2 more
wiley   +1 more source