Results 1 to 10 of about 18,419 (261)

Antivenom availability, delays and use in Australia

Toxicon: X, 2023
Antivenom is the main treatment for snake envenoming and there are ongoing concerns about availability in resource poor regions of the world. However, effective antivenom treatment for snake envenoming requires more than improved availability of safe and
Geoff K Isbister
exaly   +4 more sources

Indian Polyvalent Antivenom Accelerates Recovery From Venom-Induced Consumption Coagulopathy (VICC) in Sri Lankan Russell’s Viper (Daboia russelii) Envenoming

Frontiers in Medicine, 2022
BackgroundVenom-induced consumption coagulopathy (VICC) is an important clinical consequence of Russell’s viper (Daboia russelii) envenoming. There is limited evidence for antivenom effectiveness in resolving VICC.
Anjana Silva, Anjana Silva, Anjana Silva, Fiona E. Scorgie, Lisa F. Lincz, Kalana Maduwage, Sisira Siribaddana, Geoffrey K. Isbister, Geoffrey K. Isbister   +8 more
doaj   +2 more sources

Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives

Toxins, 2022
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia, Avni Blotra, Karthikeyan Vasudevan   +2 more
doaj   +2 more sources

Early Adverse Reactions to Snake Antivenom: Poison Center Data Analysis

Toxins, 2022
Antivenom is an essential treatment for snake envenomation; however, early adverse reactions (EARs) are major limitations to its use. We performed a retrospective cross-sectional study using Ramathibodi Poison Center data (January 2016 to December 2017 ...
Charuwan Sriapha, Panee Rittilert, Taksa Vasaruchapong, Sahaphume Srisuma, Winai Wananukul, Satariya Trakulsrichai   +5 more
doaj   +2 more sources

Pharmacological Treatments and Adverse Reactions Following Snake Antivenom Therapy: A Collaborative Study by Healthcare Professionals in the Southernmost Region of Thailand [PDF]

Toxins
The administration of specific immunoglobulin G-based antivenoms is a key strategy for treating snakebite envenoming victims. However, serious adverse reactions, such as anaphylaxis or serum sickness, are frequently observed following such administration.
Panuwat Promsorn, Wittawat Chantkran, Musleeha Chesor, Janeyuth Chaisakul   +3 more
doaj   +2 more sources

Adverse Reactions after Administration of Antivenom in Korea

Toxins, 2020
Kovax® antivenom is the main treatment for toxins produced by the Gloydius species. However, research on adverse reactions after Kovax® antivenom administration is scarce.
Jin Seok Shim, Hyunggoo Kang, Yongil Cho, Hyungoo Shin, Heekyung Lee   +4 more
doaj   +2 more sources

Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites. [PDF]

Nature
Each year, snakebite envenoming claims thousands of lives and causes severe injury to victims across sub-Saharan Africa, many of whom depend on antivenoms derived from animal plasma as their sole treatment option1.
Ahmadi S, Burlet NJ, Benard-Valle M, Guadarrama-Martínez A, Kerwin S, Cardoso IA, Marriott AE, Edge RJ, Crittenden E, Neri-Castro E, Fernandez-Quintero ML, Nguyen GTT, O'Brien C, Wouters Y, Kalogeropoulos K, Thumtecho S, Ebersole TW, Dahl CH, Glegg-Sørensen EU, Jansen T, Boddum K, Manousaki E, Rivera-de-Torre E, Ward AB, Morth JP, Alagón A, Mackessy SP, Ainsworth S, Menzies SK, Casewell NR, Jenkins TP, Ljungars A, Laustsen AH.   +32 more
europepmc   +2 more sources

Availability, accessibility and use of antivenom for snakebite envenomation in Africa with proposed strategies to overcome the limitations

Toxicon: X, 2023
Africa remains one of the regions with the highest incident and burden of snakebite. The goal of the World Health Organization to halve the global burden of snakebite by 2030 can only be achieved if sub-optimal access to antivenoms in the most affected ...
M. Dalhat, J. Potet, A. Mohammed, Nafiisah Chotun, H. Tesfahunei, A. Habib   +5 more
semanticscholar   +1 more source

Cross-Reactivity and Neutralization Capacity of Polyspecific Antivenom Produced by Razi Institute against Three Species of Buthidea Family Scorpions [PDF]

Asia Pacific Journal of Medical Toxicology, 2019
Background: Scorpion sting is a significant health problem in southern provinces of Iran. Many thousands of people are stung by different species of scorpions annually. More than 60 scorpion species have been reported to be present in Iran. However, Razi
Bahzad Masihipour, Abbas Zare Mirakabadi, mehdi kheirollahpour, Hadi Rabiei, Ali Hedayat   +4 more
doaj   +1 more source

Venoms, venomics, antivenomics [PDF]

FEBS Letters, 2009
Venoms comprise mixtures of peptides and proteins tailored by Natural Selection to act on vital systems of the prey or victim. Here we review our proteomic protocols for uncoiling the composition, immunological profile, and evolution of snake venoms. Our long‐term goal is to gain a deep insight of all viperid venom proteomes.
Calvete Chornet, Juan José, Sanz, Libia, Angulo Ugalde, Yamileth, Lomonte, Bruno, Gutiérrez, José María   +4 more
openaire   +4 more sources