Results 41 to 50 of about 12,134 (300)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Anaphylactic Reaction to Bee Stings in the Rural Areas of Gorgan City: Iran’s First Epidemiological Study of Hymenoptera-Induced Anaphylaxis

Journal of Pediatrics Review, 2019
Background: We aimed to determine the epidemiology of anaphylaxis to bee stings in the rural areas of Gorgan City, Iran.  Objectives: Anaphylaxis is a severe, life-threatening, diffuse or systemic hypersensitivity reaction with rapidly progressive ...
Mohammad Hasan Bemanian, Saba Arshi, Mohammad Nabavi, Morteza Fallahpour, Mohsen Aarabi, Maryam Karbasi, Vahid Ghobadidana, Mehdi Torabizadeh, Mohammad reza Honarvar, Seyed Ali Aghapour   +9 more
doaj  

Poisonous spiders and other venomous arthropods in Missouri [PDF]

, 1960
Caption title.Includes bibliographical ...
Wingo, Curtis W., 1915-
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

An outbreak of Portuguese man-of-war (Physalia physalis - Linnaeus, 1758) envenoming in Southeastern Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction Portuguese man-of-war, Physalia physalis (Linnaeus, 1758), are cnidarians capable of discharging intracellular organelles filled with venom, resulting in severe envenomation in humans. Methods We report the clinical and therapeutic aspects
Vidal Haddad Junior, Rossana Virga, Adriano Bechara, Fabio Lang da Silveira, Andre Carrara Morandini   +4 more
doaj   +1 more source

Beyond anaphylaxis: acute myocardial infarction with ischemic stroke after bee sting a case report

طب اورژانس ایران, 2023
Although Hymenoptera stings mostly present with benign local inflammation, they can also be fatal. The true incidence of fatal reactions is unknown as sudden deaths due to insect bites might be regarded as heart attacks or strokes.
Zainab Mehdi, Monica Gupta, Anish Garg, Narinder Kaur   +3 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1975
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1115/thumbnail ...

core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Special Adaptations of Orb Weavers and Prey [PDF]

, 1986
Orb weaving spiders have devised both webs and special devices for capturing prey. The prey have also evolved mechanisms for eluding spiders and for living with them.
Dorris, Peggy Rae
core   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source