Results 31 to 40 of about 229,483 (161)

Tumor Necrosis Factor Alpha In Preeclampsia

, 2013
Pre-eclampsia is one of the most frequent complications of pregnancy, however, little is known about its aetiology. Insufficient adaptation of the decidual and intramyometrial portions of the spiral arterioles in preeclampsia results in reduced utero-placental blood flow, leading to local placental hypoxia.
Fozia A Patigaroo, Siddiqui, Anwar H, Gulat, Rajiv, ZehraMohsin   +3 more
openaire   +2 more sources

Single-cell multi-omics reveals the TNF-α activation threshold for Classical Monocytes by studying healthy donors and rheumatoid arthritis patients

Frontiers in Immunology
IntroductionTumor Necrosis Factor Alpha is a known pro-inflammatory cytokine that plays a key role in the pathogenesis of rheumatoid arthritis. Anti-cytokine therapies targeting Tumor Necrosis Factor Alpha have greatly succeeded in treating rheumatoid ...
Roman Perik-Zavodskii, Roman Perik-Zavodskii, Olga Perik-Zavodskaia, Saleh Alrhmoun, Saleh Alrhmoun, Julia Lopatnikova, Julia Lopatnikova, Alina Alshevskaya, Julia Zhukova, Julia Zhukova, Julia Shevchenko, Julia Shevchenko, Nadezhda Shkaruba, Natalia Sivitskaya, Shakir Suleimanov, Elizaveta Sheveleva, Kirill Nazarov, Fedor Kireev, Fedor Kireev, Alexey Sizikov, Elena Golikova, Sergey Sennikov, Sergey Sennikov   +22 more
doaj   +1 more source

Tumor Necrosis Factor Alpha in Amyotrophic Lateral Sclerosis: Friend or Foe?

Cells, 2021
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a massive neuroinflammatory reaction, which plays a key role in the progression of the disease.
Giulia Guidotti, Chiara Scarlata, Liliana Brambilla, Daniela Rossi   +3 more
doaj   +1 more source

Segmental vitiligo after infliximab use for rheumatoid arthritis - A case report [PDF]

Anais Brasileiros de Dermatologia, 2014
The tumor necrosis factor alpha is a cytokine related to immune and inflammatory processes by acting on different parts of the body. It is secreted by several cell types including macrophages, lymphocytes, monocytes, neutrophils, dendritic cells, among ...
Clarissa Luiza Dalla Bernardina Carvalho, Luciena Cegatto Martins Ortigosa   +1 more
doaj   +1 more source

Sinusitis in patients on tumor necrosis factor alpha inhibitors [PDF]

International Forum of Allergy & Rhinology, 2016
BackgroundTumor necrosis factor alpha (TNF‐α) inhibitors have revolutionized treatment of many inflammatory diseases. Sinusitis after initiation of TNF‐α inhibitors has been observed, but has not been well described in the literature. We aim to characterize the clinical features of sinusitis in patients on anti‐TNF‐α therapy.MethodsThis is a ...
Adam Honeybrook, Nikita Chapurin, Anjeni Keswani, Cynthia S. Wang, David W. Jang   +4 more
openaire   +3 more sources

Tumor necrosis factor alpha gene polymorphism in Serbian patients with sarcoidosis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Sarcoidosis is a multisystemic disease of unknown etiology. Genetic factors play a considerable role in the onset of the disease. Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine which plays an important role in the ...
Rađenović-Petković Tatjana, Pejčić Tatjana, Videnović-Ivanov Jelica, Jevtović-Stoimenov Tatjana, Janković Irena, Nastasijević-Borovac Desa, Radojković Danijela   +6 more
doaj   +1 more source

Targeted Cancer Therapy with Tumor Necrosis Factor-Alpha [PDF]

Biochemistry Insights, 2008
Tumor necrosis factor-alpha (TNF-α), a member of the TNF superfamily, was the first cytokine to be evaluated for cancer biotherapy. However, the clinical use of TNF-α is severely limited by its toxicity. Currently, TNF-α is administered only through locoregional drug delivery systems such as isolated limb perfusion and isolated hepatic perfusion.
Weibo Cai, Hao Hong, Zachary Kerner, Jiangtao Sun   +3 more
openaire   +3 more sources

Hubungan antara Tumor Necrosis Factor Alpha dengan Demam Berdarah Dengue

Sari Pediatri, 2016
Latar belakang. Sampai saat ini patogenesis demam berdarah dengue (DBD) belum dipahami secara sempurna. Pada kasus DBD didapatkan adanya peningkatan kadar TNF-α, sitokin yang poten dalam meningkatkan permeabilitas pembuluh darah.
Felix Candra Sutanto, Max F.J. Mantik, Vivekenanda Pateda   +2 more
doaj   +1 more source

Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model

Acta Cirúrgica Brasileira, 2022
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and colitis was induced on 20 rats
Cengiz Dibekoğlu, Oytun Erbaş
doaj   +1 more source

Expression of periostin in the epithelium of cholesteatoma with different degrees of ossicular chain destruction and its clinical value in predicting postoperative hearing recovery

BioMedical Engineering OnLine
Objectives To explore the expression of periostin in the epithelium of cholesteatoma with different destruction degrees of the ossicular chain and its clinical value in predicting postoperative hearing recovery.
Cuncun Xie, Xiaodong Jia, Shaoguang Ding, Xiaoli Ding, Guangke Wang, Hongjian Liu   +5 more
doaj   +1 more source