Results 1 to 10 of about 1,315 (237)

Gastrointestinal motility in microgravity: a critical review of multi-level mechanisms and model-dependent effects [PDF]

Frontiers in Physiology
BackgroundGastrointestinal motility disturbances rank among the most frequently reported medical complications of spaceflight. Astronauts experience delayed gastric emptying, erratic small intestinal transit and reduced colonic propulsion. The underlying
Qian Niu, Tong Mu, Junhai Zhang, Yue Chen, Zhikun Guo, Yuanmin Zhu, Lin Li   +6 more
doaj   +2 more sources

Sensorimotor performance and haptic support in simulated weightlessness [PDF]

Experimental Brain Research, 2020
AbstractThe success of many space missions critically depends on human capabilities and performance. Yet, it is known that sensorimotor performance is degraded under conditions of weightlessness. Therefore, astronauts prepare for their missions in simulated weightlessness under water.
Freek Stulp, Michael Panzirsch, Stefan Schneider   +2 more
exaly   +5 more sources

Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress [PDF]

Drug Design, Development and Therapy
Yanli Wang,1,* Tian Chen,2,* Zhe Shi,3,* Lijinchuan Dong,1 Mengting Li,1 Bo Peng,1 Qi Li,1 Ruile Pan,4 Shuiming Xiao,1 Qing Yang,1 Ning Jiang,4 Xinmin Liu,4,5 Qin Hu,2 Ying Chen1 1Institute of Chinese Materia Medica, China Academy of Chinese ...
Wang Y, Chen T, Shi Z, Dong L, Li M, Peng B, Li Q, Pan R, Xiao S, Yang Q, Jiang N, Liu X, Hu Q, Chen Y   +13 more
doaj   +2 more sources

Multiple simulated spaceflight stressors impact cardiac fibrosis, calcium dynamics, immune function, cytokines and gene variants in rat, Rattus norvegicus. [PDF]

PLoS ONE
Space radiation and microgravity pose significant health risks for astronauts conducting deep space exploration. The impact of galactic cosmic radiation (GCR) and weightlessness alone, and their combined effects on cardiac disease, the immune system ...
Marek Lenarczyk, Amy Kronenberg, Andy Kwok, Alexander Borg, Ammar J Alsheikh, Angela J Mathison, Michael T Zimmermann, Samuel B R Lawton, Hershel Raff, Jeffrey Willey, Richard A Komorowski, Raul Urrutia, John E Baker   +12 more
doaj   +2 more sources

Effects of weightlessness on the cardiovascular system: a systematic review and meta-analysis [PDF]

Frontiers in Physiology
Background: The microgravity environment has a direct impact on the cardiovascular system due to the fluid shift and weightlessness that results in cardiac dysfunction, vascular remodeling, and altered Cardiovascular autonomic modulation (CAM ...
Rafaella Mendes Zambetta, Étore De Favari Signini, Gabriela Nagai Ocamoto, Gabriela Nagai Ocamoto, Aparecida Maria Catai, Nicoly Ribeiro Uliam, Emiliano Santarnecchi, Thiago Luiz Russo   +7 more
doaj   +2 more sources

Is the ICP pulse waveform P2/P1 ratio during -6° head-down tilt associated with relative VO2 peak? A non-invasive intracranial compliance monitoring approach [PDF]

Brain and Spine
Background: Spaceflights influence intracranial compliance (ICC). P2/P1 ratio, from the intracranial pressure (ICP) waveform, provides information about ICC. Additionally, non-invasive methods for ICC monitoring are needed for spaceflights.
Rafaella Mendes Zambetta, Étore De Favari Signini, Aparecida Maria Catai, Thainá Cristina Ramos dos Santos, Eloisa Soares Michaliski, Ana Karoline Nazario, Gabriela Nagai Ocamoto, Gustavo Frigieri, Thiago Luiz Russo   +8 more
doaj   +2 more sources

Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness

Frontiers in Physiology, 2023
Objective: Microgravity contributes to ocular injury yet the underlying mechanism remains unclear. This study aims to elucidate the mechanism behind choroidal circulation disorder and outer retinal degeneration in rats with simulated weightlessness ...
Yuxue Mu, Yuxue Mu, Dongyu Wei, Lilingxuan Yao, Xinyue Xu, Shaoheng Li, Ruidan Cao, Ruidan Cao, Tao Chen, Tao Chen, Zuoming Zhang   +10 more
doaj   +1 more source

Alteration Of Cytoskeleton Morphology And Gene Expression In Human Breast Cancer Cells Under Simulated Microgravity [PDF]

Cell Journal, 2020
Objective Weightlessness simulation due to the simulated microgravity has been shown to considerably affect behavior of tumor cells. It is aim of this study to evaluate characteristics of human breast cancer cells in this scaffold- free 3D culture model.
Florian Strube, Manfred Infanger, Markus Wehland, Xenia Delvinioti, Alexander Romswinkel, Carlo Dietz, Armin Kraus   +6 more
doaj   +1 more source

Evaluation of free-floating tracheal intubation in weightlessness via ice-pick position with a direct laryngoscopy and classic approach with indirect videolaryngoscopy

npj Microgravity, 2023
Long duration spaceflights to the Moon or Mars are at risk for emergency medical events. Managing a hypoxemic distress and performing an advanced airway procedure such as oro-tracheal intubation may be complicated under weightlessness due to ergonomic ...
Séamus Thierry, François Jaulin, Clément Starck, Philippe Ariès, Jan Schmitz, Steffen Kerkhoff, Cécile Isabelle Bernard, Matthieu Komorowski, Tobias Warnecke, Jochen Hinkelbein   +9 more
doaj   +1 more source

Land Lapse Phenomenon and Surface Subsidence Law of Shield Tunnel Passing Through Rock-Bearing Formation

Frontiers in Earth Science, 2022
When constructing subway tunnels in coastal cities, boulders with high strength and large volume are often encountered. A large number of engineering practices have shown that the existence of boulders will destroy the unity and homogeneity of the ...
Yu Guangming, Xia Pengju, Zhang Yongyi, Shi Qimeng, Lei Jun, Song Pengfei, Tan Zhiwen, Liu Hao, Chen Ze   +8 more
doaj   +1 more source