Results 1 to 10 of about 177,558 (313)

Negative myoclonus as a manifestation of cefepime neurotoxicity

Clinical Case Reports
Key Clinical Message Negative myoclonus may present in the early stages of cefepime neurotoxicity. Cefepime neurotoxicity typically presents as reduced consciousness, myoclonus, and seizures; however, negative myoclonus is uncommon.
Daichi Umemoto, Hirokazu Kuroda, Hiroaki Nishioka   +2 more
doaj   +2 more sources

Transient Contrast Neurotoxicity After Percutaneous Coronary Intervention Mimicking Subarachnoid Hemorrhage in a Patient With Chronic Kidney Disease

Clinical Medicine Insights: Case Reports, 2019
Transient contrast neurotoxicity is a rare but well-recognized complication of angiography that is due to neurotoxicity of the contrast agent. Patients with renal dysfunction may be inclined to develop contrast medium neurotoxicity due to delayed ...
Ersin Çagri Şimşek, Elif Ertürk, Roza Uçar, Artun Onat Yilmaz, Cenk Ekmekçi, İnan Mutlu, Cenk Sari   +6 more
doaj   +1 more source

Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

World Journal of Surgical Oncology, 2013
Background Oxaliplatin, an effective antineoplastic agent againstgastrointestinal tumors, can cause severe peripheral neurotoxicity, which seriously limits its clinical application.
Zhu Yanyun, Yang Junlan, Jiao Shunchang, Ji Tiefeng   +3 more
doaj   +1 more source

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

Molecules, 2017
Spirulina maxima is a microalgae which contains flavonoids and other polyphenols. Although Spirulina maxima 70% ethanol extract (SM70EE) has diverse beneficial effects, its effects on neurotoxicity have not been fully understood.
Eun-Jeong Koh, Young-Jin Seo, Jia Choi, Hyeon Yong Lee, Do-Hyung Kang, Kui-Jin Kim, Boo-Yong Lee   +6 more
doaj   +1 more source

Short-course metronidazole-induced reversible acute neurotoxicity in a renal transplant recipient

Saudi Journal of Kidney Diseases and Transplantation, 2018
Neurotoxic manifestations due to chronic metronidazole intake are well known, but neurotoxicity due to short-term use of metronidazole is very rare. We present a case of acute neurotoxicity due to short course of injectable metronidazole given in usual ...
Pavitra Manu Dogra, Anil Kumar Bhatt, Sanjay Kumar Agarwal, Dipankar Bhowmik   +3 more
doaj   +1 more source

Child with acute methotrexate related neurotoxicity: Can diffusion weighted MRI help??

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Background: Methotrexate is widely used chemotherapy especially in pediatric hematological malignancy. It may associate with acute neurotoxicity.
Ayda A. Youssef, Tarek A. Raafat, Youssef Madney   +2 more
doaj   +1 more source

Assessing the Consistency of Two Models of Benzene Neurotoxicity Risk Assessment to Create and Validate a Health Risk Screening Guideline Among Fuel Service Workers

International Journal of Occupational Safety and Health
Introduction: This research and development study aimed to (1) evaluate the consistency of two models of benzene neurotoxicity risk assessment (NRA) and (2) create and validate a neurotoxicity risk screening manual among fuel service workers (FSW). Data
Anamai Thetkathuek, Chan Pattama Polyong
doaj   +1 more source

The Incidence of acute Neurotoxicity among some Iraqi colorectal cancer patients treated with oxaliplatin-based chemotherapy

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Oxaliplatin serves as the primary treatment option for colorectal cancer (CRC) at all stages. It induces acute cold-triggered neurotoxicity and chronic cumulative neurotoxicity, leading to potential dose adjustments and influencing patient quality of ...
Rehab AM. Jawad, Bahir Abdul-Razzaq Mshimesh, Qasim S. Al-Mayah, Fawaz Al-Alloosh   +3 more
doaj   +1 more source

Kir6.2-KATP channel: A new target for manganese neurotoxicity induced autophagy impairment and oxidative stress injury

Ecotoxicology and Environmental Safety
Manganese (Mn) is a neurotoxic metal, and epidemiological evidence has demonstrated that chronic occupational exposure to Mn is associated with an elevated risk of neurological disorders.
Changyong Wang, Shanyu Lv, Han Feng, Hongshuo Liang, Kemiao Chen, Guoguo He, Lin Yang, Yaqin Pang, Yonghua He, Chaoyan Ou   +9 more
doaj   +1 more source

Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation

Scientific Reports
Peripheral neurotoxicity is a dose-limiting adverse reaction of primary frontline chemotherapeutic agents, including vincristine. Neuropathy can be so disabling that patients drop out of potentially curative therapy, negatively impacting cancer prognosis.
Irina Utkina-Sosunova, Alessia Chiorazzi, Mariangels de Planell-Saguer, Hai Li, Cristina Meregalli, Eleonora Pozzi, Valentina Alda Carozzi, Annalisa Canta, Laura Monza, Paola Alberti, Giulia Fumagalli, Charles Karan, Yalda Moayedi, Serge Przedborski, Guido Cavaletti, Francesco Lotti   +15 more
doaj   +1 more source