Results 1 to 10 of about 171,196 (309)
Inhibition of mitochondrial complex III causes selective dopaminergic neurotoxicity by redox stress in Caenorhabditis elegans [PDF]
Redox BiologyEnvironmental factors including chemical exposures are important contributors to Parkinson's disease (PD). Nearly all well-validated chemicals involved in PD affect mitochondria, and the great majority of those identified inhibit mitochondrial complex I,
Javier Huayta +3 more
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Nanoparticles and Neurotoxicity
International Journal of Molecular Sciences, 2011 Humans are exposed to nanoparticles (NPs; diameter < 100 nm) from ambient air and certain workplaces. There are two main types of NPs; combustion-derived NPs (e.g., particulate matters, diesel exhaust particles, welding fumes) and manufactured or engineered NPs (e.g., titanium dioxide, carbon black, carbon nanotubes, silver, zinc oxide, copper oxide)
Tin Tin Win Shwe
exaly +3 more sources
Research Progress on Intervention of Natural Products from Plants in Neurotoxicity of Acrylamide [PDF]
Shipin Kexue, 2023 Acrylamide (ACR) is a common toxic substance in foods, which can cause serious damage to human organs and systems, especially the nervous system. At present, there are no appropriate measures to prevent and treat ACR neurotoxicity.
ZHANG Mengyu, ZHANG Yanqing, FANG Leilei, XIE Junbo, WEI Yinghao
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Pharmaceuticals, 2023 Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1 ...
Gabriela Becker +3 more
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Neuroinflammation in Bilirubin Neurotoxicity
Journal of Integrative Neuroscience, 2023 Bilirubin neurotoxicity is a serious consequence of hyperbilirubinemia, which is the most common disease of the neonatal period. Clinically, bilirubin neurotoxicity can result in motor deficit, auditory dysfunction, cerebral palsy, seizure and ...
Fanhui Zhang, Lihua Chen, Kewen Jiang
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Assessing the association between cefepime percentage free trough level and neurotoxicity
Antimicrobial Stewardship & Healthcare Epidemiology, 2022 Background: Cefepime has a known association with neurotoxicity due to its ability to cross the blood–brain barrier. The symptoms of neurotoxicity are highly variable.
Aleena Zia +3 more
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Postgraduate Medical Journal, 1979 Summary The peripheral and central neurotoxic effects of lithium carbonate are illustrated by 4 case histories. Lithium neurotoxicity is likely to be more common than the literature suggests. Neurological sequelae may be irreversible and may be associated with therapeutic serum levels. Prevention may be facilitated by more stringent case
P K, Newman, M, Saunders
openaire +2 more sources
Haematologica, 2021 Symptomatic methotrexate-related central neurotoxicity (MTX neurotoxicity) is a severe toxicity experienced during acute lymphoblastic leukemia (ALL) therapy with potential long-term neurologic complications.
Marion K. Mateos +18 more
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Neurotoxicity by Cefepime: Case-Control Study [PDF]
Journal of Neurocritical Care, 2014 Background: Cefepime is a fourth-generation cephalosporin widely used for empiric treatment of severe infections. Neurotoxicity by cefepime have been reported due to γ-aminobutyric acid A receptor inhibition or other mechanisms. The aim of this study was
Joong Koo Kang, Soon Bae Kim
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iScience, 2023 Summary: Excessive exposure to manganese (Mn) can cause neurological abnormalities, but the mechanism of Mn neurotoxicity remains unclear. Previous studies have shown that abnormal mitochondrial metabolism is a crucial mechanism underlying Mn ...
Shixuan Zhang +5 more
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