Results 11 to 20 of about 177,558 (313)

Inhibition of mitochondrial complex III causes selective dopaminergic neurotoxicity by redox stress in Caenorhabditis elegans [PDF]

open access: yesRedox Biology
Environmental factors including chemical exposures are important contributors to Parkinson's disease (PD). Nearly all well-validated chemicals involved in PD affect mitochondria, and the great majority of those identified inhibit mitochondrial complex I,
Javier Huayta   +3 more
doaj   +2 more sources

Acrylamide neurotoxicity

open access: yesNutritional Neuroscience, 2013
Acrylamide, a food contaminant, belongs to a large class of structurally similar toxic chemicals, 'type-2 alkenes', to which humans are widely exposed. Besides, occupational exposure to acrylamide has received wide attention through the last decades.
BAYDAR, TERKEN, Erkekoglu, Pinar
openaire   +4 more sources

Research Progress on Intervention of Natural Products from Plants in Neurotoxicity of Acrylamide [PDF]

open access: yesShipin Kexue, 2023
Acrylamide (ACR) is a common toxic substance in foods, which can cause serious damage to human organs and systems, especially the nervous system. At present, there are no appropriate measures to prevent and treat ACR neurotoxicity.
ZHANG Mengyu, ZHANG Yanqing, FANG Leilei, XIE Junbo, WEI Yinghao
doaj   +1 more source

Kinin B2 Receptor Mediates Cisplatin-Induced Painful Peripheral Neuropathy by Intracellular Kinase Pathways and TRPA1 Channel Sensitisation

open access: yesPharmaceuticals, 2023
Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1 ...
Gabriela Becker   +3 more
doaj   +1 more source

Neuroinflammation in Bilirubin Neurotoxicity

open access: yesJournal of Integrative Neuroscience, 2023
Bilirubin neurotoxicity is a serious consequence of hyperbilirubinemia, which is the most common disease of the neonatal period. Clinically, bilirubin neurotoxicity can result in motor deficit, auditory dysfunction, cerebral palsy, seizure and ...
Fanhui Zhang, Lihua Chen, Kewen Jiang
doaj   +1 more source

Assessing the association between cefepime percentage free trough level and neurotoxicity

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2022
Background: Cefepime has a known association with neurotoxicity due to its ability to cross the blood–brain barrier. The symptoms of neurotoxicity are highly variable.
Aleena Zia   +3 more
doaj   +1 more source

Lithium neurotoxicity [PDF]

open access: yesPostgraduate Medical Journal, 1979
Summary The peripheral and central neurotoxic effects of lithium carbonate are illustrated by 4 case histories. Lithium neurotoxicity is likely to be more common than the literature suggests. Neurological sequelae may be irreversible and may be associated with therapeutic serum levels. Prevention may be facilitated by more stringent case
P K, Newman, M, Saunders
openaire   +2 more sources

Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia

open access: yesHaematologica, 2021
Symptomatic methotrexate-related central neurotoxicity (MTX neurotoxicity) is a severe toxicity experienced during acute lymphoblastic leukemia (ALL) therapy with potential long-term neurologic complications.
Marion K. Mateos   +18 more
doaj   +1 more source

Neurotoxicity [PDF]

open access: yes, 2022
Neurotoxins are natural or chemical compounds that can disturb the neurological system of mammals. The neurotoxic potential of a neurotoxin is a consequence that may occur if tissue concentrations surpass a particular threshold.

core   +1 more source

Neurotoxicity of Polycyclic Aromatic Hydrocarbons: A Systematic Mapping and Review of Neuropathological Mechanisms

open access: yes, 2022
Several studies present the neurotoxic effects of polycyclic aromatic hydrocarbons (PAHs), a class of environmental pollutants capable of causing neurological deficits. However, a collective review approach to this research topic is scarce.
Olaniran, Ademola O.   +3 more
core   +1 more source

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