Results 31 to 40 of about 171,196 (309)
MicroRNAs in Neurotoxicity [PDF]
Journal of Toxicology, 2012 MicroRNAs are gaining importance as regulators of gene expression with the capability to fine-tune and modulate cellular events. The complex network with their selective targets (mRNAs/genes) pave way for regulation of many physiological processes.
Kaur, P, Armugam, A, Jeyaseelan, K
openaire +4 more sources
JIMD Reports, 2020 Introduction New neurological symptoms in methylmalonic acidemia (MMA) patients after liver and/or kidney transplantation (LKT) are often described as metabolic stroke‐like‐events.
Femke Molema +9 more
doaj +1 more source
Antioxidants, 2022 Soluble oligomeric assemblies of amyloid β-protein (Aβ), called Aβ oligomers (AβOs), have been recognized as primary pathogenetic factors in the molecular pathology of Alzheimer’s disease (AD).
Wataru Araki, Fuyuki Kametani
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Toxins, 2016 There is limited information on the cross-neutralisation of neurotoxic venoms with antivenoms. Cross-neutralisation of the in vitro neurotoxicity of four Asian and four Australian snake venoms, four post-synaptic neurotoxins (α-bungarotoxin, α-elapitoxin-
Anjana Silva +2 more
doaj +1 more source
Role of ferroptosis in hypoxic preconditioning to reduce propofol neurotoxicity
Frontiers in Pharmacology, 2023 Background: An increasing number of studies have reported that neurotoxicity of propofol may cause long-term learning and cognitive dysfunction. Hypoxic preconditioning has been shown to have neuroprotective effects, reducing the neurotoxicity of ...
Jing Chen +8 more
doaj +1 more source
Cefepime neurotoxicity: thresholds and risk factors. A Retrospective Cohort study. [PDF]
, 2020 OBJECTIVES Toxic serum cefepime trough concentrations are not well defined in the current literature. We aimed to define a more precise plasma trough concentration threshold for this antibiotic's neurological toxicity and to identify patients at risk ...
Que, Yok-Ai +11 more
core +2 more sources
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
A case of spinal nerve neurotoxicity with ropivacaine after combined spinal and epidural anesthesia
JA Clinical Reports, 2021 Background Neurotoxicity caused by a local anesthetic after regional anesthesia is a rare but serious problem for anesthesiologists. It is difficult to diagnose neurotoxicity from anesthetics because of the large number of possible diagnoses.
Tsukasa Shimauchi +2 more
doaj +1 more source
Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity [PDF]
, 2003 Although the accumulation of the neurotoxic peptide {beta} amyloid ({beta}A) in the CNS is a hallmark of Alzheimer's disease, the mechanism of {beta}A neurotoxicity remains controversial.
Abramov, A.Y. +2 more
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