Results 1 to 10 of about 215,084 (308)

cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]

, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core   +2 more sources

Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England [PDF]

, 2015
Concerns have been raised over breed-related health issues in purebred dogs, but reliable prevalence estimates for disorders within specific breeds are sparse.
Brodbelt, D C, Church, D B, McGreevy, P D, O'Neill, D G, Summers, J F, Thomson, P C   +5 more
core   +3 more sources

A Taxon-Specific and High-Throughput Method for Measuring Ligand Binding to Nicotinic Acetylcholine Receptors

Toxins, 2019
The binding of compounds to nicotinic acetylcholine receptors is of great interest in biomedical research. However, progress in this area is hampered by the lack of a high-throughput, cost-effective, and taxonomically flexible platform.
Christina N. Zdenek, Richard J. Harris, Sanjaya Kuruppu, Nicholas J. Youngman, James S. Dobson, Jordan Debono, Muzaffar Khan, Ian Smith, Mike Yarski, David Harrich, Charlotte Sweeney, Nathan Dunstan, Luke Allen, Bryan G. Fry   +13 more
doaj   +1 more source

Pretender punishment induced by chemical signalling in a queenless ant [PDF]

, 2002
Animal societies are stages for both conflict and cooperation. Reproduction is often monopolized by one or a few individuals who behave aggressively to prevent subordinates from reproducing (for example, naked mole-rats, wasps and ants).
Beard, R., Jones, G.R., Monnin, T., Ratnieks, F.L.W.   +3 more
core   +3 more sources

Border Terriers under primary veterinary care in England: demography and disorders [PDF]

, 2017
The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers receiving veterinary care in England using de ...
A Agresti, A Egenvall, A Gough, A Tvarijonaviciute, A-S Lequarré, AJ German, AR Boyko, BA Niemiec, BR Kirkwood, C Dedola, C Gorrel, D O'Neill, DD Sleator, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, EM Lund, EM Lund, ER Shore, F Mariani, FC Calboli, FE Taylor-Brown, FS Roedler, GJ Patronek, HF Proschowsky, HG Parker, HG Parker, ID Robertson, J Lipton, J Sampson, J Stavisky, J Summers, JF Summers, K Christensen, L Asher, L Kearsley-Fleet, LJ DeBowes, LM Collins, LM Collins, LT Glickman, LT Glickman, M Demirkiran, M Downes, M Ratsitorahina, MD Willard, MJ Mattin, OV Horst, P Bateson, P D’Aquila, P Sandøe, PC Bartlett, PD McGreevy, PE Holt, R Collins, R Johns, RA Packer, RK Wayne, S Acharya, T Lewis, V Black, VJ Adams, W Low   +66 more
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A Comparison of the Efficacy of Antivenoms and Varespladib against the In Vitro Pre-Synaptic Neurotoxicity of Thai and Javanese Russell’s Viper (Daboia spp.) Venoms

Toxins
The heterogeneity in venom composition and potency in disparate Eastern Russell’s viper (Daboia siamensis) populations has repercussions for the efficacy of antivenoms. This is particularly pronounced in geographical areas in which the venom of the local
Mimi Lay, Wayne C. Hodgson
doaj   +1 more source

Moral Luck and Deviant Causation [PDF]

, 2019
This paper discusses a puzzling tension in attributions of moral responsibility in cases of resultant moral luck: we seem to hold agents fully morally responsible for unlucky outcomes, but less-than-fully-responsible for unlucky outcomes brought about ...
Bernstein, Sara
core  

Crotalus tortugensis [PDF]

, 2004
Number of Pages: 5Integrative BiologyGeological ...
Beaman, Kent R., Spencer, Carol L.
core   +1 more source

Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms

Toxins, 2016
Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms.
Jordan Debono, Chip Cochran, Sanjaya Kuruppu, Amanda Nouwens, Niwanthi W. Rajapakse, Minami Kawasaki, Kelly Wood, James Dobson, Kate Baumann, Mahdokht Jouiaei, Timothy N. W. Jackson, Ivan Koludarov, Dolyce Low, Syed A. Ali, A. Ian Smith, Andrew Barnes, Bryan G. Fry   +16 more
doaj   +1 more source

Prescribing practices of primary-care veterinary practitioners in dogs diagnosed with bacterial pyoderma [PDF]

, 2014
Concern has been raised regarding the potential contributions of veterinary antimicrobial use to increasing levels of resistance in bacteria critically important to human health.
A Hillier, A Mateus, A Wayne, AD Radford, AD Watson, Anke Hendricks, B Kirkwood, C Noli, CP Murphy, David C Brodbelt, DL Wells, DW Scott, DW Scott, EJ Pleydell, EM Lund, FC Tenover, IS Mason, J Bannoehr, J Cd, Jennifer F Summers, JF Summers, JR Fitzgerald, JS Weese, K Gortel, K Odensvik, L Beco, L Beco, LA Hughes, LM Freeman, LS Barter, M Escher, M Rantala, N Murayama, National Organisation of Animal Health (Great Britain) (NOAH), OM Briggs, PB Hill, PB Hill, PJ Ihrke, RK Anderson, T Sasaki, VJ Adams, WM Sischo   +41 more
core   +2 more sources