Results 21 to 30 of about 270,958 (352)

Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response

open access: yesiScience, 2023
Summary: Excessive exposure to manganese (Mn) can cause neurological abnormalities, but the mechanism of Mn neurotoxicity remains unclear. Previous studies have shown that abnormal mitochondrial metabolism is a crucial mechanism underlying Mn ...
Shixuan Zhang   +5 more
doaj   +1 more source

Automated detection of immune effector cell‐associated neurotoxicity syndrome via quantitative EEG

open access: yesAnnals of Clinical and Translational Neurology, 2023
Objective To develop an automated, physiologic metric of immune effector cell‐associated neurotoxicity syndrome among patients undergoing chimeric antigen receptor‐T cell therapy.
Christine A. Eckhardt   +19 more
doaj   +1 more source

Antiretroviral neurotoxicity [PDF]

open access: yesJournal of NeuroVirology, 2012
Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV burden, however, poor penetration into the central nervous system (CNS) provides incomplete protection. Although the severity of HIV-associated neurocognitive disorders (HAND) has been reduced, neurological disease is expected to exert an increasing burden as HIV ...
Kevin, Robertson   +2 more
openaire   +2 more sources

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients [PDF]

open access: yes, 2016
Purpose: Methotrexate administration is associated with frequent adverse neurological events during treatment for childhood acute lymphoblastic leukemia.
Baird, Susan F.   +5 more
core   +2 more sources

Auditory fatigue among call dispatchers working with headsets

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2018
Objectives To determine whether call center dispatchers wearing headsets are subject to auditory fatigue at the end of a work shift. Material and Methods Data was gathered at times when call centers were busiest. All call operators wore a headset for up
Thomas Venet   +8 more
doaj   +1 more source

CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and L-type Ca2+ channels upstream of p38 MAPK. [PDF]

open access: yes, 2016
BackgroundThe chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system.
Kaul, Marcus   +5 more
core   +1 more source

Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

open access: yesJournal of Toxicology, 2018
Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric ...
Ayodele Jacob Akinyemi   +1 more
doaj   +1 more source

Amoxicillin-Induced Neurotoxicity: Contribution of a Healthcare Data Warehouse to the Determination of a Toxic Concentration Threshold

open access: yesAntibiotics, 2023
Background: Amoxicillin (AMX)-induced neurotoxicity is well described and may be associated with AMX overexposure. No neurotoxic concentration threshold has been determined thus far.
Sébastien Lalanne   +7 more
doaj   +1 more source

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

open access: yes, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO   +6 more
core   +1 more source

PAC1 Receptor Mediates Electroacupuncture-Induced Neuro and Immune Protection During Cisplatin Chemotherapy

open access: yesFrontiers in Immunology, 2021
Platinum-based chemotherapy is an effective treatment used in multiple tumor treatments, but produces severe side effects including neurotoxicity, anemia, and immunosuppression, which limits its anti-tumor efficacy and increases the risk of infections ...
Shanshan Li   +26 more
doaj   +1 more source

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