Effects of Ginsenoside Rb1 on the Crosstalk between Intestinal Stem Cells and Microbiota in a Simulated Weightlessness Mouse Model. [PDF]
Int J Mol SciZong B +6 more
europepmc +2 more sources
Study of histopathological and molecular changes of rat kidney under simulated weightlessness and resistance training protective effect. [PDF]
PLoS ONE, 2011 To explore the effects of long-term weightlessness on the renal tissue, we used the two months tail suspension model to simulate microgravity and investigated the simulated microgravity on the renal morphological damages and related molecular mechanisms.
Ye Ding +12 more
doaj +2 more sources
Artificial Gravity as a Bone Loss Countermeasure in Simulated Weightlessness
The FASEB Journal, 2007 The impact of microgravity on the human body is a significant concern for space travelers. We report here initial results from a pilot study designed to explore the utility of artificial gravity (AG) as a countermeasure to the effects of microgravity, specifically to bone loss.
Scott M. Smith +6 more
openalex +4 more sources
Angelicae dahuricae radix alleviates simulated microgravity induced bone loss by promoting osteoblast differentiation [PDF]
npj MicrogravityBone loss caused by long-duration spaceflight seriously affects the skeletal health of astronauts. There are many shortcomings in currently available treatments for weightlessness-induced bone loss.
Xuechao Liang +10 more
doaj +2 more sources
Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids [PDF]
BiomoleculesMicrogravity is one of the main stressors that astronauts are exposed to during space missions. This condition has been linked to many disorders, including those that feature dysfunctional immune homeostasis and inflammatory damage.
Marina Fava +5 more
doaj +2 more sources
Simulated weightlessness affects the expression and activity of neuronal nitric oxide synthase in the rat brain. [PDF]
Oncotarget, 2017 Yoon N, Na K, Kim HS.
europepmc +3 more sources
Simulated microgravity affects carrageenan-induced inflammation process in rats [PDF]
Pharmacia, 2023 Weightlessness significantly impacts physiological systems. In the current study, we investigate the effects of 7 days exposure of rats to simulated microgravity (using a modified rat-modeled random positioning machine, working with four experimental ...
Viktor Yotov +5 more
doaj +3 more sources
Frontiers in Pharmacology, 2023 Microgravity experienced during space flight is known to exert several negative effects on the learning ability and memory of astronauts. Few effective strategies are currently available to counteract these effects.
Ning Jiang +8 more
doaj +1 more source
Cell proliferation, cell shape, and microtubule and cellulose microfibril organization of tobacco BY-2 cells are not altered by exposure to near weightlessness in space [PDF]
, 2009 The microtubule cytoskeleton and the cell wall both play key roles in plant cell growth and division, determining the plant’s final stature. At near weightlessness, tubulin polymerizes into microtubules in vitro, but these microtubules do not self ...
Emons, A.M.C. +4 more
core +4 more sources
Stem Cells International, 2022 Objective. This study is aimed at screening the differential expression profiles of mRNA under weightlessness osteoporosis through high-throughput sequencing technology, as well as investigating the pathogenesis of weightlessness osteoporosis at the ...
Dong Wang +8 more
doaj +1 more source