Results 41 to 50 of about 11,052 (225)

Pelvic Ultrasound for Predicting Endometrial Neoplasia in Premenopausal Abnormal Uterine Bleeding

Journal of Ultrasound in Medicine, EarlyView.
Objectives Although ultrasound is the first line imaging modality for abnormal uterine bleeding (AUB), there is a lack of consensus on its predictiveness for premenopausal endometrial pathology. This study aims to determine the predictiveness of pelvic ultrasound for endometrial neoplasia and cancer precursor lesions in premenopausal patients ...
Jessica Grubman, Delaina Bling, Haania Kakwan, Shubhangi Mehra, April Gorman, Alicia Kiszka, Diego H. Castrillon, Elysia Moschos   +7 more
wiley   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Varicose veins of the small pelvis and pelvic congestion syndrome. A differentiated approach: the choice of method of contraception, treatment, prevention

Репродуктивная эндокринология, 2017
The article considers the main points that affect the quality of life of women with varicose veins of small pelvis with congestion and without it, in particular the use of hormonal methods of contraception, and also discussed the issues of diagnostics ...
А. Н. Григоренко, А. Б. Гордийчук   +1 more
doaj   +1 more source

Progesterone, Progestins, and the Heart

Reviews in Cardiovascular Medicine, 2010
All combination hormone replacement regimens contain estrogen and a progestational agent. The Women's Health Initiative trial demonstrated that taking the combination of conjugated estrogen and medroxyprogesterone resulted in a higher risk of myocardial infarction and stroke in the study population.
Paula, Bernstein, Gerald, Pohost
openaire   +3 more sources

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

A Narrative Review of Progestin-Primed Ovarian Stimulation Protocols in Ovaries: Current Trends and Perspectives

Clinical and Experimental Obstetrics & Gynecology
Objective: This review aimed to provide an updated overview of progestin-primed ovarian stimulation (PPOS) outcomes across different patient groups, particularly in egg donation, fertility preservation, preimplantation genetic testing (
María Cerrillo, Inés Pérez-Zabala, Eduardo Goiry   +2 more
doaj   +1 more source

Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Sex hormone preparations are widely used in obstetrics for the treatment of infertility and miscarriage. Possible adverse effect of sex hormone preparations during pregnancy is their potential adverse impact on the hepatobiliary system.
Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova   +5 more
doaj   +1 more source

INFLUENCE OF CHRONIC NEUROGENIC PAIN ON LOCAL LEVELS OF SEX HORMONES AND RECEPTORS IN SKIN, TUMOR AND PERIFOCAL AREA IN MALE MICE WITH TRANSPLANTABLE В16/F10 MELANOMA

Сибирский онкологический журнал, 2020
Local synthesis and metabolism of sex hormones allow the skin to regulate autonomously both nociceptive reactions and proliferative processes in various pathologies.
E. M. Frantsiyants, V. A. Bandovkina, I. M. Kotieva, I. V. Kaplieva, L. K. Trepitaki, I. V. Neskubina, E. I. Surikova   +6 more
doaj   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Current trends in the research of the etiopathogenesis and treatment of endometriosis

Клинический разбор в общей медицине
Relevance. Endometriosis is a chronic disease characterized by the ectopic localization of endometrial tissue and is widely prevalent among women of reproductive age (up to 9%).
Aksinya P. Vasina, Anna M. Kudashkina, Daniil Yu. Shubin, Natalia A. Andreeva, Yulia M. Matyavina   +4 more
doaj   +1 more source