Results 41 to 50 of about 213,190 (307)

An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom

Scientific Reports, 2019
We investigated the cardiovascular effects of venoms from seven medically important species of snakes: Australian Eastern Brown snake (Pseudonaja textilis), Sri Lankan Russell’s viper (Daboia russelii), Javanese Russell’s viper (D.
Rahini Kakumanu, Barbara K. Kemp-Harper, Anjana Silva, Sanjaya Kuruppu, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

Cell-specific targeting by engineered M13 bacteriophage expressing VEGFR2 nanobody [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Filamentous bacteriophage M13 was genetically engineered to specifically target mammalian cells for gene delivery purpose. Materials and Methods: A vascular endothelial growth factor receptor 2 (VEGFR2)-specific nanobody was genetically ...
Farideh Ranjibar, Mahdi Habibi-Anbouhi, Fatemeh Kazemi-Lomedasht, Seyed Hamid Aghaee-Bakhtiyari, Ehsan Alirahimi, Mahdi Behdani   +5 more
doaj   +1 more source

Evidence for Resistance to Coagulotoxic Effects of Australian Elapid Snake Venoms by Sympatric Prey (Blue Tongue Skinks) but Not by Predators (Monitor Lizards)

Toxins, 2021
Some Australian elapids possess potently procoagulant coagulotoxic venoms which activate the zymogen prothrombin into the functional enzyme thrombin. Although the activity of Australian elapid prothrombin-activators has been heavily investigated with ...
Nicholas J. Youngman, Joshua Llinas, Bryan G. Fry   +2 more
doaj   +1 more source

The development of the skull of the Egyptian cobra Naja h. haje (Squamata: Serpentes: Elapidae) [PDF]

, 2015
Background: The study of craniofacial development is important in understanding the ontogenetic processes behind morphological diversity. A complete morphological description of the embryonic skull development of the Egyptian cobra, Naja h.
Evans, SE, Khannoon, ER
core   +6 more sources

Recombinant Expression of Bornavirus P24 Protein for Enzyme-Linked Immunosorbent Assay Development [PDF]

The Iranian Journal of Veterinary Science and Technology
Borna disease virus (BDV) is a neurotropic, enveloped and ribonucleic acid (RNA) virus. BDV induces persistent neurologic disease in a wide host range included several vertebrate species as well as human. The BDV genome encodes 6 proteins but p24 protein
Seyedeh Narjes Sadat, Sahar Khalvand, Behzad Ramezani, Mahdi Habibi-Anbouhi, Fatemeh Kazemi-Lomedasht, Hajarsadat Ghaderi, Mahdi Behdani   +6 more
doaj   +1 more source

Evidence in Practice – A Pilot Study Leveraging Companion Animal and Equine Health Data from Primary Care Veterinary Clinics in New Zealand [PDF]

, 2016
Veterinary practitioners have extensive knowledge of animal health from their day-to-day observations of clinical patients. There have been several recent initiatives to capture these data from electronic medical records for use in national surveillance ...
Amezcua, Buckland, Carroll, Chaudhry, Core Team R, Crump, Dórea, Henning, Jones, Kao, Kass, Kearsley-Fleet, Klompas, Lanyon, Li, Lund, Mateus, Mattin, Moore, Muellner, O’Neill, O’Neill, O’Neill, O’Neill, O’Neill, Pfeiffer, Radford, Reeder, Robertson, Robinson, Rogers, Sawford, Spackman, Summers, Sánchez-Vizcaíno, Venom Coding Group, Vourc’h, Wang, Ward, WHO, Wohlfender-Remy, Zurbrigg   +41 more
core   +2 more sources

A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms

Toxins, 2020
Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof, Christina N. Zdenek, James S. Dobson, Nicholas J. Youngman, Francisco Coimbra, Melisa Benard-Valle, Alejandro Alagon, Bryan G. Fry   +7 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Extensive Variation in the Activities of Pseudocerastes and Eristicophis Viper Venoms Suggests Divergent Envenoming Strategies Are Used for Prey Capture

Toxins, 2021
Snakes of the genera Pseudocerastes and Eristicophis (Viperidae: Viperinae) are known as the desert vipers due to their association with the arid environments of the Middle East.
Bianca op den Brouw, Francisco C. P. Coimbra, Lachlan A. Bourke, Tam Minh Huynh, Danielle H. W. Vlecken, Parviz Ghezellou, Jeroen C. Visser, James S. Dobson, Manuel A. Fernandez-Rojo, Maria P. Ikonomopoulou, Nicholas R. Casewell, Syed A. Ali, Behzad Fathinia, Wayne C. Hodgson, Bryan G. Fry   +14 more
doaj   +1 more source

The management of a blood donor bitten by a snake [PDF]

, 2017
The worldwide burden of snakebite is high and venomous snakes are found in many regions of the world and are a threat to public health. In Italy, for instance, viper bites are an infrequent but not negligible event.
Catalano, Liviana, Franchini, Massimo, Liumbruno, Giancarlo M., Marano, Giuseppe, Pupella, Simonetta, Vaglio, Stefania   +5 more
core   +1 more source