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Rules for biological regulation based on error minimization
The control of gene expression involves complex mechanisms that show large variation in design. For example, genes can be turned on either by the binding of an activator (positive control) or the unbinding of a repressor (negative control).
Atkinson+37 more
core +2 more sources
Genetics and activity inDrosophila melanogaster
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +4 more sources
Mouse genetics: Catalogue and scissors [PDF]
Phenotypic analysis of gene-specific knockout (KO) mice hasrevolutionized our understanding of in vivo gene functions. Asthe use of mouse embryonic stem (ES) cells is inevitable forconventional gene targeting, the generation of knockout miceremains a ...
Han-Woong Lee
doaj
The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton+44 more
core +2 more sources
A model for selection of eyespots on butterfly wings [PDF]
The development of eyespots on the wing surface of butterflies of the family Nympalidae is one of the most studied examples of biological pattern formation.However, little is known about the mechanism that determines the number and precise locations of ...
A Gierer+32 more
core +4 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
BackgroundPrevious observational studies have reported a possible association between circulating lipids and lipid-lowering drugs and male infertility (MIF), as well as the mediating role of circulating vitamin D.
Wei Li+6 more
doaj +1 more source
Meanings in the Process of Signification of Lancôme's Beauty Serum Advertisements [PDF]
Through this study, the writer aimed to find out how meanings are created in advertisements video. The three objectives of this study are to find out how meanings are created through verbal expressions, how the visual expressions of the advertisements ...
Kuntjara, E. H. (Esther)+1 more
core
Isolating and Quantifying the Role of Developmental Noise in Generating Phenotypic Variation [PDF]
Genotypic variation, environmental variation, and their interaction may produce variation in the developmental process and cause phenotypic differences among individuals. Developmental noise, which arises during development from stochasticity in cellular
Chiari, Ylenia+4 more
core +5 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source