Results 31 to 40 of about 140,654 (50)

Human Calmodulin Mutations

open access: yesFrontiers in Molecular Neuroscience, 2018
Fluxes of calcium (Ca2+) across cell membranes enable fast cellular responses. Calmodulin (CaM) senses local changes in Ca2+ concentration and relays the information to numerous interaction partners.
Helene H. Jensen   +3 more
doaj   +1 more source

A trigger for opioid misuse: Chronic pain and stress dysregulate the mesolimbic pathway and kappa opioid system

open access: yesFrontiers in Neuroscience, 2016
Pain and stress are protective mechanisms essential in avoiding harmful or threatening stimuli and ensuring survival. Despite these beneficial roles, chronic exposure to either pain or stress can lead to maladaptive hormonal and neuronal modulations that
Nicolas Massaly   +4 more
doaj   +1 more source

Age-related changes in dynamic postural control and attentional demands are minimally affected by local muscle fatigue.

open access: yesFrontiers in Aging Neuroscience, 2016
Normal aging results in alterations in the visual, vestibular and somtaosensory systems, which in turn modify the control of balance. Muscle fatigue may exacerbate these age-related changes in sensory and motor functions, and also increase the ...
Anthony eRemaud   +4 more
doaj   +1 more source

Tau oligomers: the toxic player at synapses in Alzheimer’s disease

open access: yesFrontiers in Cellular Neuroscience, 2015
Alzheimer’s disease (AD) is a progressive disorder in which the most noticeable symptoms are cognitive impairment and memory loss. However, the precise mechanism by which those symptoms develop remains unknown.
Marcos Jair Guerrero-Munoz   +2 more
doaj   +1 more source

Evaluation of clinical comorbidities in cognitively impaired patients with depressive symptoms

open access: yesDementia & Neuropsychologia
In demented patients, depressive symptoms as well as cognition and clinical comorbidities can interact and induce a complex condition of severity and handicap. Objective: The objective of this study was to evaluate the influence of depressive symptoms in
Rossana Maria Russo Funari   +4 more
doaj   +1 more source

Pro-sociality and Strategic Reasoning in Economic Decisions

open access: yesFrontiers in Behavioral Neuroscience, 2015
We study the relationship between pro-social preferences and strategic reasoning. These aspects are typically studied separately but little is known about their joint distribution.
Benito eArrunada   +2 more
doaj   +1 more source

The Thalamostriatal System in Normal and Diseased States

open access: yesFrontiers in Systems Neuroscience, 2014
Because of our limited knowledge of the functional role of the thalamostriatal system, this massive network is often ignored in models of the pathophysiology of brain disorders of basal ganglia origin, such as Parkinson’s disease.
Yoland eSmith   +7 more
doaj   +1 more source

Filopodia: A Rapid Structural Plasticity Substrate for Fast Learning

open access: yesFrontiers in Synaptic Neuroscience, 2017
Formation of new synapses between neurons is an essential mechanism for learning and encoding memories. The vast majority of excitatory synapses occur on dendritic spines, therefore, the growth dynamics of spines is strongly related to the plasticity ...
Ahmet S. Ozcan
doaj   +1 more source

Compensatory recovery after multisensory stimulation in hemianopic patients: behavioral and neurophysiological components

open access: yesFrontiers in Systems Neuroscience, 2016
Lateralized post-chiasmatic lesions of the primary visual pathway result in loss of visual perception in the field retinotopically corresponding to the damaged cortical area.
Paolo Antonino Grasso   +2 more
doaj   +1 more source

Dopamine regulation of social choice in a monogamous rodent species

open access: yesFrontiers in Behavioral Neuroscience, 2009
There is growing appreciation that social decision making in humans is strongly influenced by hedonic and emotional processing. The field of social neuroeconomics has shown that neural systems important for reward are associated with social choice and ...
Brandon J Aragona, Zuoxin Wang
doaj   +1 more source

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